A01N1/0257

Vitrification freezing treatment device for cells and treatment method thereof

The invention discloses a vitrification freezing treatment device for cells. The vitrification freezing treatment device for cells includes a straw device, a pre-freezing device, a freezing unit, a driving device, a control unit and a carrying table used for carrying cell carriers, wherein the straw device is connected with the driving device in a driven mode, the driving device is in signal connection with the control unit, the straw device comprises straws used for obtaining cells in the cell carriers, the control unit is used for controlling the driving device to drive the straw device to obtain cells and to transfer the cells to the freezing unit, and the pre-freezing device is used for pre-freezing the straws when the straw device transfers the obtained cells to the freezing unit.

APPARATUS TO FACILITATE TRANSFER OF BIOLOGICAL SPECIMENS STORED AT CRYOGENIC CONDITIONS

A system and method facilitates transfers of specimen containers (e.g., vials with caps) between storage cassettes and carrier cassettes. The storage cassettes are designed to be stored in cryogenic refrigerators while the carrier cassettes are designed to be temporarily stored in a portable carrier. Identification information is read from wireless transponders carried by the specimen containers. Visual mappings of the positions of the specimen container in the cassettes is provided. Presence and position of the specimen containers in the cassettes is verified, and alerts of inconsistencies provided along with corrective commands. Inventories of specimen container and even specific specimen holders are provided.

CRYOGENIC STORAGE TRANSPORTATION TRACKING SYSTEM
20230410991 · 2023-12-21 ·

A system for wireless identification of pharmaceutical products stored in a storage device is disclosed. The system includes a plurality of racks adapted to hold a plurality of pharmaceutical products, wherein each rack comprises one or more apertures; a plurality of remotely readable tags each adapted to be affixed to one or more of the pharmaceutical products, and at least one antenna operatively connected to a reader configured to interrogate the remotely readable tags. The reader is operatively connected to a computerized inventory system that is configured to receive information about each remotely readable tag, and the reader detects a position of each remotely readable tag and associated pharmaceutical product on the plurality of racks.

Cryogenic container
10935298 · 2021-03-02 · ·

The invention relates to a cryogenic container for storing and/or transporting a medium, in particular a biochemical and/or medical product. The cryogenic container comprises at least one primary container, which has at least one flexible film bag. The flexible film bag is designed to receive the medium. The cryogenic container furthermore comprises at least one secondary container, which at least partially surrounds the primary container and is preferably at least partially flexible. The secondary container has at least one opening for insertion of the primary container. The secondary container furthermore has at least one preferably at least partially flexible outer sleeve. The secondary container furthermore has at least one heat exchanger space, which is arranged between the outer sleeve and the flexible film bag and receives at least one fluid heat exchange medium.

Extremely fast freezing, low-temperature blast freezer

A freezer includes a plurality of shelves in an insulated payload bay; a plurality of evaporators coupled to the payload bay with a multiplicity of coolant tubes in each evaporator, wherein each tube enters and then exits the payload bay, further comprising one or more cryogenic valves coupled to the coolant tubes; a pump to force coolant flowing through the evaporators with a pressure of at least 90 psi to supply the coolant at each evaporator with at least 80 gallons per hour of coolant; and a plurality of fans to circulate cooled air in the payload bay.

DEVICE AND METHOD FOR FREEZE DRYING BIOLOGICAL SAMPLES
20210037814 · 2021-02-11 ·

A method for freeze-drying a biological sample of mammalian cells or tissue including placing a biological sample on or in a structure to increase a temperature of the biological sample and with the biological sample in a closed chamber applying a vacuum to the chamber to lower a pressure within the chamber, cooling the chamber to lower a temperature within the chamber and applying heat to the biological sample within the chamber. The biological sample can include one or more of stem cells, hematopoietic stem cells, mesenchymal stem cells, embryonic stem cells, induced pluripotent stem cells, sperm, oocytes, embryos, ovarian tissue, uterine tissue or testicular tissue.

Storage Tank Device Configured to Prevent Ice Formation
20210086978 · 2021-03-25 · ·

A cryogenic storage device includes a storage tank having an inner tank, an intermediate tank and an outer tank spaced apart from each other so as to define a fluid reservoir for holding a cryogenic liquid and a thermal insulative space bounding the fluid reservoir. A top cover closes the open top. An inlet supplies the cryogenic liquid to the fluid reservoir. A fluid sensor is configured to detect a pressure within the cryogenic storage device and is removably disposed within the fluid reservoir so as to allow an ice formation to be thawed without having to thaw the entire cryogenic storage device.

THERMAL MONITORING SYSTEM FOR TEMPERATURE-SENSITIVE STORAGE CONTAINERS
20210072109 · 2021-03-11 ·

Example aspects of a thermal monitoring system are disclosed. The thermal monitoring system can comprise a cryogenic storage container comprising an external wall and an internal wall, wherein a cold cryogenic liquid is housed within the internal wall, and wherein a vacuum is formed between the external wall and the internal wall; a thermal imaging camera configured to measure temperatures within a region of interest, wherein the cryogenic storage container is oriented within the region of interest and the thermal imaging camera measures an external temperature of the outer wall of the cryogenic storage container, the thermal imaging camera further comprising camera software configured to generate a thermographic video of the external temperature; a display device displaying the thermographic video; and an alarm unit configured to activate an alert when the external temperature of the cryogenic storage container drops below a pre-selected trigger temperature.

VITRIFICATION STICK WITH BASKET END TIP
20210212312 · 2021-07-15 ·

The present invention is directed to a vitrification stick for use in the cryopreservation of biological materials, and may include a body having a first portion and a second portion, and a specimen end extending from the second portion of the body, and having a basket end tip formed thereon. The basket end tip may include a peripheral wall enclosing an interior region of the basket end tip, and the interior region may be further enclosed on a first side by a shell connected to the peripheral wall, and the interior region may be open on a second side in a direction towards the specimen end. The shell may include at least one slot formed therein.

Tube-array type nitrogen canister

A tube-array-type liquid nitrogen container includes a container body having a mouth; a tube array component received in the container body; and a top cap sealing the mouth from above. The top cap is rotatable in the mouth. The tube array component is composed of a plurality of holding tubes. The holding tube is opened at one end thereof, wherein the opening thereof faces the top cap. The top cap has at least one tube access passing therethrough. Each tube access is atop covered by a tube access cover. The tube-array-type liquid nitrogen container uses a tube-array component composed of the a plurality of holding tubes to store the freezing tubes, and is cooperated with the rotatable top cap and an external robotic arm, thereby improving space utilization and thermal insulation, effectively ensuring safety of the freezing tubes, and facilitating automatic storage of freezing tubes.