A filling device for dosed filling of a product from a product storage container into product dose receiving containers provided in a disposable isolator so to be protected against contamination. The device includes means for holding the product storage container together with the contents outside of the disposable isolator. The device includes a controllable product removal device for a dosed removal of the product from the product storage container. The device includes a product dispensing device for the dosed dispensing of the product to the product dose receiving containers. The device includes a line assembly interconnecting the product storage container and the product dispensing device to conduct the product to the product dispensing device. The device includes at least one ultrasonic flowmeter outside of the disposable isolator fixed to the outside of the line assembly to detect the flow rate. The device includes a controller for measuring the product dose.

A syringe assembly (2) that locks a syringe (10) to prevent backflow of medicament, the syringe assembly (2) comprising a syringe (10) including a barrel (12) configured to carry the medicament, a plunger (14) that communicates with the barrel (12), and a plunger head (16) disposed on a proximal end of the plunger (14), and a locking assembly (50) disposed around the barrel (12), wherein the locking assembly (50) prevents the plunger (14) from moving away from the barrel (12) to draw the medicament into the barrel (12).

Drug delivery system, injection device, transfer apparatus, vial holder and method of administering and transferring are disclosed which provide for passive warming of chilled injectable transferred through the transfer apparatus and into the injection device. The injection device may include a skin-facing surface including a skin boundary displacement extension or structure around a needle injection site to create a high pressure zone in the tissue. Radio frequency tracking and monitoring features for tracking patient compliance also may be provided.

An apparatus and method for aseptically filling a container utilizing an adaptor formed of severable and heat-sealable material connected to a tube and container. The adaptor includes a membrane which is unsealed to allow filling by a known filling machine. Once the adaptor tube and container is formed as a unit, it is sterilized. The adaptor is then severed and sealed, creating a usable aseptic liquid product.

A system is disclosed for producing a mixture to deliver to a treatment site. The system includes a mixing lumen attachable to a proximal end of a delivery system. A multi-lumen chamber can be removably connected to a proximal end of the mixing lumen and include a first lumen aligned with a second lumen. The first lumen can be configured to comprise a first constituent in a first state. The first lumen can include a first plunger to move the first constituent from the first lumen to the mixing lumen. The first lumen can terminate in a first port. The second lumen can be configured to include a second constituent. The second lumen can include a second plunger to distally move the second constituent and terminate in a second port. A vial adaptor can be included with a vial having a third constituent.

A system is disclosed for producing a mixture to deliver to a treatment site. The system can include a first chamber with an inner cavity including a first constituent and an outer cavity concentric with the first cavity and including a second constituent. A partition can be openable and separate the first and second cavities. A second chamber can include a third constituent and be concentric with the first chamber. Moving the first chamber and/or the second chamber relative to the other can cause the partition to open so that the first constituent and the second constituent mix with each other to form a first mixture. Applying a force to the system can cause the first mixture and the third constituent to egress through distal portions of the first and second chambers and mix together to form the mixture for delivery to the treatment site.

A system is disclosed for producing a mixture to deliver to a treatment site. The system can include a mixing lumen attachable to a proximal end of a delivery system. A multi-lumen chamber can be connected to a proximal end of the mixing lumen and include a first lumen aligned and adjacent a second lumen. The first lumen can receive a first constituent in a first state. The first lumen can include a first plunger to move the first constituent from the first lumen to the mixing lumen. The second lumen can include a second constituent and a second plunger to distally move the second constituent and the first constituent in a second state. Distally moving the second plunger causes the first constituent and the second constituent to be mixed together within the mixing lumen to form the mixture.

Devices, systems, and methods used to compound a first medicament and second medicament are disclosed. The devices include a single-use or single-dose vial containing a first medicament and configured to receive an ampule containing a second medicament. The vial includes a stopper and needle configured to inject the first medicament into the ampule to compound with the second medicament.

The present disclosure discloses a feeding system for treating liquid medical waste. The feeding system comprises a receiving container for storing liquid medical waste and a feeding container for accommodating a coagulant. The feeding container comprises an outlet and a seal for closing the outlet, and the receiving container comprises a feeding connector with a feeding channel. The feeding container and the receiving container are provided with a guide mechanism comprising guide lugs and guide slots, and the feeding connector is provided with a plurality of splitting portions arranged along the circumferential direction of the feeding channel and spaced apart from each other by a certain distance. The guide mechanism allows the operation of rotating the feeding container by a predetermined angle relative to the receiving container, and this operation causes the splitting portions to cut the seal along the circumference of the feeding channel to destruct the seal, thereby causing the coagulant accommodated in the feeding container flows into the receiving container through the outlet. The present disclosure provides a safe and convenient operation manner for adding a coagulant into a storage container of liquid medical waste.

Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes controllable fluid pathways. The cartridge may include a syringe pump for moving fluid and/or gas, and one or more syringe valves or rotary valves for controlling which of the controllable fluid pathways is open for flow of the fluid and/or gas.