Medical device implants disclosed herein may include an interior space and at least one bone on-growth structure disposed within the interior space. The bone on-growth structure may include a root coupled to an interior surface of the implant, or to a mesh insert disposed within the interior space of the implant. The root may extend into the interior space of the implant toward another opposing interior surface of the implant. The bone on-growth structure may also include a plurality of branches coupled to the root via a plurality of junctions. The plurality of branches may each project at a plurality of different angles with respect to the root. In some embodiments, the plurality of branches may each terminate within the interior space of the implant. In other embodiments, one or more branches may contact opposing interior surfaces of the implant. The medical device implants may also include one or more channels to enhance bone growth within the medical device implants.

Methods for treating an annulus fibrosis having a defect include inserting a flexible device into the defect. The flexible device is advanced distally beyond an outer layer of the annulus fibrosus. The flexible device is then expanded such that a width of the flexible device is larger than the defect, where the flexible device prevents escape of nucleus pulposus through the defect. The flexible device may have at least two appendages made from a shape-memory metal. Alternatively, the flexible device may have a U-shaped structure that includes a central portion and two legs. The flexible device may also be anchored to the annulus fibrosis and/or the vertebrae.

An acetabular cup for a hip prosthesis, which includes a cotyle body provided with a number of holes for the passage of fixing screws. T holes are connected to each other by a number of ribs which define a grid.

A device for containing bone graft material includes a mesh outer sleeve extending longitudinally from a proximal end to a distal end and sized and shaped to correspond to a profile of an outer surface of a target bone. The outer sleeve includes a longitudinal slot extending along a length thereof. The device also includes a mesh inner sleeve connected to an interior surface of the outer sleeve via at least one strut so that a bone graft collecting space is defined therebetween. The inner sleeve is sized and shaped to correspond to a profile of a medullary canal of the target bone. In addition, the device includes an interstitial mesh extending radially away from an exterior surface of the inner sleeve toward an interior surface of the outer sleeve to hold graft material in the bone graft collecting space.

The present invention provides a process to functionalize nanofiber membrane (NFM) on a total joint replacement (TJR) implant surface to support bone ingrowth and reduce macrophage-associated inflammation, the process comprising amending the implant surface by laser cutting microgrooves greater than 100 m in depth to protect functional PCL NFM from applied loading, induce a higher amount of osteoblast cell function, increase implant-bone contact area, and serve as a reservoir for the local delivery of biomolecules to increase osseointegration of the implant; depositing aligned fibers on the implant surface, the fibers aligned in the direction of the microgrooves and collected in layers until a thickness less than 30 m is reached and preferably in the range of 1 m to 10 m. Biofunctionalized NFM are used to indirectly attach biomolecules on said implant surface, or extracellular matrix proteins with biomolecules are immobilized and deposited on the PCL NFM coated implant.

This invention relates to and orthopedic implant having an expansion means adapted to increase the external surface area of the implant, the expansion means positioned to correspond to voids or depressions in the anatomy of a patient. Also described are method for the design and manufacture of such implants.

A prosthesis (1) for the trapeze-metacarpal joint of the thumb comprises a body (2) suitable for being arranged between the scaphoid (31) and the metacarpus (30) of the thumb, such body (2) has the shape of an Archimedean solid and operates as a spacer between the scaphoid (31) and the metacarpus (30).

An intervertebral implant for positioning within an intervertebral space between adjacent first and second vertebral bodies. The intervertebral implant includes an implant body extending along a longitudinal axis of the intervertebral implant that is adapted to align with a vertical axis of the spine. The implant body includes a top plate and a bottom plate disposed longitudinally opposite and spaced apart from the top plate along the longitudinal axis. Further, the implant body includes at least one cross-arm obliquely extending between the top plate and the bottom plate. Furthermore, the implant body includes a lattice structure disposed at least between the at least one cross-arm and the top plate and between the at least one cross-arm and the bottom plate.

An interbody cage, which has lattice-like or grid-like areas for better connection/fusion into the area of the vertebra. The cage has especially an outer frame, which includes massive support parts and, and an inner grid body. The frame determining the outer contour and the lattice or grid areas located within same are made in one piece. The cage is prepared by sintering, such as by electron beam melting or laser sintering.

Various embodiments of implant systems and related apparatus, and methods of operating the same are described herein. In various embodiments, an implant for interfacing with a bone structure includes a web structure, including a space truss, configured to interface with human bone tissue. The space truss includes two or more planar truss units having a plurality of struts joined at nodes. Implants are optimized for the expected stress applied at the bone structure site.