In various aspects, the invention includes an embolic device for use in treating a vascular disorder that can include a flexible structure including a series of alternating narrow portions and link portions. Each link portion can include two struts that substantially circumscribe an opening in at least one plane. In some cases, the embolic device further includes a link portion coil disposed over each of the two struts of at least one link portion.

A vascular remodeling device has a plurality of sections, sized for deployment in a blood vessel, that is radially expandable from a collapsed state to an expanded state. Each section has a plurality of interconnected struts that define a waist, a proximal face, and a distal face. Each face comprises (i) a plurality of distal strut portions extending proximally from a distal side of the face, (ii) a plurality of proximal strut portions extending distally from a proximal side of the face, and (iii) a plurality of sub-struts, wherein, from each proximal strut portion, two of the sub-struts each extend to a different one of the distal strut portions.

A vaso-occlusive device is constructed out of dissimilar metallic materials that are in contact or otherwise in close proximity with one another, thereby causing the device to undergo galvanic corrosion when exposed to an electrolytic medium, such as blood or other body fluid, wherein one of the dissimilar metallic materials is zirconium or zirconium alloy to create a corrosive product including zirconia having a relatively high hardness, a relatively high fracture toughness, and a relatively high stability when the device is implanted in a vasculature site, such as an aneurysm.

Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. The device may have a thromboresistant cover at a proximal end. The frame may have recapture struts inclining radially outwardly from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame and into the foam to engage tissue.

An endovascular device, including an elongated flexible sheath defining a lumen with an inner opening sized for enabling selective advancement of an endovascular instrument therethrough, the sheath having at least a first region and a second region; an electrode within the first region of the sheath; and a constrictor associated with the first region of the sheath, the constrictor being configured, while at least the first region and the second region of the sheath are positioned within a body and in response to an input received from outside the body, to reversibly narrow the lumen of the sheath in an area adjacent the electrode to thereby bring the electrode into contact with an adjacent portion of the endovascular instrument.

A delivery device (1) for an endoprosthesis (2). The endoprosthesis (2) is preferably an endoprosthesis for treating an aneurysm. The delivery device (1) comprises an outer sheath (3) and an inner tube (4). The inner tube (4) is arranged within the outer sheath (3) and at least one restraining tube (5, 30). The restraining tube (5, 30) is for holding the endoprosthesis (2) in a compressed configuration. The restraining tube (5, 30) is arranged between the outer sheath (3) and the inner tube (4). The outer sheath (3), the inner tube (4) and at least one restraining tube (5, 30) are coaxial. The restraining tube (5, 30) includes at least one axial elongation (6) extending from a distal end portion of the restraining tube. The at least one axial elongation (6) is adapted to be laced through portions of the endoprosthesis (2).

The invention relates to an endoprosthesis (1), in particular a vascular or cardiac endoprosthesis (1), having a body (2) and also one or more thrombogenic elements (3) that are fixed to the endoprosthesis (1) and that are able to extend a distance away from the body outside the latter. The endoprosthesis comprises means (33) for selectively retaining the thrombogenic elements near the body (2). The release of the one or more thrombogenic elements, after the endoprosthesis has been fitted in place by a conventional method via a sheath, promotes thrombosis.

Provided is a device for delivery into a body lumen having a longitudinally extending stem and a plurality of bristles extending generally radially outwardly from the stem. The device includes at least two different groups or types of bristles.

Devices and methods for treating vascular defects, such as, for example, balloon-type aneurysms, are described herein. In one embodiment, an apparatus includes an insertion portion and an expandable implant. The expandable implant is configured to be deployed in an aneurysm and is coupled to the insertion portion. The expandable implant has a first portion and a second portion coupled to the first portion. The expandable implant is movable between a first configuration in which the first portion and the second portion are substantially linearly aligned and a second configuration in which the second portion at least partially overlaps the first portion.

An embolisation device (300) for promoting clot formation in a bodily lumen, the embolisation device having a collapsed delivery configuration and an expanded deployed configuration, the embolisation device comprising a plurality of flexible bristles (220), wherein at least one of the plurality of bristles comprises a twisted portion (350), the at least one twisted portion securing the plurality of bristles to one another, and wherein the plurality of bristles extend at least radially outwardly from the at least one twisted portion.