Provided is a system and method for an anti-foaming needle assembly for avoiding foam generation when extracting a liquid from a vessel having a chamber with a bottom and opposite thereto an opening sealed with a penetrable and re-sealable stopper providing an inner surface above the chamber. More specifically, the anti-foaming needle assembly includes a needle base having: a first end and opposite thereto a second end and a sidewall there between, the second end structured and arranged for temporary connection to a syringe having a barrel and a plunger; a first needle having a hollow shaft and a first length extending from the first end to provide an open distal end above the first end, the first needle having a second end vented through the sidewall; and a second needle having a hollow shaft and a second length extending from the first end generally parallel to the first needle to provide, when inverted, a distal end above the first end and below the distal end of the first needle, the second needle having a second end in fluid communication with the second end of the needle base. An associated method of use is also provided.

A drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form.

Liquid drug transfer device for use in a Ready-To-Use liquid drug transfer assemblage for establishing flow communication between a liquid source and an injection vial. The liquid drug transfer device includes an injection vial adapter for mounting on an intact injection vial having an injection vial stopper without puncturing same, a liquid source adapter for attachment to a liquid source, a dual ended liquid transfer member for flow communication with the liquid source and puncturing an injection vial stopper, a safety catch mechanism requiring an initial manual linear sliding extension for priming the liquid drug transfer device, an extension limit arrangement for limiting the linear sliding extension, and a snap fit securing arrangement for securing the liquid source adapter on the injection vial adapter after actuation.

An apparatus includes a fluidic coupler including an opening. A first port is in fluid communication with the opening and is to interface with an inlet of a flow cell of a sensor device. A second port is to interface with an outlet of the flow cell of the sensor device. A third port is in fluidic communication with the second port. The apparatus further includes a mechanical assembly moveable between a first position and a second position. The fluidic coupler is secured to the flow cell of the sensor device in the first position. The fluidic coupler is disengaged from the flow cell of the sensor device in the second position.

A system for closed transfer of fluids includes a syringe adapter including a cannula having a first end and a second end with the second end positioned within the housing, and a seal arrangement positioned within the housing and movable within the housing with the seal arrangement including a membrane. The system including a second component including a membrane and a locking mechanism. The second component configured to be received by the syringe adapter such that the membrane of the seal arrangement engages the membrane of the second component. The locking mechanism including a biasing member and an engagement member positioned on the biasing member, with the engagement member configured to engage a portion of the housing of the syringe adapter to secure the second component to the syringe adapter when the second component is received by the syringe adapter.

A heat seal pouch includes a bag, a cylinder, a partition assembly, and an outer skeleton frame. The bag is configured to hold a provided liquid. The cylinder is configured to hold a provided powder. The partition assembly is between the bag and the cylinder. The partition assembly is operable to form an openable partition in a bottom of the cylinder for selectively separating the cylinder from the bag. The outer skeleton frame is configured to house and seal the bag, the cylinder and the partition assembly. Whereby the heat seal pouch is configured for storing, transporting and selectively mixing the provided powder with the provided liquid.

A device (1) and the use thereof for dispensing fluid under aseptic conditions. The device (1) comprises conveying device (2) and container (3) with a variable inner volume. The conveying device comprises cylinder (4) with at least three openings (5, 6, 7) which are arranged along longitudinal central axis (11). Displaceable first and second pistons (9, 10) are arranged in the cylinder. The end faces (11, 12) of the pistons and inner wall (13) of the cylinder, delimit a variable fluid volume (14). The first opening is brought into fluidic communication with dispensing opening (15) and the second opening is brought into fluidic communication with the container. Each of the pistons comprise three seals (16, 16, 16) which are offset and sealingly close off the cylinder. Adjacent piston seals have inner spacing (di) which is equal to a shortest spacing (aA1) between two adjacent openings (5, 6 or 6, 7).

A liquid transfer device is described. The liquid transfer device comprising a vial adapter comprising a puncturing cannula for puncturing an injection vial stopper, an IV spike and a substitute IV port holder for receiving a substitute IV port, and a flow control member port. The IV spike, the substitute IV port holder and the puncturing cannula are in flow communication with the flow control member port. The liquid transfer device comprising a flow control member sealingly inserted in the flow control member port. Rotation of the flow control member between a plurality of positions controls flow communication of the liquid transfer device, the positions comprising a mixing position for enabling flow communication between the IV spike and the puncturing cannula; and an administering position for enabling flow communication between the IV spike and the substitute IV port holder.

A system for purifying incoming fluid is modular and includes a heat exchanger module, an evaporator-condenser module and a compressor. The system components are arranged in a stacked configuration to facilitate gravitational flow of the purified fluid such that the purified fluid drains passively for collection. A system for preparation of ready-to-use treatment fluid includes the modular fluid purification system, a preparation station and a coupling device. The components are configured to be retained in a portable carrier that is manually operable for improved access to and mobility of the components. A coupling device can connect the flow channels of several components and can be used in preparing ready-to-use dialysate. A system prepares a receptacle and a ready-to-use treatment fluid in the receptacle.

Liquid transfer devices with an integral telescopic vial adapter for use with an infusion liquid container and an initially non-punctured intact discrete injection vial. The integral telescopic vial adapter is configured for initial telescopic snap mounting on a discrete injection vial leaving its injection vial stopper non-punctured until a subsequent compaction for puncturing the injection vial stopper. The integral telescopic vial adapter includes a safety catch mechanism for precluding advertent compaction from a pre-compacted state to a compacted state. The integral telescopic vial adapter includes a clamping arrangement for irreversibly clamping same in its final compacted state.