A patient specific guide for hip replacement for patients undergoing hip replacement surgery. The guide works for correction of the acetabulum defects based on a finite element model, which detect the bone quality and guide the surgeons for the optimum screws trajectories. The guide surface reflects the acetabular morphology which provide a correct posting of the cup, especially for the complex case as bone loss, severe fractures and tumors. CT-scan images are used to construct the 3D model of the acetabulum bone, therefore a finite element and virtual surgery planning methods are applied to create the electronic file of the patient specific guide. In final step, the 3D printers are used to produce the patient specific guide.

A system and computer-implemented method for manufacturing an orthopedic implant involves segmenting features in an image of anatomy. Anatomic elements can be isolated. Spatial relationships between the isolated anatomic elements can be manipulated. Negative space between anatomic elements is mapped before and/or after manipulating the spatial relationships. At least a portion of the negative space can be filled with a virtual implant. The virtual implant can be used to design and manufacture a physical implant.

A method of repairing a fractured bone may include implanting a prosthetic stem into an intramedullary canal of the fractured bone. First and second bone segments of the fractured bone may be robotically machined to include first and second implant-facing surfaces that are substantially negatives of first and second surface portions of the first end of the prosthetic stem. The first and second tuberosities may be machined so that the first and second bone segments have first and second interlocking surfaces shaped to interlock with each other. During implantation, the first and second implant-facing surfaces are in contact with the first and second surface portions of the first end of the prosthetic stem, and the first interlocking surface interlocks with the second interlocking surface.

Glenoid components with asymmetric fixation points are provided. Also, methods and devices are provided for the optimization of shoulder arthroplasty component design through the use of medical imaging data, such as computed tomography scan data. The methodology may improve the understanding of glenoid anatomy through the use of medical imaging data and 3D modeling, and for glenoid components that exploit this methodology. The methodology provides for how anatomical features change based on the specific location in the glenoid. The methodology can optimize loading and fit at the bone-device interface. Asymmetrical glenoid components are provided with significantly improved initial fixation.

In one aspect of the invention a system and method is claimed for providing model parameters for three dimensional fabrication of anatomical structures by obtaining and reconstructing three dimensional image data with a medical imager wherein imaging acquisition parameters of the imaging system and/or reconstruction input parameters of the reconstructor are optimized for maximum geometry precision. Advantageously, the imaging system is further configured to obtain material and/or functional information of the anatomical structure model and that material information is used to incorporate the material information in the anatomical model.

An artificial replacement disk assembly comprised of a core in between two endplates. The endplates have outer surfaces that match the surface morphologies of the corresponding vertebral endplates. The endplates may have textured inner surface to form a strong fusion with the core during the fabrication process. The thick solid endplates strongly fused to the core create a very resilient implant. Gripping structures on the endplates may permit easy manipulation of the assembly during surgical procedures.

A customized resorbable three-dimensional scaffold for oral and maxillofacial bone grafting involves merging two sets of three-dimensional information obtained from a patient, the first set includes three-dimensional bone information and the second set includes three-dimensional teeth and tissue information. The merged information is used to generate a three-dimensional shape of the bone to be regenerated, a three-dimensional position of the missing tooth/teeth, and a three-dimensional model of the customized resorbable three-dimensional scaffold for oral and maxillofacial bone grafting. The three-dimensional model is used to generate the customized resorbable three-dimensional scaffold and resorbable connectors for the customized resorbable three-dimensional scaffold.

A computer-generated component file for fabricating an orthopedic implant is prepared. First and second select sections of an initial implant model of a computer-aided design model are set to first and second model porous sections. A remaining section of the initial implant model is left. All regions defining the first and the second select sections are spaced not more than a preset distance from a patient-specific bone model of the computer-aided design model as measured uniformly. The first and the second model porous sections are merged with a remaining section of the initial implant model to form at least a portion of a final implant model. The final implant model is stored in a component file configured to be accessed by a computer-aided manufacturing machine for use in fabricating the orthopedic implant. At least a portion of the orthopedic implant corresponds to the final implant model.

A personalized medical device intended for correction of defects, in particular in the orofacial area is multicomposite and comprises a hard tissue replacement and a soft tissue replacement. The hard tissue replacement is a hard core of biocompatible thermoplastic material and the soft tissue replacement is a biocompatible elastic substance. Preparation of personalized medical device even in the prenatal period using CT, MRI and 3D/4D electronic USG imaging and “additive manufacturing” technology.

A method for forming a prosthesis comprising a bone-like portion and a cartilage-like portion can comprise additively manufacturing a first positive mold in accordance with a portion of a first three-dimensional model of a portion of a bone. A first negative mold can be formed from the first positive mold. The bone-like portion can be created within the first negative mold. A second positive mold of the bone and a cartilage can be additively manufactured from a second three-dimensional model. A portion of the second three-dimensional model can correspond to a portion of the first three-dimensional model. A second negative mold can be formed from the second positive mold. The bone-like portion can be positioned in the second negative mold so that the second negative mold and the bone-like portion can define a cartilage space that can be filled with a material to form the cartilage-like portion of the prosthesis.