An interface joint with one or both of a needle actuation mechanism or an integrated shaft rotation mechanism. The interface joint comprises a flexible shaft between a housing and an electrosurgical instrument, e.g. for conveying power and/or fluid therebetween. The needle actuation mechanism comprises an actuation rod extending out of the housing and an actuator movably mounted on the housing. The shaft rotation mechanism comprises a rotation actuator rotatably mounted on the housing and operably coupled to the flexible shaft. Providing an integrated shaft rotation mechanism may obviate the need for a separate torque transmission unit. The improved needle actuation mechanism may use a pivoting connection to enable longer needle extension distances to be achieved for a given actuation distance.

A device is described for treating a nasal airway by modifying a property of a nasal tissue of or near a nasal valve of the airway, without using a surgical incision or an implant, to decrease airflow resistance or perceived airflow resistance in the nasal airway. Various embodiments include an elongate shaft, a bipolar radiofrequency delivery member extending from one end of the shaft, and a handle attached to the elongate shaft at an opposite end from the radiofrequency delivery member. The radiofrequency delivery member is sized to be inserted into a nose and configured to at least temporarily deform the nasal tissue and deliver radiofrequency energy. The radiofrequency delivery member includes two rows of protruding electrodes disposed on a tissue contact surface, and the device is configured to deliver radiofrequency energy from one row of electrodes to the other row of electrodes.

Techniques are disclosed, including methods and systems/apparatus, that can be used to treat cancerous tissue by exploiting the fact that such tissues have vascular branching with fractal descriptions and fractal dimensions, which are different from those found in normal soft tissue vascular branching. Such fractal branching of diseased tissue can produce resonances, or preferential energy absorption, when irradiated by either ultrasound and/or radio frequencies of EM energy; these resonances are not shared by the vascularization in normal soft tissue. Accordingly, one or more specific arrangements of multiband radiation (e.g., RF and/or ultrasonic) used to irradiate such diseased tissue will cause heating and possibly localized necropsy of tumor blood vessels, with little or minimal damage to surrounding healthy tissue. Embodiments can utilize ablation devices in conjunction with RF and/or ultrasonic sources. Embodiments can further utilize chemotherapy (before, during, or after hyperthermic treatment) for enhancing cancer treatment.

The present application relates to the technical field of pulse ablation, in particular to an electric pulse ablatograph for an endoscope, which includes: an electrode assembly including a central electrode and a cylindrical electrode and configured to pass through a working channel of the endoscope into a body and transmit a pulse to tissues in use; a pulse waveform generator coupled to the electrode assembly and configured to transmit pulse voltage to the electrode assembly; an electrode driving device configured to drive the central electrode and the cylindrical electrode; a parameter input device configured to configure coordinate information of an ablation region; and a control device in signal connection with the parameter input device and in control connection with the electrode driving device. The control device respectively controls the displacement of the central electrode and cylindrical electrode according to preset coordinate information through the electrode driving device; when a discharging end of the electrode assembly reaches a preset position, the control device controls the pulse waveform generator to be connected with the electrode assembly. A natural channel in a human body is used to deliver the electrode to a complex area of the human body for ablation, thus decreasing the trauma to the human body.

Ablation systems and methods detect and address distortion caused by a variety of factors. A method includes measuring a temperature curve at target tissue; applying ablation energy to the target tissue; determining a peak temperature on the temperature curve; if the peak temperature is greater than the predetermined peak temperature, determining a time at which the temperature curve crosses to a lower temperature; and if the determined time is greater than a predetermined time, generating a message indicating that the target tissue was successfully ablated. Another method includes determining a distance between a remote temperature probe and an ablation probe, applying ablation energy to target tissue, measuring temperature at the remote temperature probe, estimating ablation size based on the determined distance and the temperature measured by the remote temperature probe, and determining whether the target tissue is successfully ablated based on the estimated ablation size.

A system, ablation probe, and method is provided for treating tissue, e.g., tissue having tumors. The treatment system is configured to automatically deliver infusaid to tissue when needed and comprises an ablation probe having an ablative element and at least one perfusion exit port. The system further comprises an ablation source operably coupled to the ablative element, and a pump assembly operably coupled to the perfusion exit port(s). The pump assembly is configured for pumping infusaid out through the perfusion exit port(s), preferably during the ablation process. The system further comprises a feedback device configured for controlling the amount of infusaid displaced by the pump assembly based on a sensed tissue parameter, e.g., tissue temperature or tissue impedance.

An elongated medical tubular assembly is configured to improve, at least in part, transmission of a signal from the signal-transmitting device, received, at least in part, within the elongated medical tubular assembly, toward the signal-transceiving device of the medical-imaging system. The elongated medical tubular assembly defines a lumen extending from a distal tip toward a proximal end of the elongated medical tubular assembly; and the lumen is configured to receive, at least in part, the signal-transmitting device in such a way that the lumen, in use, receives, at least in part, the signal-transmitting device at the signal-liberating feature.

Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain. The modulation may be performed by a neuromodulation device (e.g., an energy delivery device).

Cystic lesions can be treated by electroporation. For example, this document describes methods and devices for endoscopic ultrasound-guided ablation of cystic lesions using a needle for electroporation.

Methods and apparatuses (e.g., devices, instruments and systems, including applicator handles for use with pulse generators) for automatically and/or mechanically setting impedance matching for connecting the applicator handle with different electrode tips. These methods and apparatuses may be useful for applying therapeutic energy, including but not limited to short, high field strength electric pulses, while avoiding the risk of arcing or otherwise harming the tissue.