A method for removing tissues may comprise disposing a tissue resection device at a target tissue site, causing the tissue resection device to resect a core of tissue from the target tissue site, removing the core of tissue from the body, wherein the removing the core of tissue from the body creates a core cavity at the target tissue site. A tracking apparatus may be configured to determine a position of a portion of the tissue resection device in three dimensional space.

A method for removing tissues may comprise disposing a tissue resection device at a target tissue site, causing the tissue resection device to resect a core of tissue from the target tissue site, removing the core of tissue from the body, wherein the removing the core of tissue from the body creates a core cavity at the target tissue site.

Retrieval of material from vessel lumens can be improved by use of a distal element comprising an expandable mesh. a treatment device includes an elongated member having a proximal portion and a distal portion configured to be positioned within a blood vessel at a treatment site at or near a thrombus. A distal element comprising an expandable mesh is coupled to the distal portion of the elongated member via a connection assembly. In an expanded state, at least a portion of the mesh is configured to be in apposition with the blood vessel wall at the treatment site to anchor or stabilize the elongated member with respect to the blood vessel. The distal element can be electrically coupled to an extracorporeal current generator.

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and/or other pulmonary diseases or disorders.

Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for interventionally treating a cancerous tumor and cancer related pain are disclosed.

Methods, apparatuses, and computer program products implement embodiments of the present invention that include grouping a set of electrodes disposed at a distal end of a medical probe and configured to contact tissue in a body cavity into a plurality of groups of adjacent electrodes. A set of selectable widgets having a one-to-one correspondence with the groups are presented on a display, and in response to receiving an input indicating selection of a given widget, an ablation selection status of one or more of the electrodes in the group corresponding to the selected widget can be toggled.

A surgical device integrating a suction mechanism with a coagulation mechanism is provided for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source. A fluid source to passively transport fluid along the contacted soft tissue surface may be provided in order to push the maximum temperature deeper into tissue.

The present invention relates to an ablation assembly (100) to treat target regions of a tissue (41) in organs (44) comprising: an ablation catheter (1) comprising an elongate shaft (13) having a longitudinal main direction (X-X), said elongate shaft (13) comprising at least a shaft distal portion (17), said shaft distal portion (17) comprising a shaft distal portion distal end (19);
said ablation catheter (1) comprising an inner lumen (118) arranged within the elongate shaft (13);
said ablation catheter (1) comprising a shaft ablation assembly (20) fixedly disposed at said shaft distal portion (17), the shaft ablation assembly (20) being configured to deliver both thermal energy for ablating said tissue (41) and non-thermal energy for treating said tissue (41); at least a shape setting mandrel (26) disposed within the ablation catheter (1), the shape setting mandrel (26) being insertable within the inner lumen (118) and removable from the inner lumen (118),
wherein the shape setting mandrel (26) is free to move in respect of the inner lumen (118) avoiding any constraint with said shaft distal portion (17) during the shape setting mandrel insertion,
wherein the shape setting mandrel (26) comprises at least a pre-shaped configuration and the shape setting mandrel (26) is reversibly deformable between at least a straight loaded configuration and said pre-shaped configuration,
wherein, when the shape setting mandrel (26) is fully inserted in the shaft distal portion (17), the shape setting mandrel (26) is configured to shape set said shaft distal portion (17) with said pre-shaped configuration.

The purpose of this invention is to provide pulsed field ablation (PFA)-based systems and devices for treating arrhythmia, which includes a pulsed voltage console, a pacing and ECG unit, and an ablation catheter. The pulsed voltage console is comprised of an electric pulse generator, a controller, a user interface(UI), and a converter. The pacing and ECG unit is comprised of an ECG recorder, a pacing catheter, a cardiac stimulator, and a mapping catheter. The pacing electric signal is transmitted to the pulsed voltage console. Voltage pulse delivery is synchronized to join pacing signal. Based on the pacing signal, a voltage pulse waveform is delivered during the refractory period of the cardiac cycle. The ablation catheter is connected to the system console through a converter, transferring the electric field energy to the tissue through electrodes on the ablation catheter. The ablation catheter includes a spline basket. The distal end of the spline basket is coupled with an annular catheter that can go into pulmonary vein (PV). Irreversible electroporation can be formed locally, linearly, or circularly, and evenly distributed over a large area, achieving the purpose of effectively treating atrial flutter, supraventricular tachycardia, atrial fibrillation, and other arrhythmias.

The instrument according to the invention for electrosurgically impacting biological tissue comprises an electrode (18) as well as a light guide (21), which is connected to a light inlet window (19), which is formed by means of a fluid body (27). The light guide is connected to a light analysis device (13), so as to absorb the light, which is generated at the electrode (18) in response to the HF surgery and so as to supply it to the light analysis device (13). The light inlet window (19) is arranged at the point of origin of the light, namely immediately at the electrode, that is, at the spark, which is generated. An adulteration of the absorbed light by means of smoke or particle deposition on the light inlet window (19) can virtually be avoided.