A medical appliance or prosthesis may comprise one or more layers of electrospun nanofibers, including electrospun polymers. The electrospun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Electrospun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis.

The invention relates to a method and a device for producing an implant, wherein a natural bone microstructure of a natural bone region is detected (S1), an implant region in the natural bone region is marked (S2), the detected bone microstructure in the marked implant region is analysed to determine reproduction parameters (S3), and on the basis of the determined reproduction parameters, an artificial microstructure for producing the implant is created (S4).

A hemi-arthroplasty bone joint implant has a first part (120) with a stem (111) tor intramedullary implanting into a metacarpal, mid a second part (110) to engage the trapezium is a translational manner, a hemi-arthroplasty articulating coupling (121). This allows multi-axial motion with translational movement of the second part over the trapezium and rotation of the first part (110) about the articulating coupling (121, 103). There is also a converter to convert the implant to a total arthroplasty implant in situ during revision surgery. The second part (110) and the hemi-arthroplasty coupling (100, 123, 121) are removable in situ during revision surgery. The first part (120) has an engagement threaded socket (117) for, after removal of the second part and the hemi-arthroplasty coupling, engaging the replacement coupling (200) and allowing mutual articulation of the first (120) and replacement parts (220). This forms a total arthroplasty joint implant.

Thin-film mesh for medical devices, including stent and scaffold devices, and related methods are provided. Micropatterned thin-film mesh, such as thin-film Nitinol (TFN) mesh, may be fabricated via sputter deposition on a micropatterned wafer. The thin-film mesh may include slits to be expanded into pores, and the expanded thin-film mesh used as a cover for a stent device. The stent device may include two stent modules that may be implanted at a bifurcated aneurysm such that one module passes through a medial surface of the other module. The thin-film mesh may include pores with complex, fractal, or fractal-like shapes. The thin-film mesh may be used as a scaffold for a scaffold device. The thin-film scaffold may be placed in a solution including structural protein such as fibrin, seeded with cells, and placed in the body to replace or repair tissue.

A hemi-arthroplasty bone joint implant has a first part (120) with a stem (111) tor intramedullary implanting into a metacarpal, and a second part (110) to engage the trapezium is a translational manner, a hemi-arthroplasty articulating coupling (121). This allows multi-axial motion with translational movement of the second part over the trapezium and rotation of the first part (110) about the articulating coupling (121, 103). There is also a converter to convert the implant to a toral arthroplasty implant in situ during revision surgery. The second part (110) and the hemi-arthroplasty coupling (100, 123, 121) are removable in situ during revision surgery. The first part (120) has an engagement threaded socket (117) for, after removal of the second part and the hemi-arthroplasty coupling, engaging the replacement coupling (200) and allowing mutual articulation of the first (120) and replacement parts (220). This forms a total arthroplasty joint implant.

A bioactive filamentary structure includes a sheath coated with a mixture of synthetic bone graft particles and a polymer solution forming a scaffold structure. In forming such a structure, synthetic bone graft particles and a polymer solution are applied around a filamentary structure. A polymer is precipitated from the polymer solution such that the synthetic bone graft particles and the polymer coat the filamentary structure and the polymer is adhered to the synthetic bone graft particles to retain the graft particles.

A tibial implant includes one or more stiffness-modifying features to reduce the stiffness of one or more sections of the tibial implant. The stiffness-modifying features may include slots, recesses, or passageways defined in various locations of the tibial implant to selectively reduce the stiffness of a tibial insert and/or tibial base of the tibial implant.

A modular spacer device for a knee joint includes a tibial element adapted to be constrained to an end of the tibial bone and a femoral element adapted to be constrained to an end of the femoral bone and to be articulated on the tibial element. The tibial element has first and second surfaces opposite to each other, and the femoral element has first surface and second surfaces opposite to each other. The first surface of the femoral element is convex and laterally has a curved, ammonite-shaped contour with a curvature radius that increases starting from a rear section with a curvature radius R1, a first central section having a curvature radius R2, a second central section having a curvature radius R3, and a front section having a curvature radius R4, with R1≤R2≤R3≤R4.

A zirconia material manufacturing method includes: dispersing hydroxyapatite powder in water to prepare a slurry having a hydroxyapatite powder concentration of 1%; and dipping zirconia in the slurry to form, on the zirconia, a coating layer containing hydroxyapatite.

A bone implant includes at least one bone-engaging surface designed to mate with an implant-engaging surface of a bone. In the preferred embodiment, the bone-engaging surface of the implant includes a wave pattern comprising at least one peak extending in a proximal direction or at least one valley extending in a distal direction. The implant-engaging surface of the bone also includes a matching wave pattern having at least one peak and valley. Upon mating the engaging surfaces, a bone-implant interface may be created wherein the peaks and valleys of the wave patterns are aligned. As a result, there is good surface contact area at the bone-implant interface which helps prevent loosening or rotating of the implant.