The endoluminal prosthesis assembly comprises a first stent graft having a first end and a second end and an interior lumen. The first stent graft has an expanded position and a compressed position and defines an access port disposed through a wall of the first stent graft between the first and second ends of the first stent graft. The endoluminal prosthesis assembly further comprises a second stent graft being disposed entirely within the interior lumen of the first stent graft. The second stent graft is disposed within the first stent graft and has an expanded position and a compressed position. In the compressed position, the second stent graft contacts only a portion of an interior wall of the first stent graft and the access port is in fluid communication with the interior lumen of the first stent graft.

The present application discloses a stent-graft prosthesis and a method for navigating such stent-graft prosthesis e.g. to a branch vessel. A first stent-graft prosthesis may include a main body and at least one lateral side branch connected to the main body. A further stent-graft prosthesis according to examples has a body having a generally tubular wall structure, the wall structure of the further stent-graft prosthesis including an orifice element (610) for receiving a guiding element (10). Preferably the wall structure has an overlap region (630) for interconnection, e.g. to the first stent-graft prosthesis. The orifice element (610) is then arranged at said overlap region, wherein said overlap region is preferably arranged at a proximal end region of said body. The guiding element (10) preferably is a textile thread or suture thread, optionally with a radiopaque marker, such as a fiducial marker and/or a radiopaque elongate marker extending at least along a portion of a length of said guiding element (10).

A covered stent (100A), including a mesh-shaped support structure, and further including a first section (10A) and a second section (20A) connected to a proximal end and/or a distal end of the first section. The first section includes a plurality of first corrugated rings (11A), and a first covering film (12A) which covers surfaces of the first corrugated rings; the second section includes a plurality of second corrugated rings (21A), two adjacent second corrugated rings being fixedly connected to each other; a plurality of windows (201A) are formed between the plurality of second corrugated rings; and the plurality of first corrugated rings and the plurality of second corrugated rings form the support structure. The second section of the covered stent will not block an opening of a branch vessel (400), and thus it is not necessary to reduce the length of the covered stent in a main branch vessel, such that the covered stent has a sufficiently long anchoring area in the main branch vessel so as to ensure that the covered stent has sufficient anchoring force and thus prevent the displacement or endoleak of a distal end of the covered stent, thereby ensuring a good occluding effect.

Systems and methods of adjusting the diameter of an endoluminal prosthesis that allows for controlled radial deployment of the endoluminal prosthesis and the ability to revise the positioning of the endoluminal prosthesis after unsheathing. The endoluminal prosthesis includes a stent graft having a tubular graft wall, a stent, a main strand, a proximal strand, and a distal strand.

A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes a frame and the seal is formed from a plurality of outwardly extending fibers.

A joining arrangement between a main tube and a side arm (5) in a side arm stent graft (1). The side arm (5) is stitched into an aperture (11) in the main tube and is in fluid communication with it. The aperture is triangular, elliptical or rectangular and the side arm is cut off at an angle to leave an end portion having a circumferential length equal to the circumference of the aperture. The side arm can also include a connection socket (76) comprising a first resilient ring (79) around the arm at its end, a second resilient ring (80) spaced apart along the arm from the first ring and a zig zag resilient stent (82) between the first and second rings. The zig-zag resilient stent can be a compression stent. Both the main tube and the side arm are formed from seamless tubular biocompatible graft material.

A method for determining a pressure gradient between proximal and distal locations within a vasculature of a patient. The method includes deploying an ancillary device within the vasculature. The ancillary device integrates a proximal sensor at the proximal location and a distal sensor at the distal location. The method further includes deploying, via a stent graft delivery system, a stent graft within the vasculature to obtain a deployed stent graft. The ancillary device is independent from the stent graft delivery system and the stent graft. The method further includes outputting proximal pressure data from the proximal sensor and indicative of pressure at the proximal location and distal pressure data from the distal sensor and indicative of pressure at the distal location. The method also includes determining the pressure gradient using the proximal and distal pressure data.

A catheter system for treating lesions is provided. The system is suitable for treatment of bifurcation lesions, has a low profile and provides substantially predictable translational and rotational positioning. In one embodiment, the system includes a fixed wire balloon catheter and a partially attached guidewire lumen, wherein the guidewire lumen is attached to the catheter at a crotch point. The location of the crotch point is predetermined so as to provide substantially predictable positioning. Several embodiments of the system are described for various types of lesions and vessel configurations.

Examples of prostheses are provided having an internal branch. A tubular graft body of the prosthesis defines a main lumen extending between an inflow end and an outflow end of the graft body. A stent structure is coupled along the graft body. A trough is at least partially defined by a trough wall extending into the main lumen from a sidewall of the graft body. A side branch defines a branch lumen and extends from the trough within the main lumen towards one of the inflow or outflow ends of the graft body. A branch lumen facing surface of the trough wall is a continuous surface with an outer surface of the sidewall of the graft body. A boundary of the trough may be configured to provide a smooth transition surface between the trough and the sidewall.

Embodiments discussed herein are directed to devices, systems and methods for effectively treating post endovascular procedure complications such as endoleaks within an aneurysm sac. Some embodiments may include a delivery system with an integral aneurysm sac conduit configured for the introduction of materials which may be useful for treating endoleaks or the like.