A system for treating cardiac dysfunction can include an expandable device for insertion into a heart, a foot configured to contact a portion of the heart, a support frame, and a membrane coupled to the support frame. The support frame can include a plurality of radially expandable struts each having a first free end configured to extend beyond the foot and a second end coupled to the foot. The plurality of radially expandable struts can include a plurality of staggered stops, and each of the stops can be positioned on a respective one of the struts proximal to the first free end of the respective one of the struts. Method for treating cardiac dysfunction can include implanting the systems described herein into a chamber of the heart.

A non-occlusive device is provided that includes a coilable section and a docking section. When deployed from a microcatheter within a wide-neck vascular aneurysm, the coilable section is configured to become coiled into a coil defining a sequence of concentric loops, and to bridge a neck of the aneurysm so as to at least partially cover an orifice of the aneurysm, when in use. The docking section is configured to be deployed from the microcatheter within the aneurysm. The docking section extends distally from an outermost one of the concentric loops of the coil, and is shaped so as to define one or more concentric loops having an outer diameter less than an outer diameter of the concentric loops of the coil. The docking section is configured to anchor, stabilize, and/or assist with positioning of the device within the aneurysm. Other embodiments are also described.

Devices and methods for treating vascular defects, such as, for example, balloon-type aneurysms, are described herein. In one embodiment, an apparatus includes an insertion portion and an expandable implant. The expandable implant is configured to be deployed in an aneurysm and is coupled to the insertion portion. The expandable implant has a first portion and a second portion coupled to the first portion. The expandable implant is movable between a first configuration in which the first portion and the second portion are substantially linearly aligned and a second configuration in which the second portion at least partially overlaps the first portion.

A device for placement in vessels, appendages, and openings in a body, the device comprising: a frame having a plurality of elongate members, the frame including: a substantially uniform proximal end of the frame having (i) a center frame portion arranged at the proximal end and (ii) face portions of the plurality of elongate members extending from the center frame portion and including a curved pattern arranged substantially within a first plane approximately perpendicular to a longitudinal axis of the frame; a body portion; a membrane coupled to at least the substantially uniform proximal end of the frame; and a coating arranged on at least a portion of the membrane configured to minimize the thrombogenic response of blood contact with the membrane.

Disclosed are implantable medical devices for the occlusion of a bodily lumen, cavity, vessel, or organ, as well as methods for manufacturing such occlusion devices, and methods for treating a subject using the occlusion devices. The devices generally include a wire having shape memory properties and a flexible membranous material disposed about the wire. Some embodiments include a lateral fringe on the membranous material. Some embodiments include a fluid capture cup affixed to the wire.

Embolic coil implant systems and methods whereby coils are mechanically detachable are disclosed. The coils include a retention element that may be releasably retained within the distal end of an implant tool. The implant tool may include a fulcrum configured to engage a first filament and prevent the release of the coil when the first filament is engaged. Alternatively, an urging means and aperture may be disposed within the sidewall of the implant tool, and a first filament may, in conjunction with the aperture and sidewall, releasably retain the coil until the first filament is withdrawn. The implant tool may also include an alignment member for aligning the first filament.

The present disclosure is related to an occlusion device having a mesh structure. The occlusion device configured to transition between a two-dimensional configuration and a three-dimensional configuration. In the two-dimensional configuration and at rest, the occlusion device is flat or planar. In the three-dimensional configuration, the occlusion device defines an internal volume.

According to an embodiment, an embolic apparatus includes: a main body portion extending in a longitudinal direction; a plurality of first frame portions foldably connected to the main body portion; a plurality of second frame portions foldably connected to an end opposite to the other end of the main body portion connected to the plurality of first frame portions; and a blocking film portion connecting the plurality of first frame portions and covering the first frame portion, wherein the first frame portion and the second frame portion extend in directions away from each other.

An medical implantable occlusion device (100) is disclosed having a collapsed state and an expanded state and comprising a braiding (101) of at least one thread, and a distal end (102) comprised of said braiding. The distal end comprises loops (103, 104, 204, 304) formed by loop strands (105, 106, 206, 306) of the at least one thread, wherein, at least in said expanded state, each loop strand has a curved shape and extends away from a centre point (117) of the distal end, whereby an apex point (107, 108, 208, 308) of each of the loop strands corresponds to the turning point of the curved shape and to the point of each of the loop strands being arranged closest to the centre point. At least one of the loop strands is displaced from the centre point by a centre distance (109, 110, 210, 310), and the apex point lie at a distance from a periphery (113) of the distal end.

A vaso-occlusive device, includes: a vaso-occlusive structure configured for implantation in an aneurysm sac, the vaso-occlusive structure having a delivery configuration when restrained within a delivery catheter and having a deployed configuration when released from the delivery catheter into the aneurysmal sac, at least a portion of the vaso-occlusive structure being composed of a AuPtW (gold-platinum-tungsten) alloy; wherein the AuPtW alloy comprises platinum within a range between 25% and 40% by weight, and wherein the AuPtW alloy comprises tungsten within a range between 0.01% and 10% by weight.