Devices, systems, and methods for treating a heart of a patient may make use of one or more implant structures which limit a size of a chamber of the heart, such as by deploying a tensile member to bring a wall of the heart toward (optionally into contact with) a septum of the heart.

Described herein are methods and apparatuses for use in repair of a patient's tissue by connecting the tissue to the bone using a transosteal tunnel and anchor configured to pass through the transosteal tunnel. In particular, described herein are methods of repairing an anterior cruciate ligament (ACL) and torn meniscal root. These anchoring apparatuses and method of using them are particularly well suited for use with the low-profile suture passers described herein, since these suture passers may allow access to previously inaccessible regions of the knee (or other body regions).

An assembly includes a flexible fixation member, a suture, and a delivery device. The fixation member includes a body with two terminal ends. A suture passes through the flexible fixation member at various points along a length of the body such that portions of the fixation member are slidable relative to the suture and configurable to form a cluster within a surgical site. The delivery device includes a tubular member, an elongated inserter, and a trigger. The elongated inserter is slidably disposed within the tubular member. The inserter has a forked distal end configured to receive a portion of the flexible fixation member and the suture. The trigger is finger-engagable and fixedly coupled to the proximal end of the inserter. It is configured to advance and retract the inserter relative to the tubular member. The trigger includes a retention member for retaining a proximal end portion of the suture.

A device for treating a tissue defect including a grasper including a pair of arms movable between a tissue receiving configuration and a tissue gripping configuration, a needle extending longitudinally from a proximal end to a distal end and including a first lumen extending longitudinally therethrough, the needle slidably received between the arms so that the needle is movable between a non-extended configuration, in which the distal end of the needle is proximal the distal ends of the arms, and an extended configuration, in which the distal end of the needle is distal of the distal end of the arms, and a first suture element slidably housed within the first channel and deployable therefrom to be anchored in a first target tissue into which it is inserted, the first suture element including a first cross member attached to a distal end of a first suture.

An endoscopic gastric plication device includes an assembly able to co-operate with a handle provided with a control mechanism for actuating the assembly for placing and securing a staple around a fold in a stomach wall. The device includes: a mechanism for gripping/pulling a portion of a stomach wall arranged at the end of a manipulation rod adapted to be connected to the control mechanism, which mechanism is capable of being actuated by the control mechanism so as to grip the stomach wall and pull it to form a fold; a mechanism for guiding a staple around the fold in the stomach wall; at least one staple and a mechanism for pushing the staple into the guide mechanism, the staple being designed to pass through and form a loop around the fold while being guided by the guide mechanism; and a mechanism for pulling the looped end of the staple.

A system and method comprising an anchor assembly including an anchor and a locking element, a tensionable fixation member (e.g., surgical suture, tape, etc.), and a release member, wherein the anchor further comprises a first end, second end and anchor body. The anchor is configured for implantation into bone. One end of a tensionable fixation member is configured for attachment to a tissue to assist with fixation of the soft tissue. Once the anchor has been seated in bone, the second end of the tensionable fixation member is pulled through a one-way only passage in the body of the anchor. When the tensionable fixation member enters passage, it traverses past the locking element positioned within the anchor by bending or deflecting the locking element out of the way to permit passage of the tensionable fixation member while maintaining contact with the tensionable fixation member via elastic compression that results from the elastic bending or deflection of the locking element but prevents the tensionable fixation member from passing back. This continuous locking on the tensionable fixation member creates fixation security, allows for optimal tensioning, and prevents loosening in the opposite direction. The release member may be used to bend or deflect the locking element to loosen the tensionable fixation member to enable an operator to readjust the tension in the tensionable fixation member to the operator's liking.

A medical device for joining materials is provided. The device comprises a piercing element configured to penetrate materials to be joined. The piercing element is sufficiently sharp to penetrate materials to be joined and comprises a hollow interior along at least a portion of its length configured to distal advancement of a fastener therethrough; and an open tip through which the fastener can be pushed. The device can be used for fastening materials including tissue, synthetic mesh, and biologic mesh (e.g., ADM).

Devices, systems and methods for compressing, cutting, incising, reconfiguring, remodeling, attaching, repositioning, supporting, dislocating or altering the composition of tissues or anatomical structures to alter their positional or force relationship to other tissues or anatomical structures. In some applications, the invention may be used to used to improve patency or fluid flow through a body lumen or cavity (e.g., to limit constriction of the urethra by an enlarged prostate gland).

A system for treatment of tissue includes a fixation apparatus and a delivery tool releasably carrying the fixation apparatus. The fixation apparatus includes first and second anchors and an adjustable band connecting the anchors. The band includes a cinch line and a tether connected to one of the anchors. The delivery apparatus includes a body, a tubular shaft, a displacement rod within the tubular shaft, and an actuator.

A suture anchor driver with a tensioning mechanism. The suture anchor driver has a handle with a proximal end and a distal end. The handle has a recess with a shaft extending centrally therefrom. The suture anchor driver has a detent ring and a spool. The detent ring has a central aperture and one or more projections. The spool has a central aperture and is rotatable between first and second configurations. The spool has a plurality of protrusions extending from its side. The shaft extends through the central apertures in the detent ring and spool such that the projections of the detent ring are adjacent the protrusions extending from the spool. In the first configuration, one of the projections extends between two of the protrusions. In the second configuration, one of the projections is aligned with one of the protrusions.