The invention provides certain nicotine salt co-crystals and provides novel polymorphic forms of certain nicotine salts. In particular, certain nicotine salt-co-crystals are described, including nicotine and two different coformers. The invention further provides methods of preparation and characterization of nicotine salts, co-crystals, and salt co-crystals. In addition, tobacco products, including smoking articles, smokeless tobacco products, and electronic smoking articles comprising nicotine salts, co-crystals, and/or salt co-crystals are also provided.

The invention relates to an oral nicotine formulation for use in the alleviation of nicotine craving, the formulation comprising a content of nicotine and a content of a pH regulating agent, wherein the formulation is designed for the content of nicotine to dissolve in the oral saliva within a period of less than 90 seconds upon oral administration, and wherein at least 40% by weight of the nicotine is absorbed through the oral mucosa.

The present invention provides an aerosol-generating material for use in aerosol generation, the aerosol-generating material comprising: about 10 to about 50 wt % caffeine; about 15 to about 60 wt % gelling agent; and about 10 to about 50 wt % aerosol-former material; wherein the wt % values are calculated on a dry weight basis.

The present invention provides an aerosol-generating material for use in aerosol generation, the aerosol-generating material comprising: about 10 to about 50 wt % caffeine; about 15 to about 60 wt % gelling agent; and about 10 to about 50 wt % aerosol-former material; wherein the wt % values are calculated on a dry weight basis.

A process is disclosed for incorporating additives into aerosol generating products. During the process, an additive is incorporated into an aerosol modifying composition. An aerosol generating filler is contacted with the aerosol modifying composition and the additive is uniformly incorporated into the substrate. In one application, a cannabidiol is incorporated into a tobacco filler or a cannabaceae filler.

A process is disclosed for incorporating additives into aerosol generating products. During the process, an additive is incorporated into an aerosol modifying composition. An aerosol generating filler is contacted with the aerosol modifying composition and the additive is uniformly incorporated into the substrate. In one application, a cannabidiol is incorporated into a tobacco filler or a cannabaceae filler.

A synthetic nutritional composition comprising a mineral for use to promote, support or optimise de novo myelination, in particular the de novo myelination trajectory, and/or brain structure, and/or brain connectivity, and/or intellectual potential and/or cognitive potential and/or learning potential and/or cognitive functioning in a subject, in particular a formula fed subject.

A synthetic nutritional composition comprising a mineral for use to promote, support or optimise de novo myelination, in particular the de novo myelination trajectory, and/or brain structure, and/or brain connectivity, and/or intellectual potential and/or cognitive potential and/or learning potential and/or cognitive functioning in a subject, in particular a formula fed subject.

A synthetic nutritional composition comprising a mineral for use to promote, support or optimise de novo myelination, in particular the de novo myelination trajectory, and/or brain structure, and/or brain connectivity, and/or intellectual potential and/or cognitive potential and/or learning potential and/or cognitive functioning in a subject, in particular a formula fed subject.

A nicotine pouched product is disclosed, the nicotine pouched product having a pouch composition and a pouch membrane enclosing the pouch composition, the pouch composition including at least one water-insoluble fiber, water in an amount of at least 15% by weight of the composition, and nicotine, wherein the pouch membrane comprises further nicotine in an amount of at least 15% by weight of a total content of nicotine in the pouched product.