Described herein are intraocular lenses and methods of implantation. In one aspect, the lens includes a shape changing optical element; a force translation element having a first end region coupled to the optical element and a second end region extending towards a ciliary structure, and an attachment portion coupled to the second end region of the force translation element and configured to contact the ciliary structure. The force translation element is configured to functionally transmit movements of the ciliary structure into a force exerted upon the optical element to effect an accommodating and a disaccommodating change of the optical element.

Accommodating intraocular lens including a combination of variable lenses. Firstly, a variable lens including two spherical lenses fitted onto two optical elements to provide variable optical power of which the degree depends on the degree of movement of at least one of spherical lens along the optical axis. Secondly, a variable lens comprising at least two cubic surfaces fitted onto the same two optical elements which provides a lens of variable optical power of which the degree depends on the degree of movement of at least one of the optical elements in a direction perpendicular to the optical axis. The combination of variable lenses is fitted into a mechanical construction providing said movements of the optical elements.

The present disclosure provides a three-lens IOL system including a first, anterior lens, a second, posterior lens rigidly connected to the first lens by at least one rigid member such that the second lens is a fixed distance from the first lens along an axis, a third, center, moveable lens positioned between the first lens and the second lens and adapted to move linearly along the axis anteriorly in a direction of the first lens or posteriorly in a direction of the second lens to change an optical power of the system, and an articulating actuator that contacts the moveable lens and a capsular bag of an eye when the IOL system is implanted in the capsular bag, the articulating actuator adapted to move the moveable lens linearly along the axis.

An intraocular optic assembly can include a plurality of stanchions and at least one optic. Each of the stanchions can extend between a respective base and distal ends. The base ends can be disposed in spaced relation to one another about a first arcuate periphery. The distal ends can be disposed in spaced relation to one another about a second arcuate periphery. The first arcuate periphery can have a greater radius than the second arcuate periphery. The at least one optic can have a central optic axis, an anterior side, a posterior side, and a center disposed between the anterior side and the posterior side through which the central optic axis extends. The at least one optic can be connected with each of the plurality of distal ends whereby the center of the optic is moved along the central optic axis in response to contraction of the first arcuate periphery.

An intraocular lens (IOL) for implantation within a capsular bag of a patient's eye comprises an optical structure and a haptic structure. The optical structure comprises a planar member, a plano convex member, and a fluid optical element defined between the planar member and the plano convex member. The fluid optical element has an optical power. The haptic structure couples the planar member and the plano convex member together at a peripheral portion of the optical structure. The haptic structure comprises a fluid reservoir in fluid communication with the fluid optical element and a peripheral structure for interfacing to the lens capsule. Shape changes of the lens capsule cause one or more of volume or shape changes to the fluid optical element in correspondence to deformations in the planar member to modify the optical power of the fluid optical element.

An intraocular lens (IOL) for implantation within a capsular bag of a patient's eye comprises an optical structure and a haptic structure. The optical structure comprises a planar member, a plano convex member, and a fluid optical element defined between the planar member and the plano convex member. The fluid optical element has an optical power. The haptic structure couples the planar member and the plano convex member together at a peripheral portion of the optical structure. The haptic structure comprises a fluid reservoir in fluid communication with the fluid optical element and a peripheral structure for interfacing to the lens capsule. Shape changes of the lens capsule cause one or more of volume or shape changes to the fluid optical element in correspondence to deformations in the planar member to modify the optical power of the fluid optical element.

An intraocular lens adapted to be implanted inside a capsular bag, comprising a peripheral portion comprising an anterior annular portion adapted to engage an anterior capsule portion, the anterior annular portion defining an anterior opening through which an optical axis passes, a posterior annular portion adapted to engage a posterior capsule portion, the anterior and posterior annular portions being adapted to keep the capsular bag open after implantation, and an optic portion disposed within the anterior opening and secured to and radially inward relative to the peripheral portion.

Accommodating intraocular lenses including an optic having an anterior element and a posterior element defining an optic fluid chamber, wherein the optic is aspheric across all powers throughout accommodation or disaccommodation. Intraocular lenses, optionally accommodating, where an optic portion is centered with a midline of a height of the peripheral portion, the height measured in the anterior to posterior direction.

The present disclosure provides intraocular artificial lenses having a variable optical strength and methods of treating an eye disorder, such as presbyopia, using same. In some embodiments, the intraocular artificial lens comprises two optical elements that are moveable along the optical axis in relation to each other, for example in response to the accommodative process of the eye.

Ophthalmic implants such as sulcus implants which can include one or more drug delivery devices. Further provided herein are methods of using the drug delivery ophthalmic devices described herein for implantation into a subject's eye, e.g., into an eye's ciliary sulcus or capsular bag.