Intervertebral devices and systems, and methods of their use, are disclosed having configurations suitable for placement between two adjacent vertebrae, replacing the functionality of the disc therebetween. Intervertebral devices and systems contemplated herein are implantable devices intended for replacement of a vertebral disc, which may have deteriorated due to disease for example. The intervertebral devices and systems are configured to allow for ample placement of therapeutic agents therein, including bone growth enhancement material, which may lead to better fusion between adjacent vertebral bones. The intervertebral devices and systems are configured for use in minimally invasive procedures, if desired.

An implant is provided that is operable to be disposed between and fuse two sections of a bone. The implant includes a material that is operable to abut against the two sections of the bone. The material is porous and/or fibrous and is operable to receive at least one cellular growth factor.

An implant for therapeutically separating bones of a joint has two endplates each having an opening through the endplate, and at least one ramped surface on a side opposite a bone engaging side. A frame is slideably connected to the endplates to enable the endplates to move relative to each other at an angle with respect to the longitudinal axis of the implant, in sliding connection with the frame. An actuator screw is rotatably connected to the frame. A carriage forms an open area aligned with the openings in the endplates. The openings in the endplates pass through the carriage to form an unimpeded passage from bone to bone of the joint. The carriage has ramps which mate with the ramped surfaces of the endplates, wherein when the carriage is moved by rotation of the actuator screw, the endplates move closer or farther apart.

The invention relates to an implant (1) for introducing into a patient, having an implant body that is at least partially resorbable and is porous at least in some regions and that is made of a ceramic carrier material (2), the carrier material being provided with a donor material (3) that delivers ions to influence the patient's cellular metabolism in the implanted state, the carrier material (2) being interspersed with the donor material (3). The invention also relates to a method for producing an implant (1) of said type.

A prosthetic implant shaped as a portion of a human skeletal structure and including a contact and delivery portion shaped as a porous structure, in particular as a trabecular type structure, suitable for receiving a medical substance and configured to be arranged in contact with a bone of a patient during an operating configuration of the prosthetic implant and a support portion, coupled to the contact and delivery portion, including a plurality of ducts each having at least one inlet section, made at an operative part of the prosthetic implant that can be accessed from the outside by the surgeon in the operating configuration, and at least one outlet section which opens into the contact and delivery portion. The contact and delivery portion is configured to deliver the medical substance evenly onto the bone when the medical substance is injected through at least one duct of said plurality of ducts during the operating configuration.

The present invention provides a method for stabilizing a fractured bone. The method includes positioning an elongate rod in the medullary canal of the fractured bone and forming a passageway through the cortex of the bone. The passageway extends from the exterior surface of the bone to the medullary canal of the bone. The method also includes creating a bonding region on the elongate rod. The bonding region is generally aligned with the passageway of the cortex. Furthermore, the method includes positioning a fastener in the passageway of the cortex and on the bonding region of the elongate rod and thermally bonding the fastener to the bonding region of the elongate rod while the fastener is positioned in the passageway of the cortex.

A method for treating a bone defect extending between a proximal bone structure and a distal bone structure of a patient may include resecting a region of bone between the proximal bone structure and the distal bone structure and encompassing the bone defect, positioning a biodegradable osteogenic scaffold within a biodegradable sleeve, coupling the biodegradable sleeve to a fixation member, positioning the biodegradable sleeve between the proximal bone structure and the distal bone structure, and attaching the fixation member to each of the proximal bone structure and the distal bone structure.

A femoral component kit includes a piston. The piston includes a notch formed in a bottom surface. The kit includes a femoral component mold having a mold body with a first sidewall, a second sidewall, and a bottom. The sidewalls and bottom define a recess for receiving an antibiotic-impregnated material. The recess includes depressed sections that are spaced apart by an inner section. The outer sections are transverse to a longitudinal axis of the mold. The inner section includes a keel that extends upward and has a height that sets a size of a femoral component produced using the mold. The keel is aligned with the notch when the piston is inserted within the mold. The notch and the keel may include one or more calibration markings that indicate increments of adjustments to the size of the femoral component and resulting flexion and extension gaps and joint space position.

Methods and devices for stabilizing spinal anatomical structures. Some example methods may include introducing a curved segment of an elongate fastener placement rod adjacent to a bone, providing a fastener at the leading end of the curved segment, and/or securing the fastener in place with respect to the bone.

A scaffold comprised of a plurality of PLLA layers, which may include stem cells, for regenerating bone or tissue. The PLLA layers are separated by a plurality of hydrogel layers. The PLLA layers comprise a nanofiber mesh having a piezoelectric constant to apply an electrical charge to the bone or tissue upon application of ultrasound energy.