Disclosed is a premix comprising piroctone olamine, a co-solvent selected from sodium salicylate, sodium benzoate, para aminsobenzoic, sodium xylene sulfonate, iso-octanol, hexanediol, phenoxyethanol, carbamide, acetamide, carbamate and mixtures thereof, and water, wherein the weight ratio of co-solvent to water ranges from 1:20 to 1:1. Hair care compositions comprising the premix and methods of preparing the premix and the hair care compositions.

Various embodiments provide an antimicrobial composition comprising: a safe and effective amount of benzoic acid analog or analogs; a safe and effective amount of a buffer system of weak organic acids buffer with the negative log of the acid dissociation constant, pKa, between about 3.2 and 4.9; and a dermatologically acceptable carrier for the benzoic acid analogs and weak organic acid buffers, wherein the antimicrobial composition has a pH from about 3.2 to 4.9. In some embodiments, the antimicrobial composition comprises a safe and effective amount of an antimicrobial metal ion salt, a preferred salt being copper gluconate, at a level and pH that does not precipitate with the weak acid buffers.

Topical personal care compositions containing amino acids and 4-substituted resorcinols for potentiating glutathione synthesis within skin cells. The compositions can be used to improve skin appearance of chronological aging or photoaging, resulting from exposure to UV light/sunlight, or environmental pollutants. The compositions are also useful for attaining even skin color and reducing pigmentation, age spots and discoloration.

The invention provides a composition for oral cavity that can prevent the formation and maturation of biofilms in the oral cavity, improve the taste and the remaining sensation after use in the oral cavity, and is superior in the sense of use. The composition for oral cavity contains 0.001% by mass to 10% by mass of proteoglycan, an algefacient, and one or more members selected from the group consisting of an antimicrobial agent, an anti-inflammatory agent, and a vitamin.

A core shell microcapsule having a liquid core and an outer shell, in which the liquid core comprises solvent and a piroctone compound and the shell comprises polyurea formed from monomeric units of aliphatic isocyanates and amines.

The present invention relates to the use of a combination of ciclopiroxolamine and piroctone olamine without zinc pyrithione or of a dermatological or cosmetic composition comprising such a combination for combating dandruff and/or preventing the formation thereof.

Disclosed herein are oral care compositions comprising at least one phosphate/acrylate copolymer, at least one cationic antibacterial agent, at least one synthetic anionic linear polycarboxylate polymer, at least one surfactant, and zinc lactate. Also disclosed herein are methods for the treatment and/or inhibition of gum disease or halitosis comprising contacting the oral cavity with the oral care compositions disclosed herein, as well as methods of making the oral care compositions disclose herein.

The present invention is a composition and method of treatment for fragile skin, skin disorders, and skin conditions in general through topical systematic and periodic application of a formulation that generally may include ingredients such as but not limited to barrier repair ingredients such as but not limited to Skinmimics®, Retinol®, and glycolic acid; humectants such as but not limited to glycerin, propanediol, low and high molecular weight hyaluronic acids; redensifying agents such as but not limited to Timecode®, a lipo amino acid (palmitoyl glycine); and anti-inflammatory/anti-itch ingredients such as but not limited to soybean sterols, Timecode®, SymCalmin®, menthyl lactate, and niacinamide.

The present disclosure generally provides taste-modifying compositions that reduce the off taste of alkali metal salts of peroxymonosulfate. In some aspects, the disclosure provides uses of such taste-modifying compositions to reduce the off taste of an alkali metal salt of peroxymonosulfate, such as potassium peroxymonosulfate. In some other aspects, the disclosure provides compositions (such as comestible compositions or oral care compositions), which comprise an alkali metal salt of peroxymonosulfate and a taste-modifying composition of the present disclosure. In some embodiments, such compositions are in the form of a food product, a beverage product, or an oral care product, such as a toothpaste, a mouthwash, and the like.

The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.