Disclosed herein are systems and methods for rapidly delivering high doses of radiation, also known as, flash dose radiotherapy or flash radiotherapy. One variation of a system for flash radiotherapy has a plurality of therapeutic radiation sources on a support structure (e.g., a gantry or arm) and configured to toward a patient target region, and a controller in communication with all of the therapeutic radiation sources. The controller is configured to activate the plurality of therapeutic radiation sources simultaneously so that the patient target region rapidly receives a high dose of radiation, e.g. the entire prescribed dose of radiation. In some variations, a flash radiotherapy system has a pulsed, high-power source that may be used to generate an X-ray pulse that delivers a dose having a dose rate from about 7.5 Gy/s to about 70 Gy/s. Flash radiotherapy systems may also include one or more imaging systems mounted on the support structure.

An MRI-CT system and methods for sequentially (or simultaneously) imaging a subject involving a CT component for initially performing CT imaging, an MR component for subsequently performing MR imaging, the MR component and the CT component disposable in relation to one another in at least one of linearly aligned and colinearly aligned, and a movable barrier disposable between the CT component and the MR component, the movable barrier comprising a magnetic shield, and the movable barrier disposable in one of an open position and a closed position during MRI scanning by the MR component and in a closed position during CT scanning by the CT component.

This imaging controller of the imaging controller includes: an imager position determination section that determines whether or not a first imager is located in an overlapping region where a rotation range of the first imager and a rotation range of a second imager overlap each other when a rotation mechanism rotates the first and second imagers by an angle greater than the predetermined angle; and an imaging timing control section that causes one or both of the first and second imagers to perform imaging when arrival of an imaging timing is detected and that causes only the second imager to perform imaging in at least one imaging timing whose arrival is detected in a state where the imager position determination section determines that the first imager is located in the overlapping region.

A radiotherapy system acquires an image which is necessary for positioning of a patient for radiation treatment and enables grasping of a positional relationship of a target in a treatment radiation irradiated state, a radiation passing area and a critical organ. An X-ray imaging device is attached to the rotatable support device and configured to apply X-rays to the subject from plural directions while rotating around the subject to perform X-ray imaging. A target recognizing device recognizes a three-dimensional position of the target in the subject from X-ray images acquired by the X-ray imaging device; and CT image generating devices are configured to select, from the X-ray images acquired by the X-ray imaging device, the images in which the position of the target recognized by the recognizing device satisfies the treatment radiation irradiation condition for the motion tracking treatment to perform image reconstruction and generate a cone beam CT image.

The invention provides an imaging method, a system and a radiotherapy device based on dual-energy CBCT. The method includes: rotating the large gantry by 90°, and obtaining the megavolt projection data from 0° to 90° and the kilovolt projection data from 90° to 180° in the process of rotation; using a predetermined reconstruction algorithm to reconstruct the megavolt projection data and the kilovolt projection data respectively to obtain the megavolt CBCT volume image and the kilovolt CBCT volume image; using the preset algorithm to obtain the corrected kilovolt projection data; using the preset algorithm to obtain corrected megavolt projection data; the corrected kilovolt projection data and the corrected megavolt projection data are used for hybrid reconstruction to obtain CBCT volume image. By using the kilovolt projection image and the megavolt projection image for hybrid reconstruction, CBCT volume image containing both soft tissue information and bone information are obtained.

A method and apparatus to automatically control the timing of an image acquisition by an imaging system in developing a correlation model of movement of a target within a patient.

Methods, devices, and systems can be used to improve accuracy and precision of stereotactic radiosurgery. For example, this document provides methods and materials for using a fiducial marker device for stereotactic radiosurgery of ocular disorders. The fiducial marker device of the invention enables positional tracking of the target tissue during the stereotactic radiosurgery procedure despite occasional movement of the eye being subjected to stereotactic radiosurgery.

An image-guided therapy delivery system includes a therapy generator configured to generate a therapy beam directed to a time-varying therapy locus within a therapy recipient, an imaging input configured to receive imaging information about a time-varying target locus within the therapy recipient, and a therapy controller. The therapy generator includes a therapy output configured to direct the therapy beam according to a therapy protocol. The therapy controller is configured to automatically generate a predicted target locus using information indicative of an earlier target locus extracted from the imaging information, a cyclic motion model, and a specified latency, and automatically generate an updated therapy protocol to align the time-varying therapy locus with the predicted target locus.

Subject positioning systems and methods are provided. A method may include obtaining first information of at least part of a subject when the subject is located at a preset position, and determining, based on the first information, a first position of each of one or more feature points located on the at least part of the subject. The method may include obtaining, using an imaging device, second information of the at least part of the subject when the subject is located at a candidate position. The method may further include determining, based on the second information, a second position of each of the one or more feature points, a first distance between the first position and the second position for each feature point of the one or more feature points, and a target position of the subject based at least in part on the one or more first distances.

An example particle therapy system includes a gantry having a beamline structure configured to direct a particle beam that is monoenergetic from an output of a particle accelerator towards an irradiation target, where the beamline structure includes magnetic bending elements to bend the particle beam along a length of the beamline structure; and an energy degrader downstream of the beamline structure relative to the particle accelerator, where the energy degrader is configured and controllable to change an energy of the particle beam prior to at least part of the particle beam reaching the irradiation target.