The invention relates to an endoprosthesis (1), in particular a vascular stent or a heart stent, comprising at least one body (3) part. At least one area (5,6) of an outer surface, preferably the whole outer surface, of the at least one body part (3) is provided with thrombogenic fibers (2). The invention further relates to methods of manufacturing endoprostheses (1).

A pulmonary artery flow restrictor system includes a funnel shaped membrane with a proximal base, a restrictive distal opening which is stretchable to larger sizes, an internal strut structure, and an external stent structure.

The present disclosure relates to delivery devices and interventional devices configured to enable monitoring of pressure and other hemodynamic properties before, during, and/or after a cardiac procedure. A guide catheter includes a routing lumen or a routing groove for routing a sensor wire to a desired location during a cardiac procedure. A guide catheter includes one or more pressure sensors positioned to provide desired pressure measurements when the guide catheter is deploying an interventional device. An interventional device may also include one or more associated sensors for providing hemodynamic information before, during, and/or after deployment.

A deployable occlusion device for filling an aneurysm. The occlusion device includes a support structure, for example a wire or otherwise elongate structure. The occlusion device also includes a mesh component having a porosity. The mesh component has a first end portion and a second end portion. The first end portion of the mesh component is attached to the support structure and the second end portion of the mesh component is a free end. The mesh component extends from the support structure.

A system, device and method for left atrial appendage occlusion detection is disclosed. The system for occlusion detection comprises a sheath; a delivery system comprising: a delivery catheter extending between a proximal end and a distal end; and a handle coupled to the proximal end of the delivery catheter; a medical tool coupled to a distal end of the delivery catheter at a target location within a portion of an organ of a patient, the medical device comprising a hub including a bore defining an axis, an occluder portion coupled to the hub and an anchor portion extending between a first end and a second end; at least one pressure sensor configured to measure a pressure of the target cavity while blood is suctioned form inside the left atrial appendage; and at least one processor configured to process the pressure measurement acquired from the at least one pressure sensor.

An embolisation device (10) for promoting clot formation in a bodily lumen (L) and having a collapsed delivery configuration for delivery of the embolisation device (10) into, and retrieval of the embolisation device (10) from, the bodily lumen (L) and an expanded deployed configuration for anchoring the embolisation device (10) in the bodily lumen (L). The embolisation device (10) comprises a tubular cage (20) having a collapsed delivery configuration and an expanded deployed configuration. The embolisation device further comprises an embolisation member (30) disposed in the tubular cage (20), the embolisation member (30) comprising a stem (31) and a plurality of flexible bristles (32) extending outwardly from the stem, the plurality of flexible bristles having a collapsed delivery configuration and an expanded deployed configuration. The embolisation device (10) is configured such that as the tubular cage (20) is transitioned from its expanded deployed configuration to its collapsed delivery configuration the plurality of flexible bristles (32) is urged by the tubular cage (20) from the expanded deployed configuration of the flexible bristles (32) to the collapsed delivery configuration of the flexible bristles (32).

An embolisation device (100) for promoting clot formation in a bodily lumen (170), comprising a stem (110) and a plurality of flexible bristles (120) extending outwardly from the stem, the bristles having a contracted delivery configuration and an expanded deployed configuration in which the bristles extend at least radially outwardly from the stem to anchor the device in the lumen. The embolisation device comprises a flow restrictor configured to restrict flow through the bodily lumen. The flow restrictor comprises: a membrane support (135) having a contracted delivery configuration and an expanded deployed configuration and comprising a self-expanding mesh extending at least radially outwardly from the stem; and an occluding membrane (130) mounted on the membrane support (135). The occlusion rate of the occluding mesh membrane is greater than that of the membrane support. The flow restrictor is attached to the stem at a first longitudinal end, the flow restrictor further comprising an open second longitudinal end. The occluding membrane is configured to restrict flow through the lumen when the device is deployed and the membrane support is in the expanded deployed configuration.

A vessel occluder used to occlude blood flow within the vasculature is described. The vessel occluder can include an expandable mesh portion having a flexible membrane that expands within a cavity of the expandable mesh portion. When expanded, the flexible membrane blocks blood passage through the mesh portion.

An atrial appendage closure device is provided that includes an insertion rod having a first end and a second end. An occluding member having an outer surface and an inner surface is connected to the first end of the insertion rod. The occluding member is moveable between a retracted position and a deployed position such that, in the deployed position, the occluding member is configured to provide a seal between a left atrial appendage and a left atrium of a heart. An anchoring member is further connected to the insertion rod and is configured to slide along the insertion rod to secure the device to a wall of a left atrial appendage. Methods for occluding a left atrial appendage that make use of the closure devices are also provided.

Embodiments of the present invention provide an improved vascular occlusion device for occlusion of a passageway, cavity, or the like. According to one embodiment, a medical device for occluding a left atrial appendage is provided. The medical device includes a first portion having at least one plane of occlusion that is configured to be positioned outside of the left atrial appendage, and a second portion having at least one plane of occlusion that is configured to be at least partially positioned within a cavity defined by the left atrial appendage.