The invention relates to a device for producing a spacer having a casting mold lower part (1) with a cavity (2), a casting mold wall (3) which extends peripherally away from an edge of the cavity (2) and which is open on the opposite side, a casting mold upper part (5) with a shaping surface (6), wherein the casting mold upper part (5) can be inserted into an interior (4) of the casting mold lower part (1) and is displaceable in the direction of the cavity (2), such that a hollow space is formed which is delimited by the cavity (2), the shaping surface (6) and the casting mold wall (3) and in which the spacer is moldable, at least one container (7) for receiving excess bone cement paste, and at least one opening (8) in the shaping surface (6) and/or in the cavity (2), which opens into the at least one container (7) for receiving excess bone cement paste.

The invention also relates to a method for producing spacers using such a device.

Implantable devices for orthopedic, including spine and other uses are formed of porous reinforced polymer scaffolds. Scaffolds include a thermoplastic polymer forming a porous matrix that has continuously interconnected pores. The porosity and the size of the pores within the scaffold are selectively formed during synthesis of the composite material, and the composite material includes a plurality of reinforcement particles integrally formed within and embedded in the matrix and exposed on the pore surfaces. The reinforcement particles provide one or more of reinforcement, bioactivity, or bioresorption.

The invention relates to a method and a device for manufacturing an articular prosthesis implant using a mould comprising a ceramic imprint (1) moved by a piston (2), the ceramic imprint (1) pressing the thermoplastic material introduced into the mould.

A method for fabricating a resorbable scaffold for regeneration of meniscal tissue is disclosed. The method includes fabricating a polymer filament network using 3D printing in accordance with a digital model of the polymer filament network, such that the polymer filament network will include a first plurality of layers comprising the circumferentially-oriented filaments alternating with a second plurality of layers comprising the radially-oriented filaments, the polymer filament network having a three-dimensional shape and geometry between a first layer and a second layer which is substantially the same as a three-dimensional shape and geometry of the resorbable scaffold.

Embodiments herein are generally directed to spinal implants, systems, apparatuses, and components thereof that can be used in spinal fusion and/or stabilization procedures, as well as methods of installation. The spinal implants may include an intervertebral spacer and a plate member.

A mold for forming a joint spacer device or a part thereof includes a rigid container body having a first perimeter profile delimiting a first molding surface configured to shape a first portion of the joint spacer or part thereof; and a rigid cover provided with a second perimeter profile delimiting a second molding surface configured to shape a second portion of the joint spacer or part thereof. The rigid container body and the rigid cover are removably engageable to each other, at the first and the second perimeter profile, so as to delimit a cavity corresponding to the external configuration of the joint spacer or part thereof. The mold includes a weakening system on the rigid container body and on the rigid cover, making them separable into parts to enable the extraction of the spacer device or part thereof, molded therebetween.

The present invention relates to methods for bioresorbable and biodegradable casings having both micropores and macropores for providing shape, structure and containment to different bone grafting materials. Kits and methods of use are also described.

Embodiments herein are generally directed to spinal implants, systems, apparatuses, and components thereof that can be used in spinal fusion and/or stabilization procedures, as well as methods of installation. The spinal implants may include an intervertebral spacer and a plate member.

A glenoid implant system may include a main body formed of a polymer, a base, and an anchor formed of metal. The main body may define an articulating surface and an opposite bone-contacting surface. The base may be formed in the bone-contacting surface of the main body, the base including a hole formed therein. The anchor may have a main section and a threaded post extending from the main section. The anchor may include a plurality of ribs extending in a longitudinal direction of the main section, the plurality of ribs being spaced apart from one another in a circumferential direction of the main section. The anchor may further include a plurality of wedges disposed on a base of the anchor, the plurality of wedges adapted to contact the base formed in the bone-contacting surface of the main body when the threaded post is received within the threaded hole.

An anatomically-shaped, human bone graft may be cultivated ex vivo using a bioreactor capable of perfusing large complex porous scaffolds. Scaffolds derived from image-based modeling of a target are seeded with human mesenchymal stem cells and cultivated. A bioreactor configured to house complex three-dimensional scaffold geometries provides controlled flow for perfusion of the cells. Dense uniform cellular growth can be attained throughout the entire scaffold as a result of the medium perfusion. In an embodiment, the bioreactor has a mold into which perfusion medium is pumped under pressure and multiple ports through which the medium exits the mold.