A medical implant for treating bone defects. The implant has at least one hollow body delimiting an inner chamber in the interior of the hollow body, a fluid feed line connected in a fluid-permeable manner with the inner chamber, and a fluid discharge line connected in a fluid-permeable manner with the inner chamber. The hollow body consists at least in places or wholly of at least one plastic material that is impermeable to liquids and permeable to oxygen and to carbon dioxide, such that oxygen is deliverable from a fluid passed through the hollow body to, and carbon dioxide is absorbable into the fluid from, the surroundings of the hollow body. Also disclosed is a bone defect treatment system having such a medical implant and the fluid, wherein the fluid contains oxygen and is suitable for absorbing oxygen, and to a method for gas-flushing a surface of a medical implant.

A system of prosthetic implants for a total knee replacement procedure is provided. The system includes a tibial component of a knee joint implant, a tibial insert configured to be positioned against the superior side of the platform of the tibial component, a first femoral component of a knee joint implant, and a second femoral component of a knee joint implant.

An orthopedic system for delivery of a therapeutic agent to a bone includes an elongate stem adapted to be inserted into an intramedullary canal, an inlet configured to receive the therapeutic agent, and one or more outlets configured to deliver the therapeutic agent to the bone. The elongate stem may comprise one or more protrusions to engage the bone, and one or more channels extending longitudinally therein, fluidly coupled to the inlet. The therapeutic agent flows from the inlet through the one or more channels and exits into the intramedullary canal through the one or more outlets. The system may be configured to allow one or more dimensions of the system to be adjusted to accommodate the anatomy of a patient.

The present disclosure describes an intervertebral disk replacement system. The system can include a tissue-engineered intervertebral disc that is combined with a bioresorbable stabilization system for structural guidance. The system can prevent or reduce intervertebral disk implant displacement and can increase the stiffness when compared to the implantation of the intervertebral disk implant without the stabilization system.

The present disclosure describes an intervertebral disk replacement system. The system can include a tissue-engineered intervertebral disc that is combined with a bioresorbable stabilization system for structural guidance. The system can prevent or reduce intervertebral disk implant displacement and can increase the stiffness when compared to the implantation of the intervertebral disk implant without the stabilization system.

An orthopedic system for delivery of a therapeutic agent to a bone includes an elongate stem adapted to be inserted into an intramedullary canal, an inlet configured to receive the therapeutic agent, and one or more outlets configured to deliver the therapeutic agent to the bone. The elongate stem may comprise one or more protrusions to engage the bone, and one or more channels extending longitudinally therein, fluidly coupled to the inlet. The therapeutic agent flows from the inlet through the one or more channels and exits into the intramedullary canal through the one or more outlets. The system may be configured to allow one or more dimensions of the system to be adjusted to accommodate the anatomy of a patient.

The invention is a modular interbody fusion device for fusing adjacent spinal vertebrae that is adapted to be implanted in a prepared interbody space including a first modular segment having a width including a first rail extending at least partially along one side of the width and beyond a periphery of a body portion of the first modular segment, a second modular segment having a width and slidably connected to the first rail on one side of the width and having a second rail extending at least partially along another side of the width and beyond a periphery of a body portion of the second modular segment, a third modular segment having a width and slidably connected to the second rail on one side of the width and wherein the device has an expanded position in which the second and third modular segments are extended along the first and second rails and positioned in a generally end to end configuration spaced apart by the rails prior to implantation and an implanted position in which the modular segments are positioned in a generally side by side configuration that defines a unitary body that mimics the planar shape of the vertebra such that the device contacts and supports the adjacent vertebra.

Described is a mould (1) for making a temporary prosthetic component for a knee in an operating room comprising: a first half-mould (10); a second half-mould (20) which can be coupled to the first half-mould (10) for forming a moulding chamber (C) for a temporary prosthetic component made of medical cement; and elements (30) for fixing the first half-mould (10) to the second half-mould (20). Each fixing element (30) has a rod (31) configured for connecting the first half-mould (10) to the second half-mould (20) and defining a weakness neck (32) configured to allow a facilitated breakage of the rod (31).

A vertebral body system and method having a polyaxial fastener receiving member, adjustable width plates and a pedicle screw having a pedicle threaded portion and a threaded portion for fastening to the vertebral body.

Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating.