Systems and methods are provided for single isocenter radiotherapy of multiple targets. Conformal arc information may be used in a Conformal Arc Informed Volumetric Modulated Arc Therapy (CAVMAT) method that includes single isocenter radiotherapy of multiple targets where conformal multi-leaf collimator (MLC) trajectories may be used as the starting point for limited inverse optimization. Single isocenter radiotherapy of multiple targets may provide flexibility with less complex MLC trajectories, and fully block between targets with the MLC.

The invention provides a patient shuttle system and an irradiation system for particle therapy. A patient shuttle system of one embodiment of the invention includes: a patient table (110) adapted to carry a patient; a patient table drive unit (120) that moves and/or rotates the patient table; and a transfer unit (130) having a base (131) on which the patient table drive unit is placed. In a home position state of the patient shuttle system (100), the patient table and first and second arms of the patient table drive unit are configured to be folded in the height direction (Z-axis). A robot arm base connected to the second arm is fixed at a position off the center of the base in plan view, and thereby a helper space (135) where a helper may ride is secured on the base. The robot arm base is fixed in a recess (138) provided in the base.

A method may include acquiring a first image including a target point and a first reference point, the target point corresponding to at least one part of a subject, the first reference point corresponding to a first marker disposed on the couch of the medical device; determining a first spatial position of the first marker, the first spatial position corresponding to a first working position of the couch; determining a first spatial position of the at least one part of the subject based on the first image and the first spatial position of the first marker; determining a second spatial position of the first marker, the second spatial position corresponding to a second working position of the couch; determining a second spatial position of the at least one part of the subject based on the second spatial position of the first marker and the first spatial position of the at least one part of the subject. In some embodiments, the method may further include adjusting the second working position of the couch based on the second spatial position of the at least one part of the subject.

The invention relates to a system (1) for image based guidance of treatment delivery to a patient. The system is adapted to determine spatial parameters defining a position and orientation of an ultrasound probe (8) on the basis of a reference image which has been used for preparing a treatment plan. This can provide a certain degree of automation in arranging the ultrasound probe, in order to decrease user dependence and improve the usability for relatively untrained operators. Moreover, since the reference image is also used for generating the treatment plan, i.e. since the same image is used for generating the treatment plan and for determining the position and orientation of the ultrasound probe, it is not necessarily required to acquire an additional image. This can allow for a reduced radiation dose applied to the parts of the patient not being the target to be treated.

A computer-implemented medical method of irradiation treatment planning is provided. Therein, an initial coverage volume for a planning target volume, which is to be irradiated in an irradiation treatment with a prescribed dose, is provided. Further, at least one constraint indicative of an allowed dose for an organ at risk is provided. Applying an initial irradiation treatment plan, an organ dose deposited in at least a partial volume of the organ at risk is calculated. Based on comparing the organ dose to the at least one constraint, an amount of violation is determined. Taking into account the determined amount of violation, a reduction coverage volume is calculated for the planning target volume and a virtual planning object is generated based on changing a volume of the organ at risk, such that an overlap region of the virtual planning object and the planning target volume corresponds to the reduction coverage volume. By removing at least a part of the overlap region from the planning target volume, an optimized planning target volume is generated.

According to one embodiment, the radiotherapy system includes a medical image collecting device, a body surface data collecting device and processing circuitry. The medical image collecting device collects medical three-dimensional image data of the patient at the time of treatment planning. The body surface data collecting device collects body surface data representing a three-dimensional body surface of the patient at the time of treatment planning. The processing circuitry may generate integrated data in which at least one of the medical three-dimensional image data and the treatment target region data included in the medical three-dimensional image data, and the body surface data are integrated into an identical three-dimensional coordinate system.

A virtual beam's-eye view of a planning target volume is generated based on volumetric image data acquired immediately prior to radiation therapy by a radiation therapy system. The virtual beam's-eye view can then be displayed to confirm that, with the patient disposed in the current position, the planned beam-delivered treatment extends beyond the surface of the skin. In some embodiments, the virtual beam's-eye view can be displayed in conjunction with a beam's-eye view that is generated based on volumetric image data acquired during treatment planning, to create a blended beam's-eye view. In some embodiments, a field outline of a treatment beam can be superimposed on the blended beam's-eye view, thereby illustrating whether the planned beam-delivered treatment extends beyond the surface of the skin of the patient. The blended beam's-eye view can facilitate a manual confirmation process that verifies the planned beam-delivered treatment extends beyond the surface of the skin.

A method and system for using in a two-modality apparatus. The two-modality apparatus comprises a couch with a table top, a first modality unit and a second modality unit. A second image of a target portion of an object when the table top is at a second working position of the second modality unit may be acquired. A second sag of the table top at a second measurement point of the table top according to the second image may be determined based on the image. A difference between a first sag of the table top at a first measurement point of the table top and the second sag may be estimated based on the second sag and standard data. The standard data provides a relationship relating to a sag of the table top positioned between the first modality unit and second modality unit.

A method includes detecting a potential setup error in a radiation treatment delivery session of a radiation treatment delivery system, wherein the setup error corresponds to a change in a current position of a treatment target relative to a prior position of the treatment target, and wherein the change includes a rotation relative to the prior position of the treatment target. The method further includes modifying, by a processing device, one or more planned leaf positions of a multileaf collimator (MLC) of a linear accelerator (LINAC) of the radiation treatment delivery system to compensate for the potential setup error corresponding to the rotation of the prior position of the treatment target.

A therapeutic apparatus comprising a radiotherapy apparatus for treating a target zone and a magnetic resonance imaging system for acquiring magnetic resonance imaging data. The radiotherapy apparatus comprises a radiotherapy source for directing electromagnetic radiation into the target zone. The radiotherapy apparatus is adapted for rotating the radiotherapy source at least partially around the magnetic resonance magnet. The magnetic resonance imaging system further comprises a radio-frequency transceiver adapted for simultaneously acquiring the magnetic resonance data from at least two transmit-and-receive channels. The therapeutic apparatus further comprises a processor and a memory containing machine executable instructions for the processor. Execution of the instructions causes the processor to: calibrate the transmit-and-receive channels; acquire the magnetic resonance data; reconstruct a magnetic resonance image; register a location of the target zone in the image; and generate radiotherapy control signals using the registered image.