A stent-graft prosthesis includes a generally tubular outer PTFE layer, a generally tubular helical stent, a generally tubular inner PTFE layer, and a suture or fabric support strip. The outer PTFE layer defines an outer layer lumen. The helical stent is disposed within the outer layer lumen and defines a stent lumen. The inner PTFE layer is disposed within the stent lumen and defines an inner layer lumen. The suture includes a suture first end coupled to a stent first end and a suture second end coupled to a stent second end, with the suture disposed between the outer PTFE layer and the inner PTFE layer. Alternatively, the fabric support strip is disposed between the outer and inner PTFE layers. The suture or fabric support strip may include a plurality of sutures or fabric support strips and may be spaced equally around a circumference of the inner PTFE layer.

This invention is a system for the treatment of body passageways; in particular, vessels with vascular disease. The system includes an endovascular graft with a low-profile delivery configuration and a deployed configuration in which it conforms to the morphology of the vessel or body passageway to be treated as well as various connector members and stents. The graft is made from an inflatable graft body section and may be bifurcated. One or more inflatable cuffs may be disposed at either end of the graft body section. At least one inflatable channel is disposed between and in fluid communication with the inflatable cuffs.

A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.

A medical appliance or prosthesis may comprise one or more layers of rotational spun nanofibers, including rotational spun polymers. The rotational spun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Rotational spun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis. Additionally, one or more cuffs may be configured to allow tissue ingrowth to anchor the prosthesis.

An aortic stent-graft includes a main aortic stent-graft and a plurality of branch arterial stent-grafts. The main aortic stent-graft includes a proximal segment, a depressed segment, and a distal segment; steps are provided on a top surface of the depressed segment from left to right; one or two first orifices are formed on a middle-upper part of a right side wall of the proximal segment, and one or two second orifices are formed on a right side wall of the steps; a first inner chimney stent is fixed inside the first orifice and a second inner chimney stent is fixed inside the second orifice; the first inner chimney stent is sutured along an inner wall of the proximal segment, and the second inner chimney stent is sutured along an inner wall of the steps; and one of the branch arterial stent-grafts is placed inside each inner chimney stent.

An endoluminal prosthesis system for a branched body lumen comprises a branch vessel prosthesis. The branch vessel prosthesis is deployable within a branch vessel body lumen and comprises a stent having a generally tubular body portion, a flareable proximal end portion, and a coupling portion disposed intermediate the body portion and the flareable portion. The coupling portion is more crush-resistant than the body portion. The flareable proximal end may be disposed within a fenestrated stent graft with coupling portion disposed in the fenestration of the fenestrated stent graft.

A device includes a first end portion, a second end portion, an intermediate portion between the first end portion and the second end portion, and a graft material coupled to at least the intermediate portion. The first end portion has a first end diameter. The second end portion has a second end diameter larger than the first end diameter. The intermediate portion tapers between the first end portion and the second end portion. A method of diverting fluid flow from a first passage to a second passage comprising deploying the device in a third passage between the first passage and the second passage, expanding the first end portion against sidewalls of the first passage, and expanding the second end portion against sidewalls of the second passage.

A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration engages the personalized prosthesis with the treatment site. The mesh or membrane is personalized to match the treatment site in the expanded configuration, and has an outer surface that substantially matches the treatment site shape and size. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed.

An implant device may include a body of a first material and defining a lumen and at least two arcuate rings of a second material embedded within the body. In one embodiment, the second material does not connect a first ring of the at least two arcuate rings to an adjacent second ring of the at least two arcuate rings.