This disclosure relates to orthopaedic implant systems and methods for repairing bone defects and restoring functionality to a joint. The implant systems and methods disclosed herein may include augments extending from respective baseplates. The augments may have an internal network for communicating material in the respective implant.

This application describes an implantable device for tissue repair comprising at least two fabrics with interconnecting spacer elements transversing, connecting, and separating the fabrics, forming the device. Some embodiments have fixation points which can be an extension of at least one of the fabrics. The implantable device allows modification of the two fabrics having varying constructions, chemistries, and physical properties. The spacer elements create a space between the two fabrics, which can be used for the loading of biological materials (peptides, proteins, cells, tissues), offer compression resistance (i.e. stiffness), and compression recovery (i.e., return to original dimensions) following deformation and removal of deforming load. The inclusive fixation points of the fabrics are designed to allow for fine adjustment of the sizing and tension of the device to promote integration with the surrounding tissues as well as maximize the compressive resistance. The fixation points can include either the first fabric, the second fabric, or the combination of both fabrics. This device is suitable for soft and hard tissue regeneration or replacement with a preference for musculoskeletal tissues including but not limited to cartilage (including hyaline (referred to as articular; e.g. cartilage on the ends of long bones), fibrous (e.g. meniscus or intervertebral discs), elastic (e.g. ear, epiglottis)), bone, muscle, tendon, ligament, and fat.

A system and method for sharing and absorbing energy between body parts. In one particular aspect, the system facilitates absorbing energy between members forming a joint such as between articulating bones. In one embodiment, there is provided a system for manipulating energy transferred by members defining a joint, the members collectively defining a path of motion and having a cartilage having an energy absorption component configured therebetween.

An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.

An implant for therapeutically separating bones of a joint has two endplates each having an opening through the endplate, and at least one ramped surface on a side opposite a bone engaging side. A frame is slideably connected to the endplates to enable the endplates to move relative to each other at an angle with respect to the longitudinal axis of the implant, in sliding connection with the frame. An actuator screw is rotatably connected to the frame. A carriage forms an open area aligned with the openings in the endplates. The openings in the endplates pass through the carriage to form an unimpeded passage from bone to bone of the joint. The carriage has ramps which mate with the ramped surfaces of the endplates, wherein when the carriage is moved by rotation of the actuator screw, the endplates move closer or farther apart.

A drug delivery system is provided in the form of a controlled release, bioerodible pellet for subdermal implantation. The pellet is bioerodible, and provides for the sustained release of a pharmacologically active agent over an extended time period. As such, the drug delivery system finds significant utility in chronic drug administration. Bioerosion products are water soluble, bioresorbed, or both, obviating the need for surgical removal of the implant. Methods for manufacturing and using the drug delivery system are also provided.

A surgical kit including a hydrogel implant suitable for use in a carpometacarpal joint includes an upper surface, a lower surface, and sidewalls extending between the upper surface and the lower surface, a plunger, and an introducer for depoloying the implant is provided.

The present invention provides a technological platform for bone regeneration. More specifically, the invention provides an implant comprising a plurality of polymeric casings at least one of which encases a bone void filler and at least one reinforcement component. Also provided is a method of regenerating bone by implanting one or more implants according to the present invention to a bone repair site.

A joint implant component (1, 1′; 101; 201) for administering a pharmaceutical product is disclosed, which comprises an implant shaft (10, 10′; 110; 210), a joint section (20, 20′; 120; 220) arranged at the proximal end of the implant shaft, a flush supply opening (3, 3′; 103; 203) and a backflush opening (4, 4′; 104; 204). At least one shaft flush channel (11, 11′; 111; 211) and one shaft backflush channel (12, 12′; 112; 212) extend along the implant shaft inside the implant shaft. The shaft flush channel is connected to the outside of the implant shaft via shaft flush holes (13, 13′; 112; 113) for discharging the pharmaceutical product, and the shaft backflush channel is connected to the outside of the implant shaft via at least one shaft backflush hole (14, 14′; 114; 214) for receiving the discharged pharmaceutical product. The flush supply opening is fluidically connected to the proximal end of the shaft flush channel and the backflush opening is fluidically connected to the proximal end of the shaft backflush channel. Also disclosed is a joint implant comprising two such joint implant components which are connected to one another by means of joint surface parts (30, 40; 230) and are pivotable relative to one another.

The invention provides a sleeve element (1) to be placed on a neck (53) of a prosthetic hip (51) or shoulder implant, wherein the sleeve element is made of a biodegradable elastically deformable material comprising a medical active agent to be released from the sleeve element. The sleeve element may comprise a longitudinal channel (2) and a longitudinal slit (3) extending over the length of the longitudinal channel and between the longitudinal channel and an outer surface of the sleeve element, wherein the sleeve element is elastically deformable between a closed state and an opened state, wherein a width of the longitudinal slit in the opened state is larger than the width of the longitudinal slit in the closed state. The invention also provides a prosthetic kit, comprising a prosthetic hip or shoulder implant having a neck, and the above sleeve element.