Various approaches for enhancing treatment of target tissue using a source of focused ultrasound while limiting damage to non-target tissue include selecting a frequency of ultrasound waves transmitted from the source of focused ultrasound for generating a focus in the target tissue; providing microbubbles having the first size distribution such that at least 50% of the microbubbles have a radius smaller than a critical radius corresponding to a resonance frequency matching the selected frequency of ultrasound waves; and applying the ultrasound waves at the selected frequency to treat the target tissue.

Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.

Removable marker implants having fiducial markers disposed on multiple elongate members extend and splay laterally outward when deployed thereby providing improved 3D localization and tracking of a portion of the patient's body for stereotactic radiosurgery. Such an approach is particularly useful for tracking of the uterus during radiosurgery treatment of uterine fibroids. Such implants can include an outer sheath that contains the multiple elongate members during delivery into the portion of the body. The elongate members can be slidably disposed within the shaft and advanced into an expanded deployed position by advancement of an applicator shaft or rod within the sheath. Marker implant can also be integrally formed implants with flexible arms having fiducial markers thereon that can be constrained in a sheath for delivery and resiliently splay laterally outward when released from the shaft. Methods of delivery and deployment are also provided.

Medical systems and methods are provided in the present disclosure. The medical system may include a first medical device mounted on a first gantry. The first medical device may be configured to perform a first operation on a first region of an object. The medical system may also include a second medical device mounted on a second gantry. The second medical device may be configured to perform a second operation on a second region of the object. The second gantry may rotate relative to the first gantry. The first region may at least partially overlap the second region.

An energy radiation treatment method comprises: administering a medicinal agent to an affected part; performing energy radiation with a predetermined energy on the affected part; and confirming therapeutic effects by the energy radiation on the affected part, wherein in the administering, a determination based on at least one ultrasound image based on ultrasound waves reflected from the affected part is performed.

A radiation treatment device is provided. The device includes an imaging unit and a single radiotherapy unit adjacent to a second end of the imaging unit. The imaging unit includes a first opening at a first end of the imaging unit adapted to receive a patient; at least one imaging source; and at least one imager arranged opposite the imaging source. The imaging source and the imager are rotatable about the rotational axis. The radiotherapy unit includes a source body carrying radioactive sources and a collimator having collimation channels. The collimation channels permit treatment beams emitted by the radioactive sources to be projected inside the imaging unit and focused at an intersection point located within an imaging beam of the imaging unit. The source body and the collimator are arranged concentric about the rotational axis and close a second opening at the second end.

A radiotherapy device and a control driving method thereof are provided. The radiotherapy device includes a radiation source apparatus having a plurality of radiation sources, a source carrier and a collimator. The source carrier includes a source box and a source box region conforming to a shape of the source box, the source box is detachably fixed at the source box region, the plurality of radiation sources are mounted in the source box, the source box is provided with a first connecting part, the source carrier is provided with a second connecting part, and the first connecting part is configured to connect the second connecting part.

Systems and methods are provided for registering images. The systems and methods perform operations comprising: receiving, at a first time point in a given radiation session, a first imaging slice corresponding to a first plane; encoding the first imaging slice to a lower dimensional representation; applying a trained machine learning model to the encoded first imaging slice to estimate an encoded version of a second imaging slice corresponding to a second plane at the first time point to provide a pair of imaging slices for the first time point; simultaneously spatially registering the pair of imaging slices to a volumetric image, received prior to the given radiation session, comprising a time-varying object to calculate displacement of the object; and generating an updated therapy protocol to control delivery of a therapy beam based on the calculated displacement of the object.

Systems and techniques may be used to estimate a patient state during a radiotherapy treatment. For example, a method may include generating a dictionary of expanded potential patient measurements and corresponding potential patient states using a preliminary motion model. The method may include training, using a machine learning technique, a correspondence motion model relating an input patient measurement to an output patient state using the dictionary. The method may include estimating, using a processor, the patient state corresponding to an input image using the correspondence motion model.

A method and system are disclosed for radiosurgical treatment of moving tissues of the heart, including acquiring at least one volume of the tissue and acquiring at least one ultrasound data set, image or volume of the tissue using an ultrasound transducer disposed at a position. A similarity measure is computed between the ultrasound image or volume and the acquired volume or a simulated ultrasound data set, image or volume. A robot is configured in response to the similarity measure and the position of the transducer, and a radiation beam is fired from the configured robot.