Described herein are compositions and methods of treating gastrointestinal diseases and disorders such as irritable bowel syndrome and small intestinal bacterial overgrowth.

N-(furan-2-ylmethyl)-7H-purin-6-amine, or a pharmaceutically acceptable salt or solvate thereof, for prevention and/or treatment of circadian rhythm disorders, circadian rhythm diseases and/or circadian rhythm dysfunctions is disclosed. The disorders, diseases and dysfunctions include, inter alia, jet-lag, social jet-lag, shift-work disorder, and circadian rhythm disturbance induced by neurodegeneration is also disclosed.

N-(furan-2-ylmethyl)-7H-purin-6-amine, or a pharmaceutically acceptable salt or solvate thereof, for prevention and/or treatment of circadian rhythm disorders, circadian rhythm diseases and/or circadian rhythm dysfunctions is disclosed. The disorders, diseases and dysfunctions include, inter alia, jet-lag, social jet-lag, shift-work disorder, and circadian rhythm disturbance induced by neurodegeneration is also disclosed.

This disclosure provides methods of using compositions comprising amino acid entities to reduce fat infiltration in muscle, particularly under conditions of muscle dysfunction. The disclosure also provides methods for enhancing muscle function by reducing fat infiltration in the muscle comprising administering an effective amount of the compositions to a subject in need thereof.

This disclosure provides methods of using compositions comprising amino acid entities to reduce fat infiltration in muscle, particularly under conditions of muscle dysfunction. The disclosure also provides methods for enhancing muscle function by reducing fat infiltration in the muscle comprising administering an effective amount of the compositions to a subject in need thereof.

This disclosure provides methods of using compositions comprising amino acid entities to reduce fat infiltration in muscle, particularly under conditions of muscle dysfunction. The disclosure also provides methods for enhancing muscle function by reducing fat infiltration in the muscle comprising administering an effective amount of the compositions to a subject in need thereof.

The present invention provides formulations comprising: L-threonine; Glycine; L-phenylalanine; DL-phenylalanine; Glutamine; NAD; and Magnesium, for use in the treatment of different types of addictions, such as: psychotropic medications, illicit drugs, tobacco and alcohol including, for example, but not limited to, narcotics, benzodiazepines, marijuana, cocaine, methamphetamines, antidepressants, and antipsychotics. The formulations of the present invention promote a detoxification process which facilitates that the brain repairs the damage caused by the abuse of addictive substances.

The present invention provides formulations comprising: L-threonine; Glycine; L-phenylalanine; DL-phenylalanine; Glutamine; NAD; and Magnesium, for use in the treatment of different types of addictions, such as: psychotropic medications, illicit drugs, tobacco and alcohol including, for example, but not limited to, narcotics, benzodiazepines, marijuana, cocaine, methamphetamines, antidepressants, and antipsychotics. The formulations of the present invention promote a detoxification process which facilitates that the brain repairs the damage caused by the abuse of addictive substances.

The field of the invention relates to compositions and methods for treating and/or preventing immune dysfunction.

The field of the invention relates to compositions and methods for treating and/or preventing immune dysfunction.