A drug mixing container is provided. The drug mixing container includes a container with an opening facing upward and a cover body. An inner peripheral wall of the container includes at least one piercing structure protruding toward the opening of the container. The cover body accommodates a drug and includes a sealing film for sealing the drug in the cover body. In use, when an opening of the cover body is coupled downward to the opening of the container, the sealing film is pierced and torn by the piercing structure to make the drug in the cover body flow into the container, thereby preventing hands of an operator from being stained with the drug.

Disclosed is a transfer device for use in reconstituting dry drugs and for diluting liquid drugs in drug containers. The transfer device includes a multi-port manifold and a connector suitable to be attached to a drug container, a first conduit to transfer a liquid entering an inlet port of the manifold through the connector and into the drug container, and a second conduit to transfer a gaseous fluid through the connector to an outlet port of the manifold. Also disclosed is a closed liquid transfer system which includes the transfer device, a tube connectable to the inlet port for transporting a liquid to the transfer device, a tube connectable to the outlet port for transporting the gaseous fluid away from the transfer device, and a gas collection container to collect the gaseous fluid in the gas transporting tube.

Connection equipment includes an equipment connector comprising a first connecting section, a first liquid flow path that communicates with a equipment, and a first valve that is to open and close the first liquid flow path, a container connector comprising a second connecting section, a second liquid flow path that communicates with the container, and a second valve that is to open and close the second liquid flow path, and a lock mechanism that locks the equipment connector and the container connector in a state where the first liquid flow path is in communication with the second liquid flow path, and that unlocks the connectors in a state where the first valve and the second valve are closed.

In drug mixing devices of disclosed embodiments, a main flow path extending from one end configured to allow liquid inside the first container to enter the main flow path therethrough to another end configured to allow liquid inside the second container to enter the main flow path therethrough, and a branch flow path branching from the main flow path are formed. The drug mixing device includes a body including a first connection part configured to be coupled with the first container and a second connection part configured to be coupled with the second container, and a backflow prevention part disposed in a partial flow path of the main flow path extending to the one end with reference to the connection point of the main flow path and the branch flow path, the backflow prevention part being configured to prevent liquid from flowing from the connection point to the one end.

A drug mixing kit according to a disclosed embodiment for mixing a first content in a liquid form in a first container with a second content in a liquid or powder form in a second container includes: a syringe forming therein an accommodation space in which a liquid is accommodated; and a drug mixing device coupled with the syringe and forming therein a drug flow path extending from one end configured to allow the liquid in the accommodation space to flow into the drug flow path therethrough to other end configured to allow the liquid in the second container to flow into the drug flow path therethrough.

A drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form.

Compositions and methods for separating a sample of whole blood or bone marrow aspirate into a fraction rich in at least one of platelets and pluripotent cells are provided. A sample of whole blood can be centrifuged in a collection tube comprising a separator substance formulated to settle between the PRP fraction and the at least one other fraction. Preferably, centrifugation is completed without substantial activation of platelets. Optionally, the separator substance could be hardened to form a solid barrier that allows removal of all or substantially all of the platelets in the PRP fraction without remixing of the PRP fraction with the at least one other fraction. Transfer devices and methods are also provided in which a sterile sample can be transferred from a separation/preparation container (e.g., vacutainer) to a consumer or other container (e.g., dropper) while maintaining sterility of the sample.

The present invention relates to a drug preparation and drug delivery device comprising: a drug preparation unit comprising at least two receptacles capable of containing constituents to be mixed, at least one of the receptacles being movable inside the drug preparation unit, a drug administration means, such as an injection or spray means, a fluid circuit capable of fluidically connecting the at least two receptacles and the administration means, the connecting of the fluid circuit with the at least two receptacles being made using at least two piercing means when said at least two receptacles move from an initial position to a contact position with said at least two corresponding piercing means, an electromechanical assembly for fluidically driving the constituents within the fluid circuit, characterised in that said drug preparation unit comprises a release mechanism comprising a compressed drive spring which, when it is released, is capable of generating a movement along an axis A1 of at least one of the movable receptacles towards at least one of said piercing means in order to create the fluid connection with the fluid circuit.

A multi-vial connector includes a main body, the upper side of which is coupled to a liquid medication extraction device, a plurality of sub-bodies arranged around the main body, a spike formed at the sub-body and inserted into a vial, and a liquid medication flow channel extending from the spike to the main body through the sub-body. A liquid medication can be extracted from a plurality of vials at the same time in a safe and convenient manner. The safety, convenience, and rapidity for extracting a liquid medication may be improved.

A drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form.