A surgical laser system includes a pump module configured to produce pump energy within an operating wavelength, a gain medium configured to convert the pump energy into first laser energy, a non-linear crystal (NLC) configured to convert a portion of the first laser energy into second laser energy, which is a harmonic of the first laser energy, an output, and a first path diversion assembly having first and second operating modes. When the first path diversion assembly is in the first operating mode, the first laser energy is directed along the output path to the output, and the second laser energy is diverted from the output path and the output. When the first path diversion assembly is in the second operating mode, the second laser energy is directed along the output path to the output, and the first laser energy is diverted from the output path and the output.

A system for creating micro-channels through superficial corneal epithelium, the system including: a femtosecond laser having a pulse energy range of 1 to 20 microjoules (μJ) and a capability of generating a laser beam having a wavelength of 700-1100 nanometers (nm) and a repetition rate of 1 kilohertz to 1 megahertz, a laser delivery system comprising a beam expander, a scanning lens having a numerical aperture (NA) of 0.05 to 0.5 and a focusing objective, and control software that controls the delivery system such that the laser beam is scanned in a pattern. The system is used to noninvasively increase corneal epithelial permeability to therapeutic agents through micron-scale channels created through the corneal epithelium by the system or to induce wound healing in a cornea in a subject following creation of micron-scale channels in the cornea.

Exemplary embodiments of the present disclosure apparatus and methods that provide for subtractive material processing, including efficient and precise ablation of tissues. Certain embodiments include a first laser configured to direct a first pulse of energy at a first wavelength to a region of tissue; a second laser configured to direct a second pulse of energy at a second wavelength to the region of tissue; and a control system configured to control operation of the first laser and the second laser.

A pulse application method includes: setting a wavelength of light within a range in which a temperature rise width of collagen fibers in living tissue when the light is applied to the living tissue is larger than a temperature rise width of water containing cells that are contained in the living tissue and that are present around the collagen fibers; and applying a pulse of light with the set wavelength to the living tissue to heat the living tissue.

Systems and methods for treating a body region are provided herein. A treatment device for treating a body region is provided, and may include a first applicator and a second applicator. The first and second applicators are held on the body region by a belt. The first applicator may include a first magnetic field generating device and a radiofrequency electrode. The second applicator may include a second magnetic field generating device. The first and second magnetic field generating devices may each generate a time-vary magnetic field with a plurality of sequential magnetic impulses to cause muscle contraction in the body region. The radiofrequency electrode may provide radiofrequency waves causing heating of tissue within the body region. The treatment device may further include an energy storage device and a switching device. The switching device my discharge energy from the energy storage device to the first or the second magnetic field generating device to generate the time-vary magnetic field.

A pulsed laser skin treatment device is for laser induced optical breakdown of hair or skin tissue. A beam scanning system scans the beam to define a circular or arc path, using a rotated prism which implements a lateral shift to the beam. A focusing system at the output side of the beam scanning system focuses the incident light beam into a focal spot in the hair or skin tissue, and it rotates with the prism.

A trans-oral surgery device has a scaffold insertable into the vicinity of the larynx or hypopharynx of a subject. A support is arranged for holding a flexible optical fiber for delivering light to the subject. A plurality of tendons is connected to the support, and slidably anchors the support to the scaffold. The tendons are adjustable to move the support relative to the scaffold. The scaffold is provided at the front end of a blade, and the blade is non-straight.

A photoacoustic probe head (200a, 200b) is disclosed. The probe head (200a, 200b) comprises: a Fabry Perot acoustic sensor (202), an interrogation interface (A), an excitation input (B) and a two-axis mirror (204). The Fabry Perot acoustic sensor (200a, 200b) is operable to reflect an optical interrogation beam to create a reflected interrogation beam and to modulate the reflected interrogation beam in response to an acoustic signal at the acoustic sensor (202). The interrogation interface (A) is configured to receive an interrogation beam, and to receive the reflected interrogation beam from the acoustic sensor (202). The excitation input (B) is configured to receive an excitation beam for generating an acoustic field in a sample adjacent to the acoustic sensor (202). The two axis mirror (240) is configured to scan the interrogation beam between different locations of the acoustic sensor (202).

A method and laser surgical devices for surgical incising and ablating living tissues using laser beam and effecting enhanced surgical haemostasis concurrently with incising and ablating are disclosed. The method requires a surgical laser beam that is pulsed and is highly absorbed in living tissues and enhanced haemostatic action is achieved using along with the surgical laser beam energy, delivered in pulses, another separately controlled energy effecting haemostasis, by applying the second energy in any and every given spot of incising and ablating in a preemptive and focused manner, which minimizes haemostasis-related damage to surrounding tissues. In one embodiment a heated gas jet from a hollow core optical fiber transmitting the surgical laser beam is used. In other embodiments an ancillary laser radiation at a wavelength chosen specifically to minimize haemostasis-related damage to tissue is utilized for preemptive and controlled haemostatic effect.

The present disclosure provides systems, devices, and methods for penetrating a biological membrane. The system may comprise a laser unit configured to generate one or more laser beams. The system may comprise a set of targeting optics configured to direct the one or more laser beams to a target region of the biological membrane. The system may comprise a raster scanner operatively coupled to the laser unit and the set of targeting optics. The system may comprise a non-transitory computer readable storage medium comprising a set of instructions. The set of instructions may be configured to control at least one of the laser unit, the set of targeting optics, or the raster scanner to photodisrupt the target region of the biological membrane to a target depth while minimizing damage to one or more blood vessels in proximity to the target region.