The electrosurgical instrument includes an electrode and an insulator arrangement. The latter includes an instrument hose and an insulator arrangement arranged at its distal end. In the instrument hose a longitudinal thrust element is arranged for defining the position of the electrode relative to the distal end of the insulator arrangement. The instrument comprises a stop and a counter stop, whereby the counter stop is assigned to the electrode and/or the thrust element. An elastically deformable device is configured to pretension the counter stop in a distal direction against the stop in order to prevent a movement of the electrode in a proximal direction relative to the distal end of the insulator arrangement and/or the instrument hose during bending or curving of the instrument hose.

Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.

A mechanism for adding or updating a heat distribution model stored in a heat distribution model database. A heat distribution model is usable to determine a heat distribution about an ablation device when it is operated, and can be usable to derive thermal profiles in the vicinity of the ablation device. The mechanism comprises obtaining information about fixed properties of the ablation device, generating a heat distribution model based on the fixed properties, and modifying the heat distribution model if, when used, a generated thermal profile is inaccurate.

An intravascular catheter for peri-vascular nerve activity sensing or measurement includes multiple needles advanced through supported guide tubes (needle guiding elements) which expand with open ends around a central axis to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the perivascular space. The system also may include means to limit and/or adjust the depth of penetration of the needles. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. The addition of an injection lumen at the proximal end of the catheter and openings in the needles adds the functionality of ablative fluid injection into the perivascular space for an integrated nerve sending and ablation capability.

Systems, devices, and methods for transvascular ablation of target tissue are disclosed herein. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are method of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.

The invention provides systems, devices, and methods for the delivery, deployment, and positioning of magnetic compression devices at a desired site so as to improve the accuracy of anastomoses creation between tissues, organs, or the like.

A self-contained, battery powered transseptal crossing system is disclosed. An elongate, flexible electrically conductive needle body has a proximal end and a distal end. An insulation layer surrounds the sidewall and leaves exposed a distal electrode tip. A generator is configured to deliver RF energy to the electrode tip, and includes a processor configured to take impedance measurements at the tip to confirm contact with the intra atrial septum and/or confirm entry into the left atrium.

Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.

Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain. The modulation may be performed by a neuromodulation device (e.g., an energy delivery device).

An instrument guide (334) is attachable to an ultrasound imaging probe (304) to guide a needle. The instrument guide comprises a length (404), a width (406) and a height (408), a coupler (336) configured to couple the instrument guide to the ultrasound imaging probe, and a single elongate needle guide slot (410) configured to guide placement of the needle for an ultrasound-guided procedure. In another instance, the instrument guide is attached to the probe via a coupler (336). A method includes attaching a needle guide to an ultrasound imaging probe, wherein the needle guide includes a single elongate needle guide slot configured to guide placement of a needle during an ultrasound-guided needle placement procedure, positioning the probe relative to tissue of interest, and placing a needle at the tissue of interest using the needle guide.