Devices used to restrict flow within a blood vessel are disclosed. Devices within the scope of this disclosure include a braided lattice of nitinol wires that form self-expanding enclosures of an embolic structure. The devices may further include embolic particles disposed within the enclosures. Methods of deploying the devices with the embolic particles are disclosed. Methods of manufacturing the devices with the embolic particles disposed within the enclosures are disclosed.

A system for delivering a vascular implant into a body lumen including a vascular implant having a first engagement portion at a proximal portion and an elongated delivery member having a second engagement portion at a distal portion releasably engageable with the first engagement portion. An elongated member extends through the delivery member wherein in the extended position the elongated member extends into at least a portion of the implant to prevent release of the implant from the delivery member and in the retracted position the elongated member enables release of the implant from the delivery member.

An embolization device (10) for promoting clot formation in a bodily lumen and having a contracted delivery configuration and an expanded deployed configuration. The embolization device (10) has a stem (30) and a plurality of flexible bristles (20) extending radially outwardly from the stem (30), the stem (30) comprising: a first wire element (31); a second wire element (32); a tubular interconnect (33) having a lumen and connecting the first wire element (31) to the second wire element (32), the first wire element (31) and the second wire element (32) being disposed within the lumen of the tubular interconnect (33); and a reinforcing sleeve (50) being fixedly disposed over at least part of the tubular interconnect (33) and fixedly disposed over at least part of one or both of the first wire element (31) and the second wire element (32). The reinforcing sleeve (50) has a lower stiffness than the tubular interconnect (33).

Apparatus and methods are provided for occluding blood vessels and other anatomical structures. Occlusion devices are delivered percutaneously and extraluminally through a small gauge needle and include expandable elements that are deployable on opposite sides of a target vessel to be occluded. When positioned about the vessel the elements are expanded and brought together to compress and occlude the vessel. Embodiments include those adapted for temporary as well as permanent use.

An endovascular system employs a lever structure to deploy an embolic device at a target site in the vasculature of a patient. The endovascular system comprises an elongate tubular member provided with a lever structure and an elongate detachment wire to assert an effort to the proximal portion of a lever member outwardly, thereby generating a load to the distal portion of the lever member inwardly to allow the lever structure to engage and secure the embolic device. The elongate detachment wire is disengageable from the lever structure to remove the effort asserted to the proximal portion of the lever member, thereby removing the load off the distal portion of the lever member to allow the lever structure to disengage and release the embolic device.

An medical implantable occlusion device (100) is disclosed having a collapsed state and an expanded state and comprising a braiding (101) of at least one thread, and a distal end (102) comprised of said braiding. The distal end comprises loops (103, 104, 204, 304) formed by loop strands (105, 106, 206, 306) of the at least one thread, wherein, at least in said expanded state, each loop strand has a curved shape and extends away from a centre point (117) of the distal end, whereby an apex point (107, 108, 208, 308) of each of the loop strands corresponds to the turning point of the curved shape and to the point of each of the loop strands being arranged closest to the centre point. At least one of the loop strands is displaced from the centre point by a centre distance (109, 110, 210, 310), and the apex point lie at a distance from a periphery (113) of the distal end.

Disclosed are implantable medical devices for the occlusion of a bodily lumen, cavity, vessel, or organ, as well as methods for manufacturing such occlusion devices, and methods for treating a subject using the occlusion devices. The devices generally include a wire having shape memory properties and a flexible membranous material disposed about the wire. Some embodiments include a lateral fringe on the membranous material. Some embodiments include a fluid capture cup affixed to the wire.

Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.

A device for occluding a patient's left atrial appendage (LAA) device includes a self-expanding closure disc and an anchor. The self-expanding closure disc has an atrial side, an appendage side, and a peripheral edge configured to engage tissue on both an atrial side and an appendage side of an opening between the left atrium and the left atrial appendage. The self-expanding anchor extends from the appendage side of the self-expanding closure disc, and an annular sealing skirt extends about at least a portion of the appendage side of the self-expanding closure disc. the annular sealing skirt is more compliant than the self-expanding closure disc to seal over the left appendage side of the opening after implantation of the device in the LAA.

Implantable therapeutic devices and methods for endovascular placement of devices at a target site, such an opening at a neck of an aneurysm, are disclosed. Selected embodiments of the present technology have closures that at least partially occlude the neck of an aneurysm to stabilize embolic or coagulative treatment of the aneurysm.