A spacer device for the two-step treatment of prosthesis infections, made from biologically compatible and porous material designed to allow the possibility of adding pharmaceutical products, active and/or therapeutic ingredients, includes a first portion designed to be fixed to a corresponding bone bed remaining from a previous implant, and a second portion designed to be inserted in a corresponding articular area of the patient, the first portion and the second portion being attached by adjustable connecting means.

Provided is an implantable composite which includes a plurality of resorbable ceramic particles with or without a biodegradable polymer. The resorbable ceramic particles can be granules including carbonated hydroxyapatite and tricalcium phosphate in a ratio of 5:95 to 70:30. Some resorbable ceramic particles are granules, which include carbonated hydroxyapatite and β tricalcium phosphate in a ratio of 5:95 to 70:30. The resorbable ceramic particles have a particle size from about 0.4 to about 3.5 mm. The implantable composite is configured to tit at or near a bone defect as an autograft extender to promote bone growth. Methods of using the implantable composite are also provided.

Injectable bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities.

Spinal tissue distraction devices that include a member which has a pre-deployed configuration for insertion between tissue layers and a deployed configuration in which the member, by change of configuration, forms a support structure for separating and supporting layers of spinal tissue.

A method of pressure forming a brown part from metal and/or ceramic particle feedstocks includes: introducing into a mold cavity or extruder a first feedstock and one or more additional feedstocks or a green or brown state insert made from a feedstock, wherein the different feedstocks correspond to the different portions of the part; pressurizing the mold cavity or extruder to produce a preform having a plurality of portions corresponding to the first and one or more additional feedstocks, and debinding the preform. Micro voids and interstitial paths from the interior of the preform part to the exterior allow the escape of decomposing or subliming backbone component substantially without creating macro voids due to internal pressure. The large brown preform may then be sintered and subsequently thermomechanically processed to produce a net wrought microstructure and properties that are substantially free the interstitial spaces.

An adjustable spinal fusion intervertebral implant is provided that can comprise upper and lower body portions that can each have proximal and distal wedge surf aces disposed at proximal and distal ends thereof. An actuator shaft disposed intermediate the upper and lower body portions can be actuated to cause proximal and distal protrusions to converge towards each other and contact the respective ones of the proximal and distal wedge surfaces. Such contact can thereby transfer the longitudinal movement of the proximal and distal protrusions against the proximal and distal wedge surfaces to cause the separation of the upper and lower body portions, thereby expanding the intervertebral implant. The upper and lower body portions can have side portions that help facilitate linear translational movement of the upper body portion relative to the lower body portion.

An implant is provided that is operable to be disposed between and fuse two sections of a bone. The implant includes a material that is operable to abut against the two sections of the bone. The material is porous and/or fibrous and is operable to receive at least one cellular growth factor.

Vertebral body replacement apparatuses, systems, and methods are provided. In various examples, an implantable device is configured to be inserted between a first vertebral body and a second vertebral body. The implantable device includes a first endplate configured to contact a superior endplate of the first vertebral body. A central member is pivotably coupled to the first endplate. A second endplate is configured to contact an inferior endplate of the second vertebral body. The implantable device includes a first insertion configuration and a second load-bearing configuration. The first insertion configuration includes the central member at a first angular position with respect to the first endplate. The second load-bearing configuration includes the central member at a second angular position with respect to the first endplate and the second endplate in a load-bearing position.

The present invention provides a method for stabilizing a fractured bone. The method includes positioning an elongate rod in the medullary canal of the fractured bone and forming a passageway through the cortex of the bone. The passageway extends from the exterior surface of the bone to the medullary canal of the bone. The method also includes creating a bonding region on the elongate rod. The bonding region is generally aligned with the passageway of the cortex. Furthermore, the method includes positioning a fastener in the passageway of the cortex and on the bonding region of the elongate rod and thermally bonding the fastener to the bonding region of the elongate rod while the fastener is positioned in the passageway of the cortex.

The invention relates to a device for producing a spacer having a stem mold (1) which has an inner space (2), wherein the inner space (2) is accessible via a proximal opening (3) and wherein the stem mold (1) has a proximal wall (4) which peripherally delimits the proximal opening (3) of the stem mold (1), a head mold (5) which has in the interior thereof a hollow space (6), wherein the hollow space (6) has a spherical surface-shaped inner surface (7) and is accessible via a distal opening (8), wherein the head mold (5) has a distal wall (9) which peripherally delimits the distal opening (8) of the head mold (5), a metal core (10) which has a stem part (12), a head part (14) and a flange (16), wherein the flange (16) projects out from the metal core (10), is arranged between the stem part (12) and the head part (14) and has a proximal surface (18) and a distal surface (20), wherein the stem mold (1) and the stem part (12) are shaped such that the stem part (12) is arranged in the inner space (2), when the proximal wall (4) is resting against the distal surface (20), and wherein the head mold (5) and the head part (14) are shaped such that the head part (14) is arranged in the hollow space (6), when the distal wall (9) is resting against the proximal surface (18).

The invention also relates to a set with such a device and to a method for producing spacers with such a device.