An assembly for mixing drug components includes a housing to at least partially hold a first drug component container and a second drug component container. The assembly also includes a transfer member having first and second ends to fluidly couple the respective first and second drug component containers. The assembly further includes a pressure member to fluidly couple the first drug component container to a pressure generation chamber. In addition, the assembly includes an energy storage member to generate pressure in the pressure generation chamber to transfer a fluid from the first drug component container into the second drug component container. Moreover, the assembly includes an exit member to fluidly couple the second drug component container to an exterior of the assembly.

There is featured a grasping facilitator that has one or more of a) to c) as set forth below: a) a combination having an annular core and a plurality of gripping ribs spaced about the annular core, with the core and gripping ribs being formed of an elastomeric material and the ribs extending about an upper part, outer part and bottom part of the core so as to leave an interior region of the core that is aligned radially with respective ribs exposed; b) a pliable collar having a main body with a plurality of ridges separated by concave recesses and a central aperture; c) a tray holder having an aperture or projection that has a configuration designed to conform with at least one of a) and b). There is further featured kit combinations of a) to c) above as well as methods of using and assembling one or all combinations of a) to c).

An attachment arrangement has a housing and a needle located within the housing. The arrangement allows administration ports of different sizes to be inserted into and secured within the housing. In certain embodiments, compliant retainers secure the administration port within the housing. In certain other embodiments, the administration port is secured within the housing when the housing is compressed against the administration port by a housing compression element. Once the administration port is secured within the housing, a fluid-tight seal is formed between the attachment device and the administration port.

The invention is a needle valve comprising at least one hollow needle and a seat. The hollow needle is comprised of a smooth surfaced hollow shaft and a port adapted to allow fluid communication between the interior and the exterior of said needle located in the side of the shaft at the distal end close to the tip of said needle. The seat comprises at least one bore adapted to accommodate one of the at least one needles through it. The needle and the bore can move one relatively to the other and the bore is provided in, or is fitted with, resilient material such that the outer diameter of the needle is greater than the inner diameter of at least part of the bore. As a result the passage of the shaft of the needle in the bore creates a closely-matched shaft and sheath, which blocks the passage of fluid through the port.

A liquid transfer device is provided having a trifurcated body that includes a vial adapter at a first end configured to telescopically mount on the crown of an IV bottle to puncture a stopper in the crown with a cannula, an IV port extending from an opposing second end of the trifurcated body, and a needleless self-sealing port extending from a third end of the trifurcated body and configured to couple with the male connector of an additive transfer device. Methods of using the liquid transfer device with an IV bottle, additive transfer device, and an infusion set to prepare an infusion liquid for administration to a patient are also provided.

A fluid transfer apparatus is illustrated and described. The fluid transfer apparatus includes a fluid inlet, a fluid outlet and a fluid transfer device. The fluid inlet is associated with a fluid receptacle receiving portion, and the fluid receptacle receiving portion is configured to receive and engage at least a portion of a fluid receptacle. The fluid transfer apparatus is configurable between a first isolation state, in which the fluid transfer device is isolated from the fluid receptacle, such that the fluid container is fluidically isolated from the fluid inlet, to a second coupled state, in which the fluid transfer device is engaged with the fluid receptacle, such that the fluid receptacle is in fluid communication with the fluid inlet.

A securing device for securing an infusion appliance to an infusion container includes a first fastening element, which is designed in such a way that it is connectable to a fastening region of the infusion container, and a second fastening element, which is arranged at a distance from the first fastening element and which is designed in such a way that it is connectable to a fastening region of the infusion appliance. At least one connection element connects the first fastening element and the second fastening element to each other. The securing device can be used for medical infusion and transfusion arrangements.

A vial adaptor comprises first and second housings coupled to each other, a sheath enclosing the first and second housings, and a spike disposed in the first and second housings. The first and second housings form a first chamber therein. The sheath and the first and second housings form therebetween a second chamber in air communication with the first chamber. The second housing is slidable relative to the first housing to cause the spike piercing through a front stopper to establish air and fluid communication with a vial attached to the vial adaptor, meanwhile to vary the volume of the first chamber and press the air into the second chamber. Upon a fluid being drawn from the vial, the air in the first and second chambers enters the vial to compensate the pressure reduction caused by the fluid drawn out to prevent fluid spillage or aerosolizing from the vial.

A pharmaceutical compounding system includes a plurality of vials and a receptacle. The system is arranged to remove substances stored within the vials and combine them within the receptacle to form a medication, and each vial is continuously maintained gripped within the system during preparation of the medication.

There is featured a grasping facilitator that has one or more of a) to c) as set forth below: a) a combination having an annular core and a plurality of gripping ribs spaced about the annular core, with the core and gripping ribs being formed of an elastomeric material and the ribs extending about an upper part, outer part and bottom part of the core so as to leave an interior region of the core that is aligned radially with respective ribs exposed; b) a pliable collar having a main body with a plurality of ridges separated by concave recesses and a central aperture; c) a tray holder having an aperture or projection that has a configuration designed to conform with at least one of a) and b). There is further featured kit combinations of a) to c) above as well as methods of using and assembling one or all combinations of a) to c).