A system for cleaning bone that includes a base unit with a motor, a cleaning head with a cleaning element and a mill head with a mill element. Both the cleaning head and the mill head are designed to be coupled to the base unit. Both the cleaning element and mill element have features that facilitate their coupling to the motor. When the cleaning head is attached to the base unit, a motor in the base unit rotates the cleaning element to remove soft tissue from the bone so as to clean the bone. The mill element is placed on the base unit and the cleaned bone placed in the mill head. The actuation of the base unit motor results in the actuations of the mill element. The actuation of the mill element converts the cleaned bone into bone chips.

The invention provides a plasticized tissue or organ that does not require special conditions of storage, for example refrigeration or freezing, exhibits materials properties that approximate those properties present in natural tissue, is not brittle, does not necessitate rehydration prior to clinical implantation and is not a potential source for disease transmission. Replacement of the chemical plasticizers by water prior to implantation is not required and thus, the plasticized bone or soft tissue product can be placed directly into an implant site without significant preparation in the operating room.

A method of denuding bone stock with a denuder, such as a bone stock denuder container, is disclosed. The bone stock is deposited into a wash chamber formed with a curved chamber wall. The bone stock is impacted with a stream of fluid under pressure to separate non-bone tissue from bone. Fluid and non-bone tissue are drained from the wash chamber.

A collector includes a container body defining an interior containment space and having an open end for access, and a cap in covering relation to the open end and having an opening for receiving therein a distal end of a kerrison-type rongeur. An improvement includes the cap including a first plurality of scrapers in the form of fingers for engaging and dislodging cut bone from the cutting area of the distal end of the rongeur and a second plurality of scrapers in the form of wipers for engaging and dislodging cut bone from the cutting area of the distal end of the rongeur when the distal end of the rongeur is withdrawn through the opening from the collector, the second plurality being arranged so as to permit insertion of the distal end of the rongeur through the opening into the collector without engaging the distal end of the rongeur.

Methods of forming a connective tissue-to-bone interface scaffolds (e.g., ligament-to-bone interface scaffolds, tendon-to-bone interface scaffolds, etc.). These scaffolds (grafts) may be formed from in such a way as to provide both a mineralized and demineralized layer in which the entire graft is flexible, compressible and compliant.

A system and method of processing bone is disclosed. A tissue separator is utilized to separate tissue comprising at least one of muscle, periosteum and connective tissue from bone in a safe, sterile and efficient manner. In one aspect, the particle reducer can include an impeller positioned with respect to a cutting surface on a drum. At least one of the impeller and the drum is rotated by a power source such that harvested tissue frictionally engages the cutting surface. In another aspect, a source of pressurized fluid can be directed at tissue to separate bone from non-bone tissue.

A system for cleaning bone that includes a base unit with a motor, a cleaning head with a cleaning element and a mill head with a mill element. Both the cleaning head and the mill head are designed to be coupled to the base unit. Both the cleaning element and mill element have features that facilitate their coupling to the motor. When the cleaning head is attached to the base unit, a motor in the base unit rotates the cleaning element to remove soft tissue from the bone so as to clean the bone. The mill element is placed on the base unit and the cleaned bone placed in the mill head. The actuation of the base unit motor results in the actuations of the mill element. The actuation of the mill element converts the cleaned bone into bone chips.

Methods of forming a connective tissue-to-bone interface scaffolds (e.g., ligament-to-bone interface scaffolds, tendon-to-bone interface scaffolds, etc.). These scaffolds (grafts) may be formed from in such a way as to provide both a mineralized and demineralized layer in which the entire graft is flexible, compressible and compliant.

A bone cleaning assembly (102, 602) with cleaning elements (690, 724, 1230, 1264) that remove soft tissue from bone stock. The module also includes a clearing element (778) that is periodically urged against the cleaning elements to remove bone stock trapped by the cleaning elements from the cleaning elements.

A denuder, such as a bone stock denuder container, is disclosed. The denuder includes a nozzle and a container body. The nozzle is configured to be fluidically coupled to a source of fluid and to direct a fluid stream. The container body includes curved chamber wall that forms a wash chamber. The wash chamber is configured to receive a bone stock. The nozzle is configured to direct the fluid stream to impact the curved chamber wall.