Systems and methods for determining surgical system settings during a surgical procedure are disclosed. The surgical systems comprise of a control system, a means for tissue removal, sensing capabilities and machine learning application(s). The sensing capabilities and machine learning application(s) are configured to determine type and/or properties of the removed tissue and to predict preferred surgical settings for optimized removal and surgical outcomes. The learning machine application(s) communicates these preferred settings to a surgical control system.

An ultrasound catheter with a lumen for fluid delivery and fluid evacuation, and an ultrasound source is used for the treatment of intracerebral or intraventricular hemorrhages. After the catheter is inserted into a blood clot, a lytic drug can be delivered to the blood clot via the lumen while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the lumen.

The present disclosure relates generally to the use of medical devices for the treatment of vascular conditions. In particular, the present disclosure provides devices and methods for using electrically-induced pressure waves to disrupt vascular blockages. The present disclosure not only provides devices and methods for using electrically-induced pressure waves to disrupt vascular blockages, but the present disclosure also provides devices and method for assisting the guidewire in penetrating an occlusion, devices and method for using a sealable valve in the tip of the balloon catheter to reduce the overall size and diameter of the balloon catheter, thereby allowing the balloon catheter to penetrate smaller size blood vessels and devices. Given the persistence of coronary artery disease (CAD) and peripheral artery disease (PAD), there remains a need for improved therapeutic methods designed not only to reduce vascular blockages in the short term, but also to prevent future complications such as restenosis.

An interventional medical device, and method of manufacturing the same, is provided to reduce risk to the patient of a fracture of the interventional medical device. At least one portion of the interventional medical device that is subject to fracture and migration within a patient is identified. A membrane is applied over each portion of the interventional medical device that is subject to fracture and migration, such that any fractured portion of the interventional medical device is tied together by the membrane.

Embodiments are directed to electro-hydraulically actuated lithotripters and methods for fragmenting stones using such lithotripters. In an embodiment, a lithotripter apparatus for fragmenting at least one stone in a body is disclosed. The lithotripter apparatus includes a chamber configured to contain an electro-conductive fluid, which includes a proximal end wall and a distal end wall spaced from the proximal end wall. A chisel is coupled to the chamber and located at least proximate to the distal end wall. A proximal electrode is located at least partially in the chamber. A distal electrode is located at least partially in the chamber and spaced from the proximal electrode. Responsive to an effective voltage applied between the proximal and distal electrodes, the proximal and distal electrodes are configured to electrically discharge into the electro-conductive fluid to generate shock waves in the chamber that accelerate the chisel toward the at least one stone.

A catheter for intraluminal lithotripsy including an outer wall, at least one balloon extending from the outer wall, the balloon having a first portion, a second portion proximal of the first portion and an intermediate portion between the first and second portions such that a transverse dimension of the intermediate portion is less than a transverse dimension of the first and second portions. The catheter includes a first lumen, at least one energy emitter mounted on the balloon for emitting energy to break down or soften calcium and a connector connecting the at least one energy emitter to an external energy source, the connector extending through the catheter.

In one aspect, the present disclosure pertains to ultrasonic treatment devices that comprise: (a) a flexible elongate body having a proximal end and a distal end, the flexible elongate body being configured for insertion to a target site within a patient; (b) an effector assembly disposed at the distal end of the flexible elongate body, the effector assembly comprising a piezoelectric transducer and an end effector; and (c) flexible electrical conductors in electrical communication with the piezoelectric transducer, the flexible electrical conductors extending along a length of the flexible elongate body, wherein transference of electrical energy to mechanical motion takes place via the piezoelectric transducer at the target site. Other aspects of the present disclosure pertain to systems employing such ultrasonic treatment devices and methods of treatment using such ultrasonic treatment devices.

A catheter for intravascular lithotripsy including an outer wall, at least one torus balloon mounted on the outer wall, a first lumen extending therein, and at least one energy emitter for emitting energy to break down calcium. The at least one energy emitter is mounted on the balloon and a connector connects the energy emitter to an external energy source, the connector extending through the catheter. The balloon has a passageway for blood flow therethrough.

The present disclosure pertains to assemblies, devices and systems for shockwave generation and to methods of using the same.

The invention provides a device for generating shock waves. The device may comprise an elongated tube and a conductive sheath circumferentially mounted around the elongated tube. The device may further comprise first and second insulated wires extending along the outer surface of the elongated tube. A portion of the first insulated wire is removed to form a first inner electrode, which is adjacent to a first side edge of the conductive sheath. A portion of the second insulated wire is removed to form a second inner electrode, which is adjacent to a second side edge of the conductive sheath. Responsive to a high voltage being applied across the first inner electrode and the second inner electrode, a first shock wave is created across the first side edge and the first inner electrode, and a second shock wave is created across the second side edge and the second inner electrode.