Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.

A plurality of shift images are generated by shifting a fluoroscopic image by a prescribed increment within a prescribed range in a craniocaudal direction. Then, a normalized correlation coefficient between a DRR image and each of the plurality of shift images is calculated. Next, a shift amount of the shift image corresponding to the largest normalized correlation coefficient among the plurality of normalized correlation coefficients is determined to be the positional deviation.

A system and method of performing prospective and retrospective on-line adaptive radiotherapy. The method includes performing, during a treatment delivery session, delivery of a dose of radiation to an anatomical volume. The method includes detecting, during the treatment delivery session, a current state of the anatomical volume. The method includes predicting a future change in the current state of the anatomical volume during the treatment delivery session. The method includes adjusting, while the anatomical volume is in the current state, the treatment delivery to anticipate the future change in the anatomical volume.

A system and method of performing prospective and retrospective on-line adaptive radiotherapy. The method includes performing, during a treatment delivery session, delivery of a dose of radiation to an anatomical volume. The method includes detecting, during the treatment delivery session, a current state of the anatomical volume. The method includes predicting a future change in the current state of the anatomical volume during the treatment delivery session. The method includes adjusting, while the anatomical volume is in the current state, the treatment delivery to anticipate the future change in the anatomical volume.

A computer-implemented method of performing a treatment fraction of radiation therapy comprises: determining a current position of a target volume of patient anatomy; based on the current position of the target volume, computing an accumulated dose for non-target tissue proximate the target volume; determining that the accumulated dose is less than a current value for a dose budget of the non-target tissue; and in response to the accumulated dose being less than the current value for the dose budget, applying a treatment beam to the target volume while the target volume is in the current position.

A radiotherapy device, a method and a computer readable medium are disclosed. The radiotherapy device includes a radiation source and a controller. The radiation source is configured to apply radiation to a subject. The controller is configured to determine an overlap between a defined volume of the subject and an isodose surface and to instruct the radiation source to halt application of the radiation based on the determination.

Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.

Disclosed herein is a medical system (100, 300, 500) comprising a processor (104) configured for controlling the medical system and a memory (110) for storing machine executable instructions. Execution of the instructions causes the processor to receive (200) four-dimensional Dixon magnetic resonance image data (122). The four-dimensional Dixon magnetic resonance imaging data is T1 weighted. The four-dimensional Dixon magnetic resonance image data is synchronized to a respiratory signal (124). Execution of the instructions further causes the processor to reconstruct (202) synthetic four-dimensional computed tomographic image data (12) from the four-dimensional Dixon magnetic resonance imaging data. The four-dimensional Dixon magnetic resonance imaging data is synchronized to the respiratory signal.

A method of customized breathing maneuver guidance during radiotherapy treatment by configuring to a treatment couch an augmented reality system that includes a mounting assembly, a position measurement module to measure a distance from a fixed position to a patient anatomic region during a breathing cycle, and a breath monitoring and instruction screen viewable by the patient disposed proximal to the fixed position, where the patient monitors and controls a state of their breathing cycle in real time from breath state information displayed on the instruction screen, and determining the anatomic region for monitoring to measure the distance from the fixed position, determining a patient-customized breath hold amplitude by measuring a distance between a baseline exhale position a maximum inhale position, and entering breath hold amplitude data to a computer for subsequent breath hold guidance regardless of the treatment couch model setup and patient weight variations.

Disclosed are systems and methods for the treatment of cardiac arrhythmias.