Various embodiments of the present invention are directed to transferring fluidic media from a vial to a reservoir. In various embodiments, fluidic media may be transferred from the vial to the reservoir by moving a housing portion to move a plunger head located in the reservoir to draw fluidic media from the vial to the reservoir. In other embodiments, fluidic media may be transferred from the vial to the reservoir while the reservoir is held by a holding unit and vibrated by a vibrator to remove air from the fluidic media. In some embodiments, fluidic media may be transferred from the vial to the reservoir by moving a handle operatively connected to a bias member for assisting with the transfer of fluidic media. In other embodiments, the transfer of fluidic media may be assisted by a bias member and a needle connecting atmosphere and the vial.

Liquid drug transfer device for use in a Ready-To-Use liquid drug transfer assemblage for establishing flow communication between a liquid source and an injection vial. The liquid drug transfer device includes an injection vial adapter for mounting on an intact injection vial having an injection vial stopper without puncturing same, a liquid source adapter for attachment to a liquid source, a dual ended liquid transfer member for flow communication with the liquid source and puncturing an injection vial stopper, a safety catch mechanism requiring an initial manual linear sliding extension for priming the liquid drug transfer device, an extension limit arrangement for limiting the linear sliding extension, and a snap fit securing arrangement for securing the liquid source adapter on the injection vial adapter after actuation.

A package that is configured to store and dispense fluids. The package includes a container and a dosing dispenser for closing an opening to the container. The dosing dispenser includes a body portion having a syringe receiver that is configured to receive a syringe to remove fluid from the container.

A package for administration of fluid medicinal or nutritional substances features an outer bag with a sterile or sterilized inner chamber and inside chamber a bottle of medicinal or nutritional substance with a neck, a pierceable cap and a device for the withdrawal and/or reconstitution of the substance, placed below the cap of the bottle. The device comprises a perforation needle axially movable to the bottle and an outflow tube extending out of the bag equipped with an openable closure. The perforation needle is crossed longitudinally by a first channel connecting with the closure set open to the outflow tube, and a second channel with a side opening equipped with a hydrophobic filter configured to allow, after perforation of the cap, only air or other gaseous fluids to flow from inside the bottle into the inner chamber of the bag or vice versa.

A transfer member (128) comprising a housing (24) having a top, a side wall (26), an open bottom, the open bottom permitting insertion of a vial (12) within the housing, a piercing member (34) mounted within the housing (24), the piercing member (34) having a piercing tip (36) located at a bottom end thereof, the piercing member having an interior passageway formed therein, a connector (30) located on an exterior side of the top, a moveable member (40) mounted within the housing (24), the moveable member (40) being moveable from a first position wherein the moveable member (40) prevents access to the piercing tip (36) to a second position permitting access to the piercing tip when the vial is inserted in the housing, a transfer member (128), the transfer member (128) having first and second transfer member ends (131, 133) wherein the moveable member (40) and the housing (24) cause the moveable member (40) to rotate when the moveable member (40) moves upwardly upon insertion of the vial (12), the moveable member returning to a third locked position upon removal of the vial, the third locked position being such that a further vial cannot be inserted into the housing, the first transfer member end (131) being connectable to the second adaptor end (123), the second transfer member end (133) being arranged to receive a neck of a vial (130).

A transfer device (10) for removing or transferring a medium out of or into a bottle (20) having a bottle neck (34) that can be closed by means of a closure (42), including a first adapter part (12), which can be positioned on the bottle, and a second adapter part (14), which interacts with the first adapter part, which can be displaced in the longitudinal direction of the bottle, and has a conducting element (50) for piercing the closure. After the second adapter part (14) has been displaced along the first adapter part in the direction of the closure (42) and the second adapter part has been locked, the first adapter part (12) is non-releasably fastened to or around the bottle (20).

A method of transferring a mixed drug from a drug mixing device in which drug has been mixed to a drug administration device id disclosed. The method comprises the steps of establishing a fluid coupling in an initial configuration between the drug mixing device and the drug administration device to create an assembly comprising the drug mixing device and drug administration device, wherein the drug administration device is located above the drug mixing device. The method includes the step of inverting the assembly to position it in an inverted configuration such that the drug administration device is located below the drug mixing device. The method includes the step of causing a flow of the mixed drug from the drug mixing device to the drug administration device when the assembly is in the inverted configuration. Also described is a drug mixing device comprising a container for holding a mixed drug and an exit transfer member fluidly connected to the container, the exit transfer member for transferring at least some of the mixed drug to a drug administration device. The exit transfer member is arranged such that fluid flow of the mixed drug between the drug mixing device and the drug administration device can occur only when the fluid transfer assembly is placed substantially in a specified orientation.

A transfer system for containers comprises at least a first container (1) and at least a second container (5) that can be interconnected in a media-transferring way by a connection system (7). An encryption system (13, 21, 25, 31) is provided to allow or prevent a media-transferring connection between the respective assignable containers (1, 5).

A low-cost drug compounding system that can practically fit inside of a fume hood or the like is provided. The system can use a single pump operable in forward and reverse directions (or multiple pumps) to compound complex mixtures particularly including those requiring the creation of solutions from dry or powdered ingredients. A wireless link allows operation of the system remotely. In one embodiment, the system uses a disposable mixing tube set that can be discarded after mixing while still attached to the base ingredient containers used for the compounding thereby minimize the chance of personnel exposure.

The present invention provides devices and methods for establishing aseptic connections between two or more components or subassemblies. The devices may be used in medical devices such as drug delivery pumps (10). In some embodiments, a connection is made between a drug container (50, 1050, 2050) and a fluid pathway connection assembly (300, 1300, 2300). The fluid pathway connection assembly may include a connection hub (312, 1312, 2312), a piercing member (316, 1316, 2316), and a piercing member retainer (314, 1314, 2314). The assembly may further include a first film (318, 1318, 2318) covering a cavity (312A, 1312A, 2312A), thereby maintaining the aseptic condition of the cavity. The drug container may hold a fluid drug and include a pierceable seal (326, 1326, 2326). A second film (322, 1322, 2322) may cover a recess (328, 1328, 2328) formed by the seal and thereby maintain the aseptic condition of the interior of the chamber. The piercing member may be caused to pierce the first and second film and the pierceable seal to open a fluid pathway for delivery of the fluid drug through the fluid pathway connection assembly.