A distal aspiration catheter comprises catheter body having a central lumen and at least one luminal channel. An aspiration source is configured to attach to a proximal end/luer hub of the central lumen. Each luminal channel includes one mandrel and a distal portion of the mandrel extends into a distal portion in the central lumen. When the aspiration source is activated, a clot/emboli lodged in a blood vessel is partially ingested into the distal portion of the central lumen. The distal portion of the mandrel can move into the partially ingested clot to induce clot fatigue. The fatigued clot can be removed completely by a single pass of the distal aspiration catheter.

An assembly insertable into a lumen of a patient including a motor housing having a motor contained therein, a motor shaft extending from the motor, a first coupler positioned at the motor shaft having a first magnet positioned therein adjacent a distal end, a rotational wire, and a second coupler positioned at a proximal portion of the thrombectomy wire. The second coupler has a second magnet positioned therein adjacent a proximal end. The second coupler is engageable with the first coupler to operably connect the rotational wire to the motor shaft, the first and second magnets providing an attractive force between the first and second couplers to maintain a connection of the first and second couplers so rotation of the first coupler rotates the second coupler.

The disclosure provides for an adjustable catheter system with isovolumetric suction and restoration of fluid for the removal of a thrombus and a method of use thereof. The catheter system includes an inner catheter and an outer sheath surrounding at least a portion of the inner catheter. The inner catheter may include at least three lumina extending from the proximal end to the distal end of the inner catheter, at least one infusion fenestration along the infusion segment, and a distal encapsulation balloon at the distal end. The outer sheath may include at least three lumina extending from the proximal end to the distal end of the outer sheath and a proximal encapsulation balloon at the distal end. The catheter system may further include an agitator for mechanical morcellation of the thrombus.

The present disclosure includes a calculi fracture device having an acoustic transducer for transferring acoustic energy via a primary fragmentation probe to fracture a calculi mass into calculi fragments, an evacuation tube connecting the probe to a pressure source, and a secondary fragmentation device located in an evacuation pathway extending along the fragmentation probe and the evacuation tube to further break up the calculi fragments to inhibit clogging at a more proximal location in the evacuation pathway. A method of inhibiting clogging of a calculi fracture device can include receiving, from a primary fragmentation device, fragments of a calculi mass along a passage of a evacuation pathway of the calculi fracture device and further breaking up the calculi fragments along the passage of the evacuation pathway at a location that is more proximal to a primary fragmentation location.

A uterine fibroid tissue removal device includes an inner tube disposed within an outer tube and configured to be translated and rotated relative to the outer tube, and a separately formed unitary distal tip member attached to a distal end of the inner tube, such that the distal tip member translates and rotates relative to the outer tube along with the inner tube, wherein a distal facing open cutting end of the distal tip member in fluid communication with an axial lumen of the distal tip member translates across a tissue resection window in a sidewall of the outer tube so as to sever tissue extending therethrough, the distal tip member axial lumen being in fluid communication with an axial lumen of the inner tube, wherein an outer diameter of the distal tip member is greater than an outer diameter of the inner tube.

A neurovascular catheter extension segment is provided, such as for distal neurovascular access or aspiration. The neurovascular catheter extension segment includes 1) an elongate flexible control wire having a proximal end and a distal end and 2) a tubular extension segment having a side wall defining a central lumen carried by the distal end of the control wire. The side wall of the tubular extension segment includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, and an outer jacket surrounding the helical coil. The extension segment may be introduced into the proximal end of a neurovascular catheter and advanced distally to extend beyond the catheter and thereby extend the reach of the catheter.

A medical device designed to be inserted into a lumen of a living body so as to block a flow of fluid in the lumen of the living body. The medical device includes: a long shaft part; an expandable part; and a covering part. The expandable part is an elastically deformable cylindrical body, and the cylindrical body having a proximal part connected to the shaft part. The covering part takes on a cylindrical shape and is flexible and deformable independently of the expandable part, and the cylindrical shape has a proximal part connected to a proximal part of the expandable part or connected to the shaft part located at a proximal side with respect to the expandable part. The covering part defines a space in the radial direction between a distal side end part of the cylindrical shape and the expandable part.

Provided is a medical device designed to be inserted into a lumen of a living body, the medical device including: a long shaft part; and a cylindrical hollow body. The shaft part has a center axis at position which differs from a center axis of the hollow body on a cross section perpendicular to the center axis of the shaft part. The hollow body has a housing part extending along the center axis of the hollow body, the hollow body being a groove depressed from an outer peripheral surface to an inner peripheral surface or a slit penetrating from an outer peripheral surface to an inner peripheral surface. The shaft part is positioned between inner surfaces facing from the outer peripheral surface to the inner peripheral surface in such a way that at least a portion of the shaft part constitutes the slit or the groove of the housing part.

A capturing unit provided on a distal end of a second tube can be deformed into a contracted state and an expanded state, in which the capturing unit is deployed to form a capturing chamber. The capturing chamber has an opening area decreased as it goes from a distal end opening of the capturing chamber toward a proximal end opening of the capturing chamber. A third tube rotatable relative to the second tube and a cutting unit provided on a distal end of the third tube for cutting a foreign substance are arranged in a second lumen. In the expanded state of the capturing unit, the cutting unit is arranged more toward the proximal end opening of the capturing chamber than the distal end opening.

An atherectomy device for removing deposits such as plaque from an interior of a vessel including an outer member and a rotatable shaft positioned for rotational movement within the outer member. The outer member is fixed axially. A rotatable tip is mounted to the distal region of the rotatable shaft for rotation about its longitudinal axis upon rotation of the shaft. The rotatable shaft includes a guidewire lumen for receiving a guidewire to enable over the wire insertion of the device.