Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain. The modulation may be performed by a neuromodulation device (e.g., an energy delivery device).

System and methods for channeling a path into bone include a trocar having a proximal end, distal end and a central channel disposed along a central axis of the trocar. The trocar includes a distal opening at or near the distal end of the trocar. The system includes a curved cannula sized to be received in the central channel, and having a curved distal end configured to be extended laterally outward from the distal opening in a curved path extending away from the trocar. The curved cannula has a central passageway having a diameter configured allow a probe to be delivered through the central passageway to a location beyond the curved path.

Systems for the minimally invasive repair, stabilization and/or fixation of a fractured bone, such as a rib, are disclosed. The systems include one or more rods/support members that are designed to extend along a dimension of a bone being repaired and secure the fractured bone. The support members can be photodynamic and are formed using an expandable member that is filled with a light-sensitive liquid that is cured to form the rigid support member. Two or more clamps are used to secure the support member(s) to the rib or other bone. Minimally invasive surgical methods for securing the systems to a fractured bone are also disclosed.

A method of stabilizing a first vertebra and a second vertebra includes implanting a first bone anchor into the first vertebra, implanting a second bone anchor into the second vertebra, connecting a first anchor connection instrument to the first anchor, connecting a second anchor connection instrument the second anchor, positioning a cement delivery tube into a passage provided through the first anchor, delivering bone cement from a bone cement delivery system coupled to the bone cement delivery tube through the passage in the first anchor to the first vertebra, removing the cement delivery tube from the first anchor connection instrument and the first anchor, connecting the cement delivery tube to second anchor connecting instrument connected to the second anchor, delivering bone cement through a passage in the second anchor to the second vertebra, connecting a spinal connection element to the first anchor and the second anchor.

Biomaterials, in particular bone foams, a process for preparing such materials as well as an applicator for applying the biomaterials directly to the patient's application site, and the use of a composition comprising water, a surfactant and a propellant in the preparation of a bone foam for the preparation of a calcium phosphate foam wherein the foam is obtainable by the mixture of at least two phases, a first phase comprising water and optionally a propellant, a second phase comprising one or more sources for calcium and/or phosphate, and wherein the foaming is performed during the mixture of the at least two phases to provide an improved calcium phosphate foam, process for the preparation of a calcium phosphate foam, use of a composition, solid state structure, calcium phosphate cement foam and bone foam applicator.

A shoulder implant for simulating a naturally occurring bursa proximal to or in lieu of a subacromial bursa, the shoulder implant comprising: an expandable member expandable to a size and/or a shape sufficient to fill a space beneath an acromion and/or a coracoid process of the shoulder, the space defines a filled volume less than a maximal volume occupied by the expandable member if fully expanded; and an amount of filler for filling the expandable member to the filled volume, such that, when implanted, the expandable member is configured to cushion and facilitate motion between a tendon and/or ligament of a rotator cuff, and a bone part in the shoulder.

System and methods for channeling a path into bone include a trocar having a proximal end, distal end and a central channel disposed along a central axis of the trocar. The trocar includes a distal opening at or near the distal end of the trocar. The system includes a curved cannula sized to be received in the central channel, and having a curved distal end configured to be extended laterally outward from the distal opening in a curved path extending away from the trocar. The curved cannula has a central passageway having a diameter configured allow a probe to be delivered through the central passageway to a location beyond the curved path.

A bone anchor includes a shank having a free end, a longitudinal axis, a channel extending axially through the shank to the free end, the channel having a first width, and at least one opening extending through a wall of the shank, and a narrowing member including an elastically deformable portion configured to extend into the channel at or near the free end. The narrowing member is adjustable from a first configuration where the deformable portion defines an opening with a width smaller than the first width to restrict a substance from exiting through the free end, to a second configuration where the deformable portion is deformed radially outwardly to define an opening with a width that is at least the first width, while at least a portion of the shank positioned at a same axial height as the deformable portion maintains a constant outer width.

The invention relates to a delivery system, device and method for delivering biomaterials for fracture fixation (including augmented fixation), in particular, for delivery of bone cements. The mixing system ensures the biomaterial only commences setting upon extrusion from the mixer, cannula or during injection through an appropriate internal fracture fixation device, allowing for rapid closing by the surgeon. The system also permits the surgeon to cease injecting the cement for an extended period of time before continuing the injection in another area using the same cartridge, through the simple removal of one mixer and attaching another in its place. The invention also provides a method of delivery of biomaterials to a desired implantation site.

A method is provided for stabilizing a bone. A plate is positioned over a bone. The bone plate has a polyaxial screw hole with a spherically curved seat. A bone hole is formed beneath the screw hole. A screw having a head with a spherical outer surface, and a threaded shaft with an internal cannula and a plurality of fenestrations is provided. The screw is driven through the first screw hole and into the bone hole until the outer surface of the head is supported by the spherically curved screw seat. A syringe provided with a needle is inserted into the internal cannula of the shaft of the screw. The syringe includes a bone injectable material that is injected through the needle, into the internal cannula, and out of at least one fenestration into the bone. After injection, the needle is removed from the screw shaft.