A system for delivering a vascular implant into a body lumen including a vascular implant having a first engagement portion at a proximal portion and an elongated delivery member having a second engagement portion at a distal portion releasably engageable with the first engagement portion. An elongated member extends through the delivery member wherein in the extended position the elongated member extends into at least a portion of the implant to prevent release of the implant from the delivery member and in the retracted position the elongated member enables release of the implant from the delivery member.

A process and system for treating an aneurysm using one or more specifically shaped endovascular coils and an intrasaccular stent/retaining device that operates to hold the one or more endovascular coils or other embolization devices within the aneurysmal sac of the aneurysm, thereby obviating the patients' need for lifetime dual anti-platelet therapy.

This intrasacular aneurysm occlusion device includes a neck bridge with a closeable opening through which embolic material is inserted into an aneurysm sac. After the neck bridge has been expanded within the aneurysm sac, a catheter is inserted through the opening and embolic material is delivered through the catheter into the aneurysm sac. After the aneurysm sac has been filled with embolic material, the catheter is then withdrawn and the opening is closed so that embolic material does not escape out of the aneurysm sac.

Disclosed herein are medical devices comprising a single-lobed, thin-walled, expandable body and a flexible, elongated delivery device for treating saccular vascular aneurysms and occluding segments of blood vessels and other biological conduits. The expandable bodies may include gold and other metals that can be compressed, positioned in the lumen of an aneurysm, or other biological conduit and expanded. The external surface of the expandable bodies can be configured to promote local thrombosis and to promote the growth of tissue into and around the surface in order to reduce migration of the expandable body and to occlude and seal the aneurysm or biological conduit. For the treatment of saccular aneurysms, the expandable body may be deployed in combination with one or more coiled wires that contact both the wall of the aneurysm and the expandable body and exert force on the expandable body to aid in sealing the aneurysm neck.

An intravascular treatment system including an introducer sheath having an intentional friction zone along a section thereof imposing an intentional friction force on the outer surface of a catheter shaft slidable therein. The friction zone representing a non-straight (e.g., curved or bent) section of the introducer sheath and/or a section of the introducer sheath whose inner wall has a reduced inner diameter (e.g., fused heat shrink material). During intravascular treatment, sufficient axial force may be applied to overcome the imposed intentional friction force and advance the intravascular treatment device in a distal direction to a desired target site in the artery. Once properly positioned, the imposed intentional friction force ensures that the intravascular treatment device is maintained in place.

An implant including an open end and a pinched end can have a predetermined shape. When in the predetermined shape, the tubular braid can include a proximal inversion and two segments, and the braid can be composed of one or more wires. The first segment can extend from the open end of the tubular braid to the proximal inversion. The second segment can be at least partially surrounded by the open end and extend from the proximal inversion to the pinched end. The tubular braid can also include at least one corrugated fold. The one or more corrugated folds can be located within the first segment, second segment, or both. The corrugated folds can be configured to assist in anchoring the example device when in the implanted shape within an aneurysm in a similar manner to stent struts to help the tubular braid hold its shape.

A delivery system employs a hold-release structure to deploy an implant at a target site in the vasculature of a patient. The hold-release structure may include two or more grasping members configured to close and exert an inward clamping force to hold the implant when the grasping members are constrained in a tubular member. The grasping members can open when unconstrained allowing the implant to be released. Alternatively, the hold-release structure may include two or more radially expandable members configured to exert an outward radial force when constrained by the tubular member allowing the hold-release structure to hold the implant against the tubular member. The radially expandable members can be configured to create a friction force on the implant allowing the hold-release structure to move the implant relative to the tubular member.

An endovascular system employs a lever structure to deploy an embolic device at a target site in the vasculature of a patient. The endovascular system comprises an elongate tubular member provided with a lever structure and an elongate detachment wire to assert an effort to the proximal portion of a lever member outwardly, thereby generating a load to the distal portion of the lever member inwardly to allow the lever structure to engage and secure the embolic device. The elongate detachment wire is disengageable from the lever structure to remove the effort asserted to the proximal portion of the lever member, thereby removing the load off the distal portion of the lever member to allow the lever structure to disengage and release the embolic device.

Disclosed are implantable medical devices for the occlusion of a bodily lumen, cavity, vessel, or organ, as well as methods for manufacturing such occlusion devices, and methods for treating a subject using the occlusion devices. The devices generally include a wire having shape memory properties and a flexible membranous material disposed about the wire. Some embodiments include a lateral fringe on the membranous material. Some embodiments include a fluid capture cup affixed to the wire.

An implant (1) for the treatment of aneurysms (11), wherein the implant (1) has an elongated configuration navigable via a microcatheter (12) and a secondary configuration which it assumes upon release from the microcatheter (12). The implant (1) forms an open, unrolled structure (2) extending from proximal to distal, said implant being built up of a plurality of struts (3) forming adjacent cells (4), and with at least a part of said cells (4) being provided with membranes (6) filling the cells (4), and with the secondary structure comprising an at least partial rolling up of the open, unrolled structure (2) axially and radially relative to the longitudinal axis of the implant (1) and resulting in the formation of a spherical structure. The implant (1) proposed by the invention is suitable to adapt to the inner wall of an aneurysm (11) and to fill an aneurysm (11) almost completely.