A stent graft system includes a first layer of graft material, a second layer of graft material, one or more stent members, one or more reducing belts, and a release wire. The one or more stent members are located between the first layer of graft material and the second layer of graft material. The second layer of graft material is formed to have a corresponding channel over each of the one or more stent members. The one or more reducing belts each include a loop at both ends and each is located in a corresponding channel around a corresponding one of the stent members. The release wire passes through both loops of each of the one or more reducing belts when the one or more stent members are in a compressed state. Pulling the release wire allows for the stent graft system to radially expand.

A stent or other prosthesis may be formed by coating a single continuous wire scaffold with a polymer coating. The polymer coating may consist of layers of electrospun polytetrafluoroethylene (PTFE). Electrospun PTFE of certain porosities may permit endothelial cell growth within the prosthesis.

Stents that are adapted to be balloon-expanded and include a plurality of rings of repeating cells, wherein adjacent rings are connected by s-shaped or omega-shaped crosslink connectors or a combination of both connectors. The configurations, materials, and/or dimensions of these devices, including the unit cells and/or crosslink connectors allow the stents to be expanded to a greater extent (e.g., up to or greater than 12 mm of diameter), and optionally with reduced foreshortening and without increasing the strain on the materials forming the crosslink connectors and unit cells. The biphasic arrangement of trapezoidal unit cells, as well as the configuration and arrangement of the s-shaped connectors, may allow these stents to expand while maintaining their radial compression strength and longitudinal compression strength with minimal recoil and stent foreshortening.

A small diameter vascular prosthesis includes an outer textile graft, an intermediate self-supporting coil or stent and an inner microporous layer. The outer textile graft allows for tissue ingrowth. The inner microporous layer provides blood impermeability without preclotting the prosthesis. The coil or stent provides kink resistance and resistance again collapsing of the outer textile graft and the inner microporous layer.

Methods, devices, and kits for implanting a vascular graft to perform hemodialysis treatments on patients with renal failure are disclosed. The kits can include access devices comprised of an access catheter having a guidewire lumen and stylet lumen, a guide tube having a curved distal end, a stylet, an actuator handle and a vascular graft. The methods describe techniques for using the described kits and devices for performing vascular procedures, such as percutaneous implantation of the vascular graft.

A medical appliance or prosthesis may comprise one or more layers of rotational spun nanofibers, including rotational spun polymers. The rotational spun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Rotational spun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis. Additionally, one or more cuffs may be configured to allow tissue ingrowth to anchor the prosthesis.

Bifurcated endoprosthetic devices, systems and methods are disclosed herein for treating disease of human vasculature. In various embodiments, a bifurcated endoprosthesis includes a trunk portion and a plurality of legs, where the legs are constrained such that they maintain alignment with one another. In some examples, the legs and bifurcation of an endoprosthetic device may be formed by cutting a tubular graft component along a portion of less than its entire circumference in a longitudinally central region, and then folding the tubular graft component along the uncut portion to define two legs, where the uncut portion defines the bifurcation. In some such examples, the folded tubular graft component can be coupled with a tubular trunk component to form the bifurcated endoprosthetic device.

Bifurcated endovascular prostheses used to treat diseased blood vessels, such as arteries, are disclosed. In some embodiments, the bifurcated endovascular prosthesis is configured to be implanted within the diseased blood vessels adjacent a diseased section. The bifurcated endovascular prosthesis includes a primary stent graft and a secondary stent graft. The primary stent graft includes a pocket or sleeve disposed within a bore. A proximal portion of the secondary stent graft is disposed within the pocket or sleeve. Blood flow through the bifurcated endovascular prosthesis is divided into two flows, a first flow through the primary stent graft and a second flow through the secondary stent graft.

The invention relates to an artificial vascular graft comprising a primary scaffold structure encompassing an inner space of the artificial vascular graft, said primary scaffold structure having an inner surface facing towards said inner space and an outer surface facing away from said inner space, a coating on said inner surface, wherein a plurality of grooves is comprised in said coating of said inner surface. The primary scaffold structure comprises further a coating on said outer surface. The primary scaffold structure and the coating on said inner surface and on said outer surface are d designed in such a way that cells, in particular progenitor cells, can migrate from the periphery of said artificial vascular graft through said outer surface of said coating, said primary scaffold structure and said inner surface to said inner space, if the artificial vascular graft is used as intended. The invention relates further to a method for providing said graft.

The disclosure relates to a medical system for treating stenosis in intracranial blood vessels including a compressible and self-expandable implant for covering the stenosis, said implant having a lattice structure, at least some sections of which are provided with a cover made of an electrospun fabric, wherein the fabric has irregularly sized pores, and a balloon catheter for dilating the stenosis and/or introducing the implant into the blood vessel.