Apparatus, systems, and methods for treating PKD by providing access to a patient's renal pelvis of a kidney to treat renal nerves embedded in tissue surrounding the renal pelvis. Access to the renal pelvis may be via the urinary tract or via minimally invasive incisions through the abdomen and kidney tissue. Treatment is effected by exchanging energy, typically delivering heat or extracting heat through a wall of the renal pelvis, or by delivering active substances to ablate a thin layer of tissue lining at least a portion of the renal pelvis to disrupt renal nerves within the tissue lining of the renal pelvis

A treatment device includes a flexible sheath; a control wire that can move axially within the flexible sheath; a first treatment member connected to a distal end of the control wire; a second treatment member connected to a distal end of the first treatment member; and a protection member that covers the second treatment member depending on the mode of operation. When the treatment device is in a first treatment mode, the second treatment member projects from a distal end of the protection member. When the treatment device is in a second treatment mode, the first treatment member projects from the distal end of the flexible sheath, and the protection member covers the second treatment member.

Lysing surgical instruments and related systems and methods. In some embodiments, the instrument may comprise a lysing tip comprising at least one bead. The at least one bead may comprise an at least substantially electrically non-conductive surface and at least one lysing member defining at least one lysing segment extending within a recess defined, at least in part, by the at least one bead. The at least one bead may also protrude both distally and proximally relative to the at least one lysing member.

Apparatus, systems, and methods provide access to the renal pelvis of a kidney to treat renal nerves embedded in tissue surrounding the renal pelvis. Access to the renal pelvis may be via the urinary tract or via minimally invasive incisions through the abdomen and kidney tissue. Treatment is effected by exchanging energy, typically delivering heat or extracting heat through a wall of the renal pelvis, or by delivering active substances to ablate a thin layer of tissue lining at least a portion of the renal pelvis to disrupt renal nerves within the tissue lining of the renal pelvis

Ablation systems and methods of the present disclosure are directed toward delivering pulsed radiofrequency (RF) energy to target tissue. The pulsations of the RF energy, combined with cooling at a surface of the target tissue, can advantageously promote local heat transfer in the target tissue to form lesions having dimensions larger than those that can be safely formed in tissue using non-pulsed RF energy under similar conditions.

Systems and methods for facilitating assessment of a nature of contact between an electrode assembly of an ablation catheter and viable body tissue are disclosed herein. In some embodiments, a method comprises obtaining a first detected voltage between a first electrode and a second electrode, wherein the first and second electrodes are positioned along an electrode assembly of the ablation catheter, and wherein the first electrode is distal to the second electrode, obtaining a second detected voltage between the second electrode and a third electrode, the third electrode positioned proximal to the second electrode.

Ablation systems and methods of the present disclosure control lesion depth and width such that, for example, wide and shallow lesions can be formed in target tissue in an anatomic structure of a patient during a medical procedure. Such wide and shallow lesions can be useful for treating, for example, thin tissue such as atrial tissue in atria of the heart of the patient.

Provided is a multifunctional high-frequency electric knife, comprising processing portion, sheath portion, and operating portion. The processing portion is provided with an electrode and a clip component; the electrode is provided with a hollow tubular portion; the electrode can be pushed out or retracted relative to far end of the sheath portion; the clip component can be pushed out or retracted relative to far end of the sheath portion; the sheath portion is disposed at near end of the processing portion and comprises a hollow pull rod and a spring tube; and the operating part is located at near end of the sheath portion and comprises a high-frequency joint connected to the electrode by wire, a component driving, by operating line, the electrode to move, a member driving the hollow pull rod to move, and a liquid inlet allowing liquid to flow to the hollow tubular portion of the electrode.

The subject of this disclosure includes an apparatus for visually supporting a tissue ablation procedure, including a display comprising a user interface; and at least one processor in communication with the display, the at least one processor configured to control one or more of a plurality of electrodes of a radiofrequency balloon catheter to ablate organ tissues of one or more targeted pulmonary veins; determine a characteristic, based on ablation parameters of the radiofrequency balloon catheter, of pulmonary vein isolation (PVI) success rate; and present, on the display, visual information corresponding to each electrode for an indication, based on the characteristic, for PVI success rate.

Electrosurgical lysing devices and related systems and methods. In some embodiments, the lysing device may comprise a lysing tip comprising a plurality of beads. One or more of the plurality of beads may be electrically non-conductive, at least along their respective surfaces. The lysing tip may further comprise at least one lysing member defining at least one lysing segment extending between each pair of adjacent beads. At least a subset of the plurality of beads may protrude both distally and proximally relative to the at least one lysing member.