A61K8/345

Peptides with cell damage protection activity and liposomial formulations

Selected peptides have been found to repair, by means of nucleotide excision repair (NER), cellular DNA damaged by the exposure to external agents, in particular UV rays and are useful for cosmetic or pharmaceutical use thereof in skin treatment. Compositions for topical application that contain such peptides, preferably carried in liposomes, prevent and treat skin damage caused by the exposure to UV rays, including in subjects affected by xeroderma pigmentosum.

GEL COMPOSITION WITH HIGH OIL CONTENT, THE PREPARATION METHOD AND THE USE OF THE SAME
20220395436 · 2022-12-15 ·

It relates to a cosmetic composition in the form of a transparent or semi-transparent gel, comprising (a) an oil phase; (b) a surfactant portion comprising a first non-ionic surfactant and a second non-ionic surfactant; (c) an aqueous phase; and (d) at least one C.sub.2-C.sub.6 polyol; wherein the first nonionic surfactant comprises at least one alkyl polyglucoside and the second nonionic surfactant comprises at least one having the following general formula (I) or (II): R(X).sub.nOR′ (I) wherein, R represents a linear or branched C.sub.8-C.sub.30 alkyl group or C.sub.8-C.sub.30 alkenyl group; X represents —OCH.sub.2CH.sub.2— or —OCH.sub.2—CHCH.sub.3—; n represents an integer from 2 to 100; and R′ represents H, or a linear or branched C.sub.8-C.sub.30 alkyl group or C.sub.8-C.sub.30 alkenyl group; (II) wherein, the sum of x+y+z represents an integer from 2 to 100; and R.sub.1, R.sub.2, and R.sub.3, are the same or different and are each independently represents OH, or a linear or branched C.sub.8-C.sub.30 fatty acid ester group, with the proviso that at least one of R.sub.1, R.sub.2 and R.sub.3 is not OH. It also relates to a method for preparing the cosmetic composition and the use thereof. The cosmetic composition has high oil content, superior stability and desirable cleansing efficacy.

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Method for producing coating film by electrostatic spraying
11523670 · 2022-12-13 · ·

The present invention relates to preventing color transfer and sticking of powder-containing cosmetics to clothes or the like. A coating formation method of the present invention includes an electrostatic spraying step of electrostatically spraying a composition directly onto a skin surface onto which powder-containing cosmetics have been applied, thereby forming a coating on the skin. The composition contains a component (a) and a component (b) below. It is preferable that the method further includes a liquid agent applying step of applying a liquid agent containing one or more selected from water and oils that are in liquid form at 20° C. on the skin onto which the powder-containing cosmetics have been applied, wherein the liquid agent applying step is performed subsequent to the electrostatic spraying step. (a) One or more volatile substances selected from water, alcohols, and ketones; and (b) a polymer having a coating formation ability.

Cleansing compositions

A cleansing composition and method of using a cleansing composition, the cleansing composition including a blend of three different emollients, the emollients including a first stearic ester, a second stearic ester, and a branched hydrocarbon, where the first stearic ester and second stearic ester are different from each other.

Cosmetic composition and its use, dermocosmetic formulation

The present invention refers to dermocosmetic formulations for use against skin blemishes, especially melasma. The present invention minimizes or avoids the formation of melasma by acting in several stages of melanogenesis. A preferred embodiment of the invention refers to dermocosmetic formulations that act in several stages of melanogenesis, preferably, in the gene expression of tyrosinase-related proteins (TYRP-1 and TYRP-2) and Endothelin-1 (ET-1). Another embodiment of the invention refers to the cosmetic composition containing a combination of active ingredients that act on the gene expression of tyrosinase-related proteins (TYRP-1 and TYRP-2) and Endothelin-1 (ET-1). In another preferred embodiment of the invention, the use of said cosmetic composition to combat melasma is described.

Compositions comprising naturally derived preservatives

The invention is directed to a composition suitable for topical application that comprises a naturally derived preservative having benzoic acid or a derivative thereof. The composition is stable when preserved with the naturally derived preservative and when at a pH that is above the natural pH of skin to as high as 7.25.

