In one aspect, an implant for replacing subject tissue includes a nonbiologic portion and a biologic portion grown on the nonbiologic portion. The biologic portion may be grown on the nonbiologic portion before being implanted in the subject. The nonbiologic portion may comprise a porous metal substrate (e.g., scaffolding). The nonbiologic portion may be formed by 3D printing (i.e., additive manufacturing). The nonbiologic portion may be patient-specific. A robot may be used to shape the implant before implantation and/or to shape bone being replaced/resurfaced.

Embodiments of forming custom interbody implants that may be used to stabilize region(s) formed between mammalian bony segments, including systems and methods to produce a custom interbody element that may be used to stabilize or couple region(s) formed between two or more mammalian bony segments. Other embodiments may be described and claimed.

The present invention is for a systematic process of creating patient-specific implants by matching target mechanical properties (e.g., elastic modulus of bone) based on the bone density information from a patient's CT scan images. The present invention creates lattice scaffolds using conformal unit-cells while minimizing the deviations between as-fabricated scaffolds and as-designed scaffolds. The present invention also creates a metamodel that matches the elastic modulus values of lattice scaffolds to desired values by using a homogenization approach to determine the characteristics of the lattice structure at the unit-cell level. The utilization of the metamodel enables designing the scaffolds without requiring any optimization procedure.

Disclosed herein are systems and methods for manufacturing a prosthetic. The systems and methods can include receiving patient data and determining optimal design parameters for the prosthetic using the patient specific data and a machine learning model. The optimal design parameters can be exported so that the prosthetic can be manufactured.

Provided is a method of manufacturing a prosthesis for a fractured long bone of a patient, the method including the steps of: A) providing data representative of the fractured long bone in a patient; B) based on said data, designing the prosthesis specifically to the patient, the prosthesis including a stem part that is configured to secure fragment(s) of the fractured long bone at chosen securing position(s) that will apply chosen mechanical stress onto the bone fragments and reduce the risk of osteonecrosis of the bone fragments.

An orthopaedic prosthetic component includes a manufactured acetabular shell component having an outer wall and an additively manufactured augment coupled to the outer wall. The augment includes an outer surface that defines a customized patient-specific negative contour shaped to conform to a positive contour of a patient's bone. A method for manufacturing the prosthetic component is also disclosed.

A method of designing an orthopedic implant comprising: (a) iteratively evaluating possible shapes of a dynamic orthopedic implant using actual anatomical shape considerations and kinematic shape considerations; and, (b) selecting a dynamic orthopedic implant shape from one of the possible shapes, where the dynamic orthopedic implant shape selected satisfies predetermined kinematic and anatomical constraints.

A method for treating a bone includes cutting away a portion of the bone, including cutting non-planar features into the bone for engagement by implant components. The method further includes fitting the multiple implant components to the bone, with at least some of the multiple implant components engaging the non-planar features cut into the bone. The implant components interlock such that later added implant components secure earlier added implant components in place on the bone.

Devices, systems, techniques and methods for determining the fit of an implant and for determining one or more prognosticators, indicators or risk factors of postoperative performance are provided.

An artificial replacement disk configured to be positioned in between a superior vertebrae and an inferior vertebrae. The upper and lower surfaces match the surface morphologies of the corresponding vertebrae and may be textured to promote bone in-growth. The artificial replacement disk may comprise gripping structures to permit easy manipulation of the artificial replacement disk during surgical procedures.