Certain aspects of the present disclosure provide a thermally robust laser probe assembly comprising a cannula, wherein one or more optical fibers extend at least partially through the cannula for transmitting laser light from a laser source to a target location. The probe assembly further comprises a lens housed in the cannula and a protective component press-fitted to the distal end of the cannula, wherein the lens is positioned between the one or more optical fibers and the protective component.

A laser atherectomy device includes a light delivery catheter equipped with sensors for monitoring physical characteristics at a laser application site. An integrated control unit utilizing data from said sensors is provided to optimally adjust laser energy parameters and to provide for safe and efficacious ablation of the blood vessel occlusion.

A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108) or a heart valve includes an inflatable balloon (104), an optical fiber (122), and an energy source (124). The optical fiber (122) has a fiber proximal end (122P), and a fiber distal end (122D) positioned within the inflatable balloon (104). The optical fiber (122) is configured to receive an energy pulse so that the optical fiber (122) emits light energy in a direction away from the optical fiber (122) to generate a plasma pulse within the inflatable balloon (104). The optical fiber (122) can be tapered from the fiber proximal end (122P) toward the fiber distal end (122D). The energy source (124) in optical communication with the fiber proximal end (122P) of the optical fiber (122), and can include a laser. The optical fiber (122) includes a first fiber member (250) and a second fiber member (258) that is coupled to the first fiber member (250). The first fiber member (250) can be fused to the second fiber member (258) in a fused region (256). The first fiber member (250) and the second fiber member (258) can be formed as a unitary structure. The catheter system (100) can also include a ferrule (248) that encircles the fused region (256).

A method for treating a treatment site (106) within or adjacent to a vessel wall (108) or heart valve includes tapering an optical fiber (122) from a fiber proximal end (122P) to a fiber distal end (122D); positioning the optical fiber (122) such that the fiber distal end (122D) is positioned within an inflatable balloon (104); coupling an energy source (124) in optical communication with the fiber proximal end (122P); and receiving an energy pulse from the energy source (124) into the fiber proximal end (122P) so that the optical fiber (122) emits light energy in a direction away from the optical fiber (122) to generate a plasma pulse within the inflatable balloon (104). The method can further include coupling a first fiber member (250) to a second fiber member (258), which can include fusing the first fiber member (250) to the second fiber member (258) at a fused region (256); and encircling the fused region (256) with a ferrule (248).

A surgical device may include a housing configured for handling by a user and comprising a plurality of operator interfacing features. The device may also include a patient interfacing tip arranged at, or spaced apart from, a distal end of the housing and controllable by the operator interfacing features. The patient interfacing tip may include a pair of jaws configured to grasp tissue, an electrode on each jaw configured to seal tissue, and an articulating blade configured to cut tissue in a grasp of the pair of jaws. The device may also include an optical element extending from the housing to the patient interfacing tip and configured to emit laser energy to cut tissue, wherein the pair of jaws, electrode, and articulating blade are adapted for coarse cutting of tissue and the optical element is configured for precise cutting of tissue.

A catheter system for treating a treatment site within or adjacent to the heart valve within a body of a patient includes an energy source, an energy guide and an energy director. The energy source generates energy. The energy guide includes a guide proximal end and a guide distal end. The energy guide is configured to receive energy from the energy source and guide the energy from the guide proximal end toward the guide distal end. The energy director includes a director wall that defines a director interior, and a director distal end that is selectively positioned substantially adjacent to the treatment site. The guide distal end of the energy guide is positioned within the director interior. The director distal end is at least partially open toward the treatment site.

A surgical laser system includes an array of laser diodes that are configured to output laser energy, a fiber bundle, a delivery fiber, and a tubular sheath. The fiber bundle includes a plurality of optical fibers and has a proximal end that is configured to receive laser energy from the array of laser diodes. The delivery fiber includes a proximal end that is configured to receive laser energy from a distal end of the fiber bundle. The tubular sheath defines a lumen, in which at least a portion of the delivery fiber is disposed. The tubular sheath is insertable into a working channel of an endoscope or a cystoscope. A distal end of the tubular sheath is configured to deliver laser energy discharged from the delivery fiber into a body of a patient.

A system and method for determining or estimating the presence and effect of light-attenuating inhomogeneities in tissue when performing medical treatment or diagnostics using optical members in tissue. The system and method comprising inserting a plurality of optical members into the tissue, and then measuring by emitting light through a sub-set of optical members at a time, while measuring the light collected by another sub-set of optical members. Combining said measurement data with a model for light propagation in tissue, and setting up a system of equations. Solving the unknown attenuation values from said system of equations.

Described herein are systems with interleaved light sources and methods of their use. In some embodiments, a system includes a plurality of light sources, each of which has a bright phase and a dark phase, the system being arranged and constructed so that, for a first light source and a second light source of the plurality, the bright phase of the first light source occurs during the dark phase of a second light source. The example method may further include providing light from the second light source during a dark phase of the first light source. A first and/or second light source may be a swept source or a broadband source. A first and/or second light source may be a laser.

Disclosed herein is a medical device. The medical device includes a sheath, a laser fiber, a basket section, and a laser beam splitter. The laser fiber is configured to extend from an end of the sheath. The basket section includes flexible members. At least a portion of the flexible members are between the sheath and the laser fiber. The laser beam splitter is coupled to the laser fiber.