The present invention relates to treatment of various disorders, diseases or conditions associated with or mediated by oxidative stress arising from an imbalance between the production of and the ability to neutralize reactive free radicals. The present invention is directed to methods and compositions capable of scavenging reactive free radicals for therapeutically or prophylactically treating disorders associated with free radical-induced damage, said compositions comprising an amount of 2-(3-chlorophenylamino) phenylacetic acid (23CPPA) or a pharmaceutically acceptable salt thereof that interacts with free radicals generated by cellular metabolism or ultraviolet radiation. In some embodiments, the composition comprises pharmaceutically or cosmetically acceptable adjuncts. The present invention further provides one or more kits that are useful for delaying, treating or preventing the consequences of aging and free radical damage on the condition or appearance of the skin.

The invention relates to a composition comprising at least one oxidation base chosen from 2-methoxymethyl-para-phenylenediamine of formula (I), one of its addition salts, its solvates and/or the solvates of its salts, at least one oxidation coupler, at least one compound chosen from etidronic acid, its salts and their mixtures and at least one compound chosen from 2,6-dipicolinic acid, its salts and their mixtures.

The invention also relates to a method for dyeing keratin fibers, preferably the hair, comprising the application, to said keratin fibers, of the composition.

The invention relates to a composition comprising at least one oxidation dyeing base chosen from 2-methoxymethyl-para-phenylenediamine of formula (I), 2--hydroxypropyl-para-phenylenediamine of formula (II), an addition salt thereof, solvates thereof and/or solvates of the salts thereof, and at least one (poly)oxyalkylenated amino silicone.

The invention also relates to a process for dyeing keratin fibers, preferably the hair, which comprises the application of the composition to said keratin fibers.

The invention relates to a composition comprising at least one oxidation base chosen from 2--hydroxyethyl-para-phenylenediamine of formula (I), an addition salt thereof, solvates thereof and/or solvates of the salts thereof, at least one (poly)oxyalkylenated amino silicone and at least one polyol.

The invention also relates to a process for dyeing keratin fibers, preferably the hair, which comprises the application of the composition to said keratin fibers.

Cosmetic or dermatological composition comprising at least a merocyanine and a hydrotrope The present invention relates to a cosmetic or dermatological composition comprising an aqueous phase, and a merocyanine of formula (I):

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and at least one hydrotrope chosen from nicotinamide, caffeine, salicylic acid salts, the sodium salt of pyroglutamic acid (sodium PCA), sodium 1,3-benzenedisulfonate, sodium benzoate, sodium 4-pyridinecarboxylate, sodium benzenesulfonate, sodium p-toluenesulfonate (NaPTS), sodium butyl monoglycol sulfate (NaBMGS), 4-aminobenzoic acid HCl, sodium cumene sulfonate, N,N-diethyl nicotinamide, N-picolyl nicotinamide, N-allyl nicotinamide, 2-methacryloyloxyethyl phosphorylcholine, resorcinol, pyrogallol, N-picolylacetamide, procaine HCl, proline HCl, pyridine, 3-picolylamine, sodium ibuprofen, sodium xylene sulfonate (SXS), ethyl carbamate, pyridoxal hydrochloride, sodium benzoate, N,N-dimethylacetamide, N-methylacetamide, isoniazid, and mixtures thereof.

The subject matter of the present invention relates to an agent for oxidatively dyeing keratinous fibers, including, in a cosmetic carrier, (A) 4,5-diamino-1-(2-hydroxyethyl)-1H-pyrazole and/or one of the physiologically acceptable salts thereof as developer, (B) at least one p-diaminobenzene derivative from the group comprising p-toluylenediamine, 2-(2,5-diaminophenyl)ethanol, and/or one of the physiologically acceptable salts thereof as developer; (C) at least one m-diaminobenzene derivative from the group comprising 2-(2,4-diamino-phenoxy)ethanol, 1-methoxy-2-amino-4-(2-hydroxyethylamino)benzene, and/or one of the physiologically acceptable salts thereof as coupler, and (D) at least one m-dihydroxybenzene derivative from the group comprising resorcinol, 2-methylresorcinol, and/or 4-chlororesorcinol as coupler, wherein the molar ratio of all the developers of group (A) included in the agent to all the developers of group (B) included in the agent, i.e., the molar ratio (A)/(B), has a value of at least 1.2.

The subject matter of the invention relates to agents for oxidatively dyeing keratinic fibers, comprising, in a cosmetic carrier, (A) 4,5-diamino-1-(2-hydroxyethyl)-1H-pyrazole and/or one of the physiologically acceptable salts thereof as developer, (B) 2-(2,5-diaminophenyl)ethanol and/or one of the physiologically acceptable salts thereof as developer, (C) 2,6-bis(2-hydroxyethylamino)-1-methylbenzene and/or one of the physiologically acceptable salts thereof as coupler, and (D) at least one m-dihydroxybenzene derivative from the group comprising resorcinol, 2-methylresorcinol, and/or 4-chlororesorcinol as coupler.

A hair dye composition is characterized by containing (A) HC BLUE No. 2, (B) DISPERSE VIOLET 1, and (C) at least one of HC YELLOW No. 2 and HC YELLOW No. 4 and has a pH of 7-11. The mass ratio of the content of (A) HC BLUE No. 2 to the content of (B) DISPERSE VIOLET 1 is preferably 1 to 30. The hair dye composition preferably further contains (D) DISPERSE BLACK 9.

The subject matter of the present invention provides a composition for oxidatively coloring keratinic fibers, comprising, in a cosmetic carrier (A) as developer, 4,5-diamino-1-(2-hydroxyethyl)-1H-pyrazole and/or a physiologically acceptable salt thereof, (B) as developer, at least one p-aminophenol derivative from the group of p-aminophenol, 4-amino-3-methylphenol and/or a physiologically acceptable salt thereof, (C) as coupler at least one m-diaminobenzene derivative from the group 2-(2,4-diaminophenoxy)ethanol, 1-methoxy-2-amino-4-(2-hydroxyethylamino)benzene and/or a physiologically acceptable salt thereof, (D) as coupler at least one m-dihydroxybenzene derivative from the group of resorcinol, 2-methylresorcinol and/or 4-chlororesorcinol, the molar ratio of all group (A) developers to all group (B) developers in the composition, i.e. the molar ratio (A)/(B), being at least 1.2.

A multi-component packaging unit (kit of parts) for reductively decoloring dyed keratin fibers, includes (I) a container (A) containing a cosmetic agent (a) and (II) a container (B) containing a cosmetic agent (b) and (III) a container (C) containing an aqueous, cosmetic agent (c) produced separately from each other, wherein agent (a) in container (A) includes a reductant (a1) as defined herein and agent (c) in container (C) includes (c1) one or more compounds of formula (I),

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A method for reductively decoloring dyed keratin fibers includes using the multi-component packaging unit.