Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enough information to determine the location of a target region due to, for example, poor or low contrast and/or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images.

Systems, methods, and computer software are disclosed for acquiring images during delivery of a radiation beam, the images capturing at least a portion of a shape representative of a radiation field generated by a radiation delivery system that includes a radiation source configured to deliver the radiation beam.

A radiotherapy device and a control driving method thereof are provided. The radiotherapy device includes a radiation source apparatus having a plurality of radiation sources, a source carrier and a collimator. The source carrier includes a source box and a source box region conforming to a shape of the source box, the source box is detachably fixed at the source box region, the plurality of radiation sources are mounted in the source box, the source box is provided with a first connecting part, the source carrier is provided with a second connecting part, and the first connecting part is configured to connect the second connecting part.

According to one embodiment, a radiotherapy planning apparatus includes processing circuitry. The processing circuitry is configured to acquire dose rate distribution information indicating distribution of a dose rate in an irradiation path of radiation based on irradiation conditions of the radiation. The processing circuitry is configured to acquire irradiation effect discrimination information for discriminating irradiation effects of radiation in the irradiation path based on the acquired dose rate distribution information.

A method for driving a leaf of a multi-leaf collimator (MLC) mounted on a collimator that is mounted on a gantry is provided. The method may include obtaining an electrical current of an actuator of the leaf; generating a target control signal based on the electrical current of the actuator; and causing a drive circuit to generate a driving signal for driving the leaf to move by providing the target control signal to the drive circuit.

Disclosed are a neutron capture therapy device and an operation method of a monitoring system. The neutron capture therapy device includes a neutron beam irradiation system, a detection system and the monitoring system. The neutron beam irradiation system generates a neutron beam for performing neutron irradiation therapy on a sick body. The detection system is used for detecting irradiation parameters during a neutron beam irradiation therapy, and the monitoring system is used for controlling the whole neutron beam irradiation process. The monitoring system includes a storage part for storing the irradiation parameters, a control part for executing a therapy plan according to the irradiation parameters stored in the storage part, and a correction part for correcting part of the irradiation parameters stored in the storage part. The disclosure improves the accuracy of the dosage of the neutron beam for irradiating the sick body.

A method of optimizing delivery of a particle beam at a target is disclosed. The particle beam is delivered from an output device at a plurality of control points. In implementations, the method comprises delivering a substantially continuous particle beam about the plurality of control points, iteratively adjusting a delivery time of the substantially continuous particle beam about the plurality of control points, and processing to undertake at least one of (i) pre-defining energy layers based on one or both of the control points and a control point sampling frequency, or (ii) sorting the energy layers.

Disclosed herein are radiotherapy systems and methods that can display a workflow-oriented graphical user interface(s). In an embodiment, a system comprises a first display in communication with a server, the first display configured to display a first graphical user interface; a second display in communication with the server, the second display configured to display a second graphical user interface, wherein the server is configured to: present the first graphical user interface for displaying on the first display, wherein the first graphical user interface contains one or more pages corresponding to one or more stages of a radiotherapy treatment, wherein the server transitions from a first page of the one or more pages representing a first stage to a second page of the one or more pages representing a second stage responsive to an indication that at least a predetermined portion of tasks associated with the first stage has been satisfied.

A phantom, calibration system and calibration method are described. The phantom having a phantom body and an X-ray luminescent material, wherein at least a portion of the X-ray luminescent material is on a surface of the phantom.

A balloon applicator for an intraoperative radiation therapy system includes an x-ray beam shaping component for emitting x-rays in a plurality of possible directions in three dimensions. The balloon applicator includes connecting structure for connecting to the intraoperative radiation therapy system and an inflatable balloon contactor having an outer surface. The balloon applicator has a beam hardening system including a beam hardening compound disposed between the x-ray beam shaping component and the outer surface of the balloon. The beam hardening system is capable of hardening the beam in beam directions in three dimensions. An intraoperative radiation therapy system and a method for conducting intraoperative radiation therapy are also disclosed.