Disclosed is a regenerating composition having skin lifting and anti-age effect based on chlorinated derivatives of acetic acid, propylene glycol and sodium hydroxide, for use in the treatment of skin blemishes caused by stretch marks, acne scars, sun damage, skin sagging, hyperpigmentation, scars in various parts of the body, such as face, neck, chest, breast, inner thighs, arms, mons pubis, labia majora, inguinal and perianal areas, which is capable of overcoming the problems which are still present in the products of the prior art, a process of preparing the composition, and a method of use.

A medicated cosmetic formulation is provided which comprises one or more vitamin A vitamers, one or more depigmentation agents, and a chemical exfoliant. More particularly, the formulation comprises one or more retinoids as vitamin A vitamers, hydroquinone and/or kojic acid as depigmentation agents, and salicylic acid as a chemical exfoliant. The formulation reduces wrinkles, the appearance of blemishes, and photoaging. In some embodiments, additional ingredients are included, such as skin-colored pigments and ultra violet protection agents. Each of the aforementioned ingredients are provided in ratios that are safe and effective to facilitate collagen production, cell turnover, and depigmentation, and to stimulate blood vessels in the skin.

The present disclosure provides compositions suitable for delivering lipophilic bioactive agents. The compositions may be utilized to treat numerous diseases and conditions that would benefit from the application of a lipophilic bioactive agent.

Described are compositions containing quinones that show activity in enhance DNA repair and/or prevent damage to DNA. The quinones are thymoquinone, lapachol, myrtucommulone C, or mixtures thereof, and can be formulated into cosmetic compositions for topical administration to a subject in need thereof. The cosmetic compositions can also include sunscreens, surfactants, sunless tanning agents, desquamation agents, antiperspirants, colorants, preservatives and mixtures; and a cosmetically acceptable carrier. The compositions should find use in methods for treating the signs of ageing in mammals via topical application to the skin or hair of the mammals.

The present invention relates to substituted stilbenes and dienones which exhibit unexpected dual activity, as inhibitors of NFB and as agonists (activators) of Nrf2. In particular, these compounds show dual activity and it has been discovered that these compounds are particularly useful in the treatment of certain cosmetic applications and in rejuvenating and beautifying skin and other keratinous tissue of a subject in need. Cosmetic compositions and methods of using said compositions in combination with other components are disclosed herein.

The present disclosure relates to methods for coloring hair. The methods include applying an aqueous coloring composition and heat to the hair. The coloring composition includes water and one or more colorants for coloring the hair. After application of the aqueous coloring composition to the hair, the hair having the coloring composition applied thereon is heated to a temperature of about 100 C. to about 200 C. for a period of time, for example, for about 5 seconds to about 5 minutes. The methods are quick, efficient, and effective.

The invention relates to an extract of the aerial parts of Lawsonia inermis, as well as its preparation method and the extract that can be obtained by said method. The invention also relates to a cosmetic dye composition comprising such an extract. The invention finally concerns a cosmetic method for dying keratin fibers comprising the application of such a composition.

A penis nourishing and invigorating cream that nourishes the dermis of a penis and promotes the widening of the arteries and blood vessels of the penis. The cream comprises of a distilled water, at least one antioxidant, at least on thickening agent, at least one preservative, at least one emulsifier, a skin penetrator, a mineral oil, and a nitric oxide generating natural supplement.

A topical composition for treating age spots and wrinkles includes at least one first skin-whitening agent, at least one wrinkle-reducing agent, and a pharmaceutically or cosmetically acceptable solvent. In a preferred embodiment, the composition includes two whitening agents and two wrinkle-reducing agents. The skin-whitening agents include a tyrosinase-inhibiting glycosylated hydroquinone and a blend of alpine plant-based extracts. The wrinkle-reducing agents include avian egg extract and stabilized vitamin C.

Compositions and methods are disclosed herein for inducing (up-regulating) the expression of sulfotransferases in the hair follicles, e.g., the scalp. Increasing sulfotransferase is beneficial for metabolizing pro-drugs that require sulfonation to be activated, e.g., minoxidil sulfate is the active metabolite of minoxidil. A method for combining the compositions described herein with topical minoxidil to enhance minoxidil treatment for androgenetic alopecia is described. Additional methods and compositions include the use of retinoid X receptor agonists, retinoic acid receptor agonists, and nuclear receptor agonists in an RXR-NR heterodimer. Additional methods and compositions include the use of a topical solution containing an alkalinizing agent or an alkalinizing agent used with a penetration enhancer for up-regulating the sulfonating capacity of hair bearing skin, hair follicles, and/or keratinocyte cells. In addition, compositions and methods for increasing or decreasing the growth rate of hair follicles is disclosed by altering the intracellular pH.