The disclosure relates to the establishment of a cell line having immune tolerance property using an optimal temperature profiling technique under a human body-like environment, and use thereof. The stem cell line exhibits immune tolerance property as they consecutively secret and express HLA-G proteins, and the culture medium of the stem cells contains a large amount of proteins capable of recovering various physiological functions and extracellular vesicles, and thus, the novel cell line or a culture medium thereof can be effectively used in various industries such as medicines and cosmetics.

A hand-held device with a paddle, an arm and a handle. Using the handle and arm, the paddle is slapped/tapped against the face to, in effect, provide a workout for an individual's facial skin and facial muscles. One purpose of a workout for the facial muscles is to tighten the facial muscles by inducing/stimulating the production of new and healthy collagen, improve skin firmness and texture, and blood circulation. The skin's cells need good circulation to heal and produce collagen. The slapping/tapping of the face creates a superficial trauma to the skin and muscles which tricks the body into producing high levels of collagen to assist in the healing process without causing any actual damage to the skin.

A hand-held device with a paddle, an arm and a handle. Using the handle and arm, the paddle is slapped/tapped against the face to, in effect, provide a workout for an individual's facial skin and facial muscles. One purpose of a workout for the facial muscles is to tighten the facial muscles by inducing/stimulating the production of new and healthy collagen, improve skin firmness and texture, and blood circulation. The skin's cells need good circulation to heal and produce collagen. The slapping/tapping of the face creates a superficial trauma to the skin and muscles which tricks the body into producing high levels of collagen to assist in the healing process without causing any actual damage to the skin.

A cosmetic composition for topical skin application and for use in reducing the appearance of scars comprising a combination of arginine and glutamine. The composition comprises L-Arginine in combination for L-Glutamine and further comprises bromelain, tetrahydrobisdemethoxydiferuloylmethane and tetrahydrocurcumin. Additional ingredients include various antioxidants, moisturizers, skin protectants, and vitamins together to promote the healing of affected skin while reducing visible scarring.

A cosmetic composition for topical skin application and for use in reducing the appearance of scars comprising a combination of arginine and glutamine. The composition comprises L-Arginine in combination for L-Glutamine and further comprises bromelain, tetrahydrobisdemethoxydiferuloylmethane and tetrahydrocurcumin. Additional ingredients include various antioxidants, moisturizers, skin protectants, and vitamins together to promote the healing of affected skin while reducing visible scarring.

Facial cosmetic compositions include a cannabinoid and a retinoid. The compositions can also comprise an aliphatic oligopeptide, an acetylated oligopeptide, and/or hyaluronic acid. Methods of administering facial cosmetic compositions include topically and/or subtopically administering to facial skin of a subject.

Facial cosmetic compositions include a cannabinoid and a retinoid. The compositions can also comprise an aliphatic oligopeptide, an acetylated oligopeptide, and/or hyaluronic acid. Methods of administering facial cosmetic compositions include topically and/or subtopically administering to facial skin of a subject.

A composition comprising at least three probiotic microorganisms, at least three prebiotic compounds, and polymnia sonchifolia root juice. The probiotic microorganisms are preferably derived from at least lactococcus lactis, lactobacillus acidophilus, and lactobacillus casei. The prebiotic compounds are preferably derived from at least curcuma longa (turmeric) root extract, beta vulgaris (beet) root extract, and chicory root extract. The composition may also include lactic acid as a byproduct of fermentation by lactococcus lactis. The composition may be encapsulated allowing it to adhere to and remain on the skin more effectively and longer than without encapsulation.

A composition comprising at least three probiotic microorganisms, at least three prebiotic compounds, and polymnia sonchifolia root juice. The probiotic microorganisms are preferably derived from at least lactococcus lactis, lactobacillus acidophilus, and lactobacillus casei. The prebiotic compounds are preferably derived from at least curcuma longa (turmeric) root extract, beta vulgaris (beet) root extract, and chicory root extract. The composition may also include lactic acid as a byproduct of fermentation by lactococcus lactis. The composition may be encapsulated allowing it to adhere to and remain on the skin more effectively and longer than without encapsulation.

The present technology includes a set of topical compositions used in treating wounds or scars in accordance with the methods and protocols described herein. The set of topical compositions can include (i) a cleansing composition comprising polydimethylsiloxane (silicone) and Rosmarinus officinalis (rosemary) flower extract; (ii) a first treatment composition comprising Aloe barbadensis (aloe) leaf juice, Macadamia temifolia (macadamia) seed oil, and panthenol (vitamin B5); (iii) a second treatment composition comprising Aloe barbadensis (aloe) leaf extract, sodium hyaluronate, and allantoin; (iv) a third treatment composition comprising snail mucin extract; (v) a fourth treatment composition comprising tocopherol; and (v) a fifth treatment composition comprising retinol.