A radiation system is provided. The radiation system may include a bore accommodating an object, a rotary ring, a first radiation source and a second radiation source mounted on the rotary ring and a processor. The first radiation source may be configured to emit a first cone beam toward a first region of the object. The second radiation source may be configured to emit a second beam toward a second region of the object, the second region including at least a part of the first region. The processor may be configured to obtain a treatment plan of the object, the treatment plan including parameters associated with radiation segments. The processor may be further configured to control an emission of the first cone beam and/or the second beam based on the parameters associated with the radiation segments to perform a treatment and a 3-D imaging simultaneously.

A Cherenkov-based or thin-sheet scintillator-based imaging system uses a radio-optical triggering unit (RTU) that detects scattered radiation in a fast-response scintillator to detect pulses of radiation to permit capture of Cherenkov-light or scintillator-light images during pulses of radiation and background images at times when pulses of radiation are not present without need for electrical interface to the accelerator that provides the pulses of radiation. The Cherenkov images are corrected by background subtraction and used for purposes including optimization of treatment, commissioning, routine quality auditing, R&D, and manufacture. The radio-optical triggering unit employs high-speed, highly sensitive radio-optical sensing to generate a digital timing signal which is synchronous with the treatment beam for use in triggering Cherenkov light or scintillator light imaging.

Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enough information to determine the location of a target region due to, for example, poor or low contrast and/or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images.

Systems for establishing a reproducible breath-holding pattern during radiotherapy are disclosed. An exemplary image-guided radiotherapy system (100) may include an airway breathing controller (ABC) device (160), which may block airflow to the patient during imaging and/or radiotherapy to immobilize a target tumor. A patient may practice breath-holding during a training session until a reproducible breath-hold pattern is established. The patient may perform the breath-hold pattern in imaging and/or radiotherapy sessions, during which physiological signals may be measured from the patient and compared to baseline signals collected during the training session. Variation between measured signals and baseline signals may indicate unreproducible breath-holding, in which case radiation delivery may be altered or halted.

A detection apparatus and a method are provided for detecting a respiratory movement of a patient. The detection apparatus includes at least two metallic U-shaped signal coupling elements that are interleaved so that between the signal coupling elements arises at least one coupling point at which a signal may be transferred between the two signal coupling elements. Analysis electronics are configured to detect a change in a received signal produced in a second of the signal coupling elements that is acting as a receiver in the near-field region of the first signal coupling elements as a result of a signal given for one of the signal coupling elements that is acting as a transmitter being coupled into the second of the signal coupling elements, which change indicates the respiratory movement.

A radiation treatment planning apparatus according to one aspect includes a processing circuitry. The processing circuitry obtains time-series medical images. The processing circuitry specifies a first time phase in which radiation irradiation is performed and a second time phase in which no radiation irradiation is performed, in a period corresponding to the time-series medical images based on a positional relationship between a treatment target region and at-risk region of a patient included in the time-series medical images. The processing circuitry generates a treatment plan based on a medical image of the specified first time phase.

A system to align an object using a light reflector, including: an input unit for pre-setting a first region in which radiation is to be emitted to the object; a display unit for displaying information on the first region; a radiation unit for emitting radiation to the first region; a reflector formed to correspond to the shape of the first region and configured to be attached to the first region; a light unit for emitting light in the same direction as the radiation to the first region; a camera for photographing a region of the reflector when the reflector reflects light emitted by the light unit; and a control unit for controlling the display unit to display the region of the light reflector which reflects light photographed by the camera, and determining whether the radiation is aligned to the first region of the object based on whether the region of the light reflector is included in the shape of the first region.

A control unit 30 includes: an image storage unit 31 constituted by a first image storage unit 32 that stores multiple templates created on the basis of an image including a specific site of a subject and a second image storage unit 33 that stores multiple positive images created on the basis of an image including the specific site of the subject; a learning unit 34 that, on the basis of the multiple positive images, creates a discriminator by machine learning; a position selection unit 35 that, with use of multiple images obtained by collecting an image including the specific site of the subject at a predetermined frame rate, selects a region including the specific site by machine learning using the discriminator; and a position detection unit 36 that detects the position of the specific site by performing template matching using the multiple templates on the region including the specific site selected by the position selection unit 35.

The inventive approach positionally determines a periodically moving structure of a patient's anatomy by acquiring one or more images of a periodically moving anatomical structure of interest. The exposure time of each image covers at least one whole motion cycle of the structure, such that each acquired image depicts at least one whole motion cycle.

A method of determining a biophysical model for a lung of a patient from multiple x-ray measurements corresponding to different breathing phases of the lung is provided. The method includes extracting multiple displacement fields of lung tissue from the multiple x-ray measurements corresponding to different breathing phases of the lung. Each displacement field represents movement of the lung tissue from a first breathing phase to a second breathing phase and each breathing phase has a corresponding set of biometric parameters. The method includes calculating one or more biophysical parameters of a biophysical model of the lung using the multiple displacement fields of the lung tissue between different breathing phases of the lung and the corresponding sets of biometric parameters.