PESONAL DENTAL CARE PRODUCT FOR PREVENTING DEMINERALISATION
20220387269 · 2022-12-08 ·

The present invention provides new dental care products comprising self-assembling peptides that are capable of undergoing self-assembly at a certain pH that are useful in dental care, in particular, useful for reducing or preventing demineralisation of teeth of a subject, in particular, for reducing or preventing further demineralisation of teeth of a subject. The dental care products comprises self-assembling peptides, in particular, comprise self-assembling peptides comprising the sequence of SEQ ID NO: 21, that are capable of undergoing self-assembly at a pH below 7.5, wherein the self-assembling peptides are essentially present in the dental care product in assembled form, and a pharmaceutically acceptable basis. The dental care product is an essentially solid product selected from the group consisting of chewing gum, soft chew, toffee, gelatin gum, chewy candy, chew toy, lozenge. Preferably, it is a chewy product. The dental care product is not abrasive. The dental care product is useful for reducing or preventing (further) demineralisation of a tooth surface of a subject with demineralised teeth, e.g., or a subject with xerostomia, hyopsalivation, bruxism, gastroesophageal reflux disease, dentine hypersensitivity and/or tooth erosion. Preferably, it is also useful for cleaning the tooth surface. Products of the invention are useful for animals and humans. The invention also provides a process for preparing the dental care products of the invention. The invention enables non-targeted treatment of a plurality of teeth, and it is independent of the diagnosis of caries.

WATER-DISPERSION EMULSION COMPOSITION, METHOD FOR MANUFACTURING THE SAME, EMULSION ADDITION-CURED COMPOSITION, AND COSMETIC
20220387265 · 2022-12-08 · ·

A water-dispersion emulsion composition containing: (A) an anionic surfactant; (B) an organopolysiloxane having at least two hydrosilyl groups in one molecule thereof shown in formula (I); (C) an organopolysiloxane having at least two olefinic unsaturated groups in one molecule thereof shown in formula (II); (D) a monohydric or polyhydric alcohol; and (E) water, where the water-dispersion emulsion composition has a milky-white appearance at 25° C. and has emulsion particles that are spherical particles having an average particle size of 2.0 μm or less. This provides: a water-dispersion emulsion composition that gives a cosmetic having reduced stickiness, excellent feeling on use, refreshing feeling, and temporal stability, and particularly excellent cosmetic sustainability, abrasion resistance, and soft focus effect; an emulsion addition-cured composition obtained by addition-curing the same; and a cosmetic formulated with the emulsion addition-cured composition.

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GLYCERIN DISPERSION AND COSMETIC
20220387270 · 2022-12-08 · ·

Provided are: a glycerin dispersion in which the dispersibility and storage stability of a hydrophobized inorganic powder are improved; and a cosmetic containing the glycerin dispersion. A glycerin dispersion containing a hydrophobized inorganic powder, in which an inorganic powder is used as a base and hydrophobicity is imparted by coating the inorganic powder with an organic surface treatment agent, a polyglycerin-based nonionic surfactant, and glycerin is provided.

SOLID SHAVING AID COMPOSITION

The present disclosure describes a razor cartridge including a housing having a front edge and a rear edge; shaving blades disposed between the front edge and the rear edge; and at least one shaving bar disposed in front of the blade(s) and/or rear of the blade(s) which includes a solid shaving aid composition that includes, relative to the total weight of the solid shaving aid composition: about 15 wt.-% to about 48 wt.-% of a soap base including of one or more fatty acid salts having from about 8 to about 24 carbon atoms and optionally one or more fatty acids having from about 8 to about 24 carbon atoms, at least about 35 wt.-% of one or more polyols including from ˜2 to ˜8 carbon atoms; the polyol selected from a group including glycerol, sorbitol, ethylene glycol, diethylene glycol, propylene glycol, dipropylene glycol, tripropylene glycol, methylpropane diol glycol.