According to some embodiments of the present disclosure, an adaptor configured to couple with a sealed vial can include a connector interface. The adaptor can include one or more access channels (e.g., passages). In some cases the one or more access channels are in fluid communication with the connector interface. The adaptor can include a piercing member. The piercing member can include a regulator channel. The adaptor can include a regulator assembly. The regulator assembly can include a first regulator inlet. In some cases, the regulator includes a second regulator inlet. One or more of the first and second regulator inlets can include a filter configured to filter fluid passing into and/or out of the respective regulator inlets. One or more valves can be positioned between the first and/or second regulator inlets and the piercing member.

A method for obtaining a saliva sample from an animal, particularly a pig, by means of a receiving device and a collecting device with an integrated filter, and a method of using a collecting device with an integrated filter for obtaining a saliva sample from an animal, particularly a pig. In addition, a collecting device comprising a bag, a removable container and a filter, and a kit having such a collecting device, and a receiving device for taking saliva from an animal, particularly a pig.

A sealed sterile device for the aseptic separation and concentration of biological components, which includes: a tube sealed at first end and which has a mouth at second end; a plunger of flexible material, without an actuation rod, installed inside the tube with the possibility of longitudinal movement, and which has a hole for charging with a fluid to be separated and concentrated and discharging the separated fractions, the hole being provide with a valved female Luer lock connection, the plunger also having a purging duct provided with a self-sealing filter for the automatic purging of the air/gas contained in the tube during the filling of the tube with the fluid to be separated and concentrated; and a cap for protecting the connection-plunger assembly, couplable to the mouth of the tube.

A vial access device comprising an first housing comprising a vent body having a cover configured for reversibly hermetically sealing the vent body; a first spike having a proximal end and a distal end, the proximal end projecting from the first housing, the first spike having a fluid lumen and a vent lumen, each arranged parallel to the first longitudinal axis, the vent lumen in fluidic communication with the vent body; a shroud projecting the first housing and at least partially surrounding a portion of the first spike; the shroud configured to receive a vial or container; a connector member projecting from the first housing, the connector in fluid communication with the fluid lumen of the first spike. Methods of transferring solutions from medicament vials are also provided.

A vial access device includes an outer housing defining an annular space and an inner space, an inner housing, and a connector configured to engage a mating connector with the connector having a body defining a central passageway and a flange that extends radially outward from the body. The flange and the housing defining a filter space that is in fluid communication with the annular space. A pressure equalization system is positioned within the annular space of the outer housing. The device also includes a vial connection element configured to be secured to a vial and having a body and a spike member extending from the body. The spike member defining a fluid passageway and a vent passageway with the fluid passageway in fluid communication with the central passageway of the connector and the vent passageway in fluid communication with the filter space and the annular space.

The present disclosure is directed to a vial adapter for interconnecting a vial and a fluid delivery device, and, more particularly, to a vial adapter having a modular design consisting of separately constructed components cooperatively arranged and coupled to one another. The modular construction allows for rapid manufacturing reconfigurations of one or more components with minimal costs to create new vial adapter configurations that meet specific needs.

A system is disclosed for recovering autologous thrombin from a blood product. The blood product is drawn into an injecting syringe and a clot is allowed to form. A discharge port of the injecting syringe is communicably connected to an intake port of an aspirating syringe through a hydrophilic filter assembly. The injecting and aspirating syringes are simultaneously operated to transmit blood product through the filter such that fibrous clotting material and red blood cells are removed by the filter and a concentrated, high-quality thrombin solution is recovered.

In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.

The invention relates to a dissolution chamber (10) for use with a catheter for dissolving and preparing an aqueous solution of a water-soluble photosensitizing agent for installation into the bladder, e.g. for use in photodynamic diagnosis (PDD) or photodynamic therapy (PDT) of bladder cancer and to a method for preparing a liquid pharmaceutical preparation for delivery into a patient's bladder which includes the use of said dissolution chamber (10).

A disposable transfer device has an injection device support surface for receiving an on-body injection device thereon and a flow path arrangement for transfer of fluid into the injection device, the transfer device being configured to define preferential gripping areas for user gripping of an injection device when such device is located on the support surface and interfering areas for interfering with user gripping of the injection device in the interfering areas.