In the present disclosure, an artificial joint stem includes a base extending in a vertical direction when a proximal side of a human body in use is defined as an upward direction, and a coating film containing a calcium phosphate-based material and an antimicrobial material disposed on a part of the base. The base includes one or more boundary lines on the base defined by a presence or absence of the coating film. The one or more boundary lines include a first boundary line located on a lower side of the base with respect to the coating film. The first boundary line is located so as to intersect the vertical direction. A component along the vertical direction of the first boundary line is smaller than a component along a width direction of the base.

Orthopedic implants produced by additive manufacture, followed by refinement of exterior and interior surfaces trough mechanical erosion, chemical erosion, or a combination of mechanical and chemical erosion. Surface refinement removes debris, and also produces bone-growth enhancing micro-scale and nano-scale structures.

Bone implants, including methods of use and assembly. The bone implants, which are optionally composite implants, generally include a distal anchoring region and a growth region that is proximal to the distal anchoring region. The distal anchoring region can have one or more distal surface features that adapt the distal anchoring region for anchoring into iliac bone. The growth region can have one or more growth features that adapt the growth region to facilitate at least one of bony on-growth, in-growth, or through-growth. The implants may be positioned along a posterior sacral alar-iliac (“SAI”) trajectory. The implants may be coupled to one or more bone stabilizing constructs, such as rod elements thereof.

Injectable bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities.

A method for structuring a surface of an implant (100) made from a plastic material by means of a counter-body (200) comprises the following steps: providing (S110) of a counter-body (200) including a surface (210); forming (S120) of a first surface structure (212) on the surface (210) of the counter-body, wherein a first surface structure (212) comprises a non-regular, randomly distributed pattern; and forming (S130) of a second surface structure (112) on the implant (100) by using the counter-body (200), wherein the second surface structure and the first surface structure (212) are complementary to each other.

For the purpose of firmly fusing a low-cost osteosynthetic implant having high osteoconductivity with a bone in a short period of time after implanting without having to perform treatment to restore surface hydrophilicity, a osteosynthetic implant is provided with a substrate that is formed of magnesium or a magnesium alloy and a porous anodic oxide coating that is formed on a surface of the substrate, wherein the anodic oxide coating has an outer surface that, due to the sizes and distribution of pores that are formed when generating the anodic oxide coating by means of anodic oxidation treatment, structurally prevents water from entering the pores while maintaining the hydrophilicity thereof.

The present invention implements a set of grooves/ridges created on Ti at the circumferential direction to increase surface area of implant in contact with bone. These grooves/ridges protect nanofiber matrix (NFM) made with Polycaprolactone (PCL) electrospun nanofiber (ENF) and collagen at the groove from physiological loading. Controlled fabrication of a ridge made with titanium nitride (TiN) around the circumference of Ti is provided using a plasma nitride deposition technique. PCL ENF may be deposited along the sub-micrometer grooves using the electrospin setup disclosed. The method provides for fabrication of microgroove on Ti using machining or TiN deposition and filling the microgrooves with the NFM. This method has proven through experimentation to be successful in increasing in vivo mechanical stability and promoting osseointegration on Ti implants. The immobilization of MgO NP and FN with the PCL-CG NFM on microgrooved Ti as provided in the invention optimizes biological performances of Ti.

The embodiments provide a spinal implant that is configured for midline insertion into a patient's intervertebral disc space. The spinal implant may have a body and the body comprises one or more apertures. The apertures receive fixation elements, such as a screw and the like. The fixation element may comprise one or more anti-backout features, such as a split ring. In addition, at least some of the apertures are designed to permit a predetermined amount of nutation by a fixation element. The apertures that allow nutation enable the fixation element to toggle from one position to another, for example, during subsidence of the implant in situ. Some of the apertures may be configured to rigidly lock with the fixation elements. Moreover, the spinal implant may include features, such as one or more bores, that can accommodate imaging marks to help guide a surgeon.

An implantable composition, method of making and using the implantable composition is provided. The implantable composition comprising a first set of fibers and a second set of fibers, the first set of fibers manufactured to have a first binding surface, the second set of fibers manufactured to have a second binding surface, the first binding surface of the first set of fibers configured to bind at least at or near the second binding surface of the second set of fibers and the second set of fibers configured to bind at least at or near the first binding surface of the first set of fibers.

An implant may include a body having a first portion and a second portion and a structural member having a central member curve. In addition, the structural member may be exposed on an outer surface of the implant. Further, the central member curve may include a winding segment, and the winding segment of the central member curve may wind around a fixed path extending from the first portion of the body to the second portion of the body. Also, the central member curve may make one or more full turns around the fixed path. And, the structural member may have a member diameter at the winding segment, wherein the winding segment has a winding diameter corresponding with the full turn around the fixed path and the member diameter is greater than the winding diameter